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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(CSc2cc(SCc3ccccc3)sn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2cc(SCc3ccccc3)sn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3,5-Bis((4-chlorobenzyl)thio)-4-isothiazolecarbonitrile chemical structure, C18H12Cl2N2S3, CAS 252725-31-8
3,5-Bis((4-chlorobenzyl)thio)-4-isothiazolecarbonitrile
CAS 252725-31-8C18H12Cl2N2S3
3,5-Bis((4-bromobenzyl)thio)-4-isothiazolecarbonitrile chemical structure, C18H12Br2N2S3, CAS 332110-08-4
3,5-Bis((4-bromobenzyl)thio)-4-isothiazolecarbonitrile
CAS 332110-08-4C18H12Br2N2S3
3,5-Bis[(2-chlorophenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile chemical structure, C18H12Cl2N2S3, CAS 24134-80-3
3,5-Bis[(2-chlorophenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile
CAS 24134-80-3C18H12Cl2N2S3
3,5-Bis[(4-tert-butylbenzyl)sulfanyl]-1,2-thiazole-4-carbonitrile chemical structure, C26H30N2S3, CAS 311333-71-8
3,5-Bis[(4-tert-butylbenzyl)sulfanyl]-1,2-thiazole-4-carbonitrile
CAS 311333-71-8C26H30N2S3
3,5-Bis[(3-methoxyphenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile chemical structure, C20H18N2O2S3, CAS 309278-29-3
3,5-Bis[(3-methoxyphenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile
CAS 309278-29-3C20H18N2O2S3
3,5-Bis[[(4-nitrophenyl)methyl]thio]-4-isothiazolecarbonitrile chemical structure, C18H12N4O4S3, CAS 332110-25-5
3,5-Bis[[(4-nitrophenyl)methyl]thio]-4-isothiazolecarbonitrile
CAS 332110-25-5C18H12N4O4S3
3,5-Bis[(2,6-dichlorophenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile chemical structure, C18H10Cl4N2S3, CAS 4744-56-3
3,5-Bis[(2,6-dichlorophenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile
CAS 4744-56-3C18H10Cl4N2S3
3,5-Bis[(4-methoxyphenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile chemical structure, C20H18N2O2S3, CAS 311333-57-0
3,5-Bis[(4-methoxyphenyl)methylsulfanyl]-1,2-thiazole-4-carbonitrile
CAS 311333-57-0C20H18N2O2S3