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Murcko scaffold

Ring system with 3 rings and 21 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
13
With full pages
4
Scaffold SMILES

C(=Cc1nnc(SCc2ccccc2)o1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1nnc(SCc2ccccc2)o1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-Benzylsulfanyl-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C17H14N2OS, CAS 672950-60-6
2-Benzylsulfanyl-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 672950-60-6C17H14N2OS
2-[(3,4-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C17H12Cl2N2OS, CAS 478047-56-2
2-[(3,4-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 478047-56-2C17H12Cl2N2OS
2-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide chemical structure, C17H13ClN2OS, CAS 1164453-19-3
2-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide
CAS 1164453-19-3C17H13ClN2OS
2-[(2,6-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C17H12Cl2N2OS, CAS 1164458-36-9
2-[(2,6-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 1164458-36-9C17H12Cl2N2OS
4-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide chemical structure, C17H13ClN2OS, CAS 1164556-35-7
4-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide
CAS 1164556-35-7C17H13ClN2OS
4-Fluorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide chemical structure, C17H13FN2OS, CAS 383148-19-4
4-Fluorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide
CAS 383148-19-4C17H13FN2OS
2-[(4-Methylphenyl)methylsulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C18H16N2OS, CAS 478047-50-6
2-[(4-Methylphenyl)methylsulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 478047-50-6C18H16N2OS
2-[(2,4-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C17H12Cl2N2OS, CAS 1164519-46-3
2-[(2,4-Dichlorobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 1164519-46-3C17H12Cl2N2OS
3-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide chemical structure, C17H13ClN2OS, CAS 478047-55-1
3-Chlorobenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide
CAS 478047-55-1C17H13ClN2OS
3-Methylbenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide chemical structure, C18H16N2OS, CAS 672950-61-7
3-Methylbenzyl 5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl sulfide
CAS 672950-61-7C18H16N2OS
Methyl 4-[({5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl}sulfanyl)methyl]benzenecarboxylate chemical structure, C19H16N2O3S, CAS 672950-62-8
Methyl 4-[({5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl}sulfanyl)methyl]benzenecarboxylate
CAS 672950-62-8C19H16N2O3S
2-[(3-Nitrobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole chemical structure, C17H13N3O3S, CAS 551920-95-7
2-[(3-Nitrobenzyl)sulfanyl]-5-[(E)-2-phenylethenyl]-1,3,4-oxadiazole
CAS 551920-95-7C17H13N3O3S
2-Benzylsulfanyl-5-[(E)-2-(2,4-dichlorophenyl)ethenyl]-1,3,4-oxadiazole chemical structure, C17H12Cl2N2OS, CAS 383148-18-3
2-Benzylsulfanyl-5-[(E)-2-(2,4-dichlorophenyl)ethenyl]-1,3,4-oxadiazole
CAS 383148-18-3C17H12Cl2N2OS