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Murcko scaffold

Ring system with 3 rings and 16 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
10
With full pages
6
Scaffold SMILES

O=c1[nH]c2ccc(N3CCNCC3)cc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccc(N3CCNCC3)cc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1,3-Dimethyl-5-nitro-6-piperazin-1-ylbenzimidazol-2-one chemical structure, C13H17N5O3, CAS 695204-45-6
1,3-Dimethyl-5-nitro-6-piperazin-1-ylbenzimidazol-2-one
CAS 695204-45-6C13H17N5O3
1,3-Diethyl-5-nitro-6-piperazin-1-ylbenzimidazol-2-one chemical structure, C15H21N5O3, CAS 696597-81-6
1,3-Diethyl-5-nitro-6-piperazin-1-ylbenzimidazol-2-one
CAS 696597-81-6C15H21N5O3
1,3-Dimethyl-5-(4-methylsulfonylpiperazin-1-yl)-6-nitrobenzimidazol-2-one chemical structure, C14H19N5O5S, CAS 695204-47-8
1,3-Dimethyl-5-(4-methylsulfonylpiperazin-1-yl)-6-nitrobenzimidazol-2-one
CAS 695204-47-8C14H19N5O5S
5-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]-1,3-dimethyl-6-nitrobenzimidazol-2-one chemical structure, C18H25N5O4, CAS 708243-65-6
5-[4-(2,2-Dimethylpropanoyl)piperazin-1-yl]-1,3-dimethyl-6-nitrobenzimidazol-2-one
CAS 708243-65-6C18H25N5O4
5-[4-(2-Hydroxyethyl)piperazin-1-yl]-1,3-dimethyl-6-nitrobenzimidazol-2-one chemical structure, C15H21N5O4, CAS 708251-41-6
5-[4-(2-Hydroxyethyl)piperazin-1-yl]-1,3-dimethyl-6-nitrobenzimidazol-2-one
CAS 708251-41-6C15H21N5O4
5-(4-Methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one chemical structure, C12H16N4O, CAS 1446786-35-1
5-(4-Methylpiperazin-1-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
CAS 1446786-35-1C12H16N4O
tert-Butyl 4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)piperazine-1-carboxylate chemical structure, C16H22N4O3, CAS 1581275-03-7
tert-Butyl 4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)piperazine-1-carboxylate
CAS 1581275-03-7C16H22N4O3
tert-Butyl 4-(3-methyl-2-oxo-1H-benzimidazol-5-yl)piperazine-1-carboxylate chemical structure, C17H24N4O3, CAS 2357114-47-5
tert-Butyl 4-(3-methyl-2-oxo-1H-benzimidazol-5-yl)piperazine-1-carboxylate
CAS 2357114-47-5C17H24N4O3
tert-Butyl (R)-3-methyl-4-(3-methyl-6-nitro-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-5-yl)piperazine-1-carboxylate chemical structure, C18H25N5O5, CAS 2135332-64-6
tert-Butyl (R)-3-methyl-4-(3-methyl-6-nitro-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-5-yl)piperazine-1-carboxylate
CAS 2135332-64-6C18H25N5O5
tert-Butyl (R)-4-(6-amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-5-yl)-3-methylpiperazine-1-carboxylate chemical structure, C18H27N5O3, CAS 2135331-57-4
tert-Butyl (R)-4-(6-amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-5-yl)-3-methylpiperazine-1-carboxylate
CAS 2135331-57-4C18H27N5O3