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Murcko scaffold

2,5-Bis(benzylsulfanyl)-1,3,4-thiadiazole scaffold

52 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
52
With full pages
22
Scaffold SMILES

c1ccc(CSc2nnc(SCc3ccccc3)s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Bis(benzylsulfanyl)-1,3,4-thiadiazole page
Murcko scaffold c1ccc(CSc2nnc(SCc3ccccc3)s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

2,5-Bis(benzylsulfanyl)-1,3,4-thiadiazole chemical structure, C16H14N2S3, CAS 10106-21-5
2,5-Bis(benzylsulfanyl)-1,3,4-thiadiazole
CAS 10106-21-5C16H14N2S3
5-[(4-Fluorophenyl)methylthio]-2-(phenylmethylthio)-1,3,4-thiadiazole chemical structure, C16H13FN2S3, CAS 499102-27-1
5-[(4-Fluorophenyl)methylthio]-2-(phenylmethylthio)-1,3,4-thiadiazole
CAS 499102-27-1C16H13FN2S3
2-(Benzylthio)-5-((4-nitrobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H13N3O2S3, CAS 477330-55-5
2-(Benzylthio)-5-((4-nitrobenzyl)thio)-1,3,4-thiadiazole
CAS 477330-55-5C16H13N3O2S3
2-[(4-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C17H15FN2OS3, CAS 499103-56-9
2-[(4-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-56-9C17H15FN2OS3
3-(((5-((4-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)ME)phenyl methyl ether chemical structure, C17H15FN2OS3, CAS 477329-13-8
3-(((5-((4-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)ME)phenyl methyl ether
CAS 477329-13-8C17H15FN2OS3
2-[(2-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C17H15FN2OS3, CAS 499103-55-8
2-[(2-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-55-8C17H15FN2OS3
2-[(4-Methoxybenzyl)sulfanyl]-5-[(4-methylbenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C18H18N2OS3, CAS 499103-78-5
2-[(4-Methoxybenzyl)sulfanyl]-5-[(4-methylbenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-78-5C18H18N2OS3
2-[(4-Methoxybenzyl)sulfanyl]-5-[(3-methylbenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C18H18N2OS3, CAS 499103-88-7
2-[(4-Methoxybenzyl)sulfanyl]-5-[(3-methylbenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-88-7C18H18N2OS3
2-[(3-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C17H15FN2OS3, CAS 499103-58-1
2-[(3-Fluorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-58-1C17H15FN2OS3
2-[(3-Methoxybenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C18H18N2O2S3, CAS 499103-61-6
2-[(3-Methoxybenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-61-6C18H18N2O2S3
2-(Benzylthio)-5-((4-methoxybenzyl)thio)-1,3,4-thiadiazole chemical structure, C17H16N2OS3, CAS 613226-41-8
2-(Benzylthio)-5-((4-methoxybenzyl)thio)-1,3,4-thiadiazole
CAS 613226-41-8C17H16N2OS3
4-[({5-[(4-Chlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)methyl]benzoic acid chemical structure, C17H13ClN2O2S3, CAS 499101-93-8
4-[({5-[(4-Chlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)methyl]benzoic acid
CAS 499101-93-8C17H13ClN2O2S3
2-((3-Fluorobenzyl)thio)-5-((4-fluorobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H12F2N2S3, CAS 477329-15-0
2-((3-Fluorobenzyl)thio)-5-((4-fluorobenzyl)thio)-1,3,4-thiadiazole
CAS 477329-15-0C16H12F2N2S3
2-[(3-Chlorobenzyl)sulfanyl]-5-[(4-chlorobenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C16H12Cl2N2S3, CAS 499101-92-7
2-[(3-Chlorobenzyl)sulfanyl]-5-[(4-chlorobenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499101-92-7C16H12Cl2N2S3
2-[(4-Methoxybenzyl)sulfanyl]-5-{[3-(trifluoromethyl)benzyl]sulfanyl}-1,3,4-thiadiazole chemical structure, C18H15F3N2OS3, CAS 499103-91-2
2-[(4-Methoxybenzyl)sulfanyl]-5-{[3-(trifluoromethyl)benzyl]sulfanyl}-1,3,4-thiadiazole
CAS 499103-91-2C18H15F3N2OS3
2-[(3,4-Dichlorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C17H14Cl2N2OS3, CAS 499103-77-4
2-[(3,4-Dichlorobenzyl)sulfanyl]-5-[(4-methoxybenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499103-77-4C17H14Cl2N2OS3
2-[(2,6-Dichlorophenyl)methylsulfanyl]-5-[(4-methoxyphenyl)methylsulfanyl]-1,3,4-thiadiazole chemical structure, C17H14Cl2N2OS3, CAS 499103-83-2
2-[(2,6-Dichlorophenyl)methylsulfanyl]-5-[(4-methoxyphenyl)methylsulfanyl]-1,3,4-thiadiazole
CAS 499103-83-2C17H14Cl2N2OS3
2-(Benzylthio)-5-((3,4-dichlorobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H12Cl2N2S3, CAS 477333-31-6
2-(Benzylthio)-5-((3,4-dichlorobenzyl)thio)-1,3,4-thiadiazole
CAS 477333-31-6C16H12Cl2N2S3
2,5-Bis((4-fluorobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H12F2N2S3, CAS 401641-24-5
2,5-Bis((4-fluorobenzyl)thio)-1,3,4-thiadiazole
CAS 401641-24-5C16H12F2N2S3
2-((2,5-Dimethylbenzyl)sulfanyl)-5-((4-methoxybenzyl)sulfanyl)-1,3,4-thiadiazole chemical structure, C19H20N2OS3, CAS 499103-92-3
2-((2,5-Dimethylbenzyl)sulfanyl)-5-((4-methoxybenzyl)sulfanyl)-1,3,4-thiadiazole
CAS 499103-92-3C19H20N2OS3
2-(Benzylthio)-5-((3-chlorobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H13ClN2S3, CAS 477332-71-1
2-(Benzylthio)-5-((3-chlorobenzyl)thio)-1,3,4-thiadiazole
CAS 477332-71-1C16H13ClN2S3
2-(Benzylthio)-5-((2,4-dichlorobenzyl)thio)-1,3,4-thiadiazole chemical structure, C16H12Cl2N2S3, CAS 477331-30-9
2-(Benzylthio)-5-((2,4-dichlorobenzyl)thio)-1,3,4-thiadiazole
CAS 477331-30-9C16H12Cl2N2S3
2-[(4-Chlorobenzyl)sulfanyl]-5-[(4-nitrobenzyl)sulfanyl]-1,3,4-thiadiazole chemical structure, C16H12ClN3O2S3, CAS 499101-84-7
2-[(4-Chlorobenzyl)sulfanyl]-5-[(4-nitrobenzyl)sulfanyl]-1,3,4-thiadiazole
CAS 499101-84-7C16H12ClN3O2S3
ME 4-(((5-((4-Nitrobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)methyl)phenyl ether chemical structure, C17H15N3O3S3, CAS 618432-18-1
ME 4-(((5-((4-Nitrobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)methyl)phenyl ether
CAS 618432-18-1C17H15N3O3S3