CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
9
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)C1CC(=O)N(CCc2ccccc2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1CC(=O)N(CCc2ccccc2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N-(2,4-Dimethylphenyl)-5-oxo-1-(2-phenylethyl)pyrrolidine-3-carboxamide chemical structure, C21H24N2O2, CAS 796115-80-5
N-(2,4-Dimethylphenyl)-5-oxo-1-(2-phenylethyl)pyrrolidine-3-carboxamide
CAS 796115-80-5C21H24N2O2
N-(3-Acetamidophenyl)-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide chemical structure, C21H22FN3O3, CAS 887678-38-8
N-(3-Acetamidophenyl)-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide
CAS 887678-38-8C21H22FN3O3
N-[4-(tert-Butylsulfamoyl)phenyl]-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide chemical structure, C23H28FN3O4S, CAS 887678-70-8
N-[4-(tert-Butylsulfamoyl)phenyl]-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide
CAS 887678-70-8C23H28FN3O4S
N-(2-Fluorophenyl)-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide chemical structure, C19H18F2N2O2, CAS 896925-01-2
N-(2-Fluorophenyl)-1-[2-(4-fluorophenyl)ethyl]-5-oxopyrrolidine-3-carboxamide
CAS 896925-01-2C19H18F2N2O2
1-[2-(4-Fluorophenyl)ethyl]-N-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C20H21FN2O2, CAS 897738-04-4
1-[2-(4-Fluorophenyl)ethyl]-N-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 897738-04-4C20H21FN2O2
N-(3,4-Dimethoxyphenyl)-1-[2-(3,4-dimethoxyphenyl)ethyl]-5-oxopyrrolidine-3-carboxamide chemical structure, C23H28N2O6, CAS 1081141-49-2
N-(3,4-Dimethoxyphenyl)-1-[2-(3,4-dimethoxyphenyl)ethyl]-5-oxopyrrolidine-3-carboxamide
CAS 1081141-49-2C23H28N2O6
Methyl 4-[({1-[2-(3,4-dimethoxyphenyl)ethyl]-5-oxopyrrolidin-3-yl}carbonyl)amino]benzoate chemical structure, C23H26N2O6, CAS 1081120-74-2
Methyl 4-[({1-[2-(3,4-dimethoxyphenyl)ethyl]-5-oxopyrrolidin-3-yl}carbonyl)amino]benzoate
CAS 1081120-74-2C23H26N2O6
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-hydroxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C21H24N2O5, CAS 1081145-41-6
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(4-hydroxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 1081145-41-6C21H24N2O5
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(3-hydroxyphenyl)-5-oxopyrrolidine-3-carboxamide chemical structure, C21H24N2O5, CAS 1144489-96-2
1-[2-(3,4-Dimethoxyphenyl)ethyl]-N-(3-hydroxyphenyl)-5-oxopyrrolidine-3-carboxamide
CAS 1144489-96-2C21H24N2O5