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Murcko scaffold

Ring system with 3 rings and 19 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
23
With full pages
18
Scaffold SMILES

S=c1[nH]nc(-c2ccccc2)n1N=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2ccccc2)n1N=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

4-((1Z)-2-(2-Furyl)-1-azavinyl)-5-(4-methylphenyl)-1,2,4-triazole-3-thiol chemical structure, C14H12N4OS
4-((1Z)-2-(2-Furyl)-1-azavinyl)-5-(4-methylphenyl)-1,2,4-triazole-3-thiol
C14H12N4OS
4-{[(E)-(5-Methylfuran-2-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4OS, CAS 418801-77-1
4-{[(E)-(5-Methylfuran-2-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol
CAS 418801-77-1C14H12N4OS
3-(4-Methoxyphenyl)-4-[(E)-(5-methylfuran-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4O2S, CAS 420104-09-2
3-(4-Methoxyphenyl)-4-[(E)-(5-methylfuran-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 420104-09-2C15H14N4O2S
5-(3-Chlorophenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4OS, CAS 478254-98-7
5-(3-Chlorophenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-98-7C14H11ClN4OS
5-(2-Chlorophenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4OS, CAS 478254-16-9
5-(2-Chlorophenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-16-9C14H11ClN4OS
5-(4-Fluorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9FN4OS, CAS 577699-37-7
5-(4-Fluorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 577699-37-7C13H9FN4OS
5-(2-F-PH)-4-(((5-Methyl-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11FN4OS, CAS 578734-03-9
5-(2-F-PH)-4-(((5-Methyl-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 578734-03-9C14H11FN4OS
3-(4-Chlorophenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C13H9ClN4OS, CAS 1286170-17-9
3-(4-Chlorophenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 1286170-17-9C13H9ClN4OS
5-(2-Methoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4O2S, CAS 478256-79-0
5-(2-Methoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478256-79-0C15H14N4O2S
5-(3-Methoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4O2S, CAS 613248-90-1
5-(3-Methoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 613248-90-1C15H14N4O2S
4-(2-Furanylmethylideneamino)-3-(4-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4OS, CAS 488826-98-8
4-(2-Furanylmethylideneamino)-3-(4-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 488826-98-8C14H12N4OS
3-(3,4-Dimethoxyphenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4O3S, CAS 487035-45-0
3-(3,4-Dimethoxyphenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 487035-45-0C15H14N4O3S
5-(2-Chlorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9ClN4OS, CAS 478254-24-9
5-(2-Chlorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-24-9C13H9ClN4OS
4-(((5-ME-2-Furyl)methylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4OS, CAS 478255-92-4
4-(((5-ME-2-Furyl)methylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478255-92-4C15H14N4OS
3-(3-Chlorophenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C13H9ClN4OS, CAS 478255-11-7
3-(3-Chlorophenyl)-4-[(E)-furan-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 478255-11-7C13H9ClN4OS
4-((2-Furylmethylene)amino)-5-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4O2S, CAS 478257-03-3
4-((2-Furylmethylene)amino)-5-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478257-03-3C14H12N4O2S
4-((2-Furylmethylene)amino)-5-(3-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4O2S, CAS 613249-03-9
4-((2-Furylmethylene)amino)-5-(3-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 613249-03-9C14H12N4O2S
4-((2-Furylmethylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4OS, CAS 478256-05-2
4-((2-Furylmethylene)amino)-5-(3-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 478256-05-2C14H12N4OS
4-((2-Furylmethylene)amino)-5-(3-isopropoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C16H16N4O2S, CAS 573944-76-0
4-((2-Furylmethylene)amino)-5-(3-isopropoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 573944-76-0C16H16N4O2S
5-(3-Ethoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C16H16N4O2S, CAS 497921-78-5
5-(3-Ethoxyphenyl)-4-(((5-ME-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 497921-78-5C16H16N4O2S
5-(2-Fluorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9FN4OS, CAS 587005-39-8
5-(2-Fluorophenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 587005-39-8C13H9FN4OS
5-(3-Ethoxyphenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4O2S, CAS 497921-90-1
5-(3-Ethoxyphenyl)-4-((2-furylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 497921-90-1C15H14N4O2S
5-(4-F-PH)-4-(((5-Methyl-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11FN4OS, CAS 587007-03-2
5-(4-F-PH)-4-(((5-Methyl-2-furyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 587007-03-2C14H11FN4OS