CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
11
With full pages
3
Scaffold SMILES

S=c1[nH]nc(CCn2cccn2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(CCn2cccn2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-[2-(3,5-Dimethyl-4-nitropyrazol-1-yl)ethyl]-4-(3-methoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H18N6O3S, CAS 958946-57-1
3-[2-(3,5-Dimethyl-4-nitropyrazol-1-yl)ethyl]-4-(3-methoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 958946-57-1C16H18N6O3S
4-(4-Chlorophenyl)-3-[2-(3,5-dimethyl-4-nitropyrazol-1-yl)ethyl]-1H-1,2,4-triazole-5-thione chemical structure, C15H15ClN6O2S, CAS 957510-69-9
4-(4-Chlorophenyl)-3-[2-(3,5-dimethyl-4-nitropyrazol-1-yl)ethyl]-1H-1,2,4-triazole-5-thione
CAS 957510-69-9C15H15ClN6O2S
4-(3-Chlorophenyl)-3-[2-(3,5-dimethyl-4-nitropyrazol-1-yl)ethyl]-1H-1,2,4-triazole-5-thione chemical structure, C15H15ClN6O2S, CAS 512825-82-0
4-(3-Chlorophenyl)-3-[2-(3,5-dimethyl-4-nitropyrazol-1-yl)ethyl]-1H-1,2,4-triazole-5-thione
CAS 512825-82-0C15H15ClN6O2S
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(3-chlorophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H15BrClN5S, CAS 512817-81-1
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(3-chlorophenyl)-1H-1,2,4-triazole-5-thione
CAS 512817-81-1C15H15BrClN5S
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-phenyl-1H-1,2,4-triazole-5-thione chemical structure, C15H16BrN5S, CAS 512817-08-2
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-phenyl-1H-1,2,4-triazole-5-thione
CAS 512817-08-2C15H16BrN5S
5-[2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)ethyl]-4-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C16H18BrN5OS, CAS 512816-75-0
5-[2-(4-Bromo-3,5-dimethyl-1H-pyrazol-1-yl)ethyl]-4-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512816-75-0C16H18BrN5OS
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H15BrFN5S, CAS 512816-66-9
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thione
CAS 512816-66-9C15H15BrFN5S
3-[2-(3,5-Dimethyl-4-nitropyrazol-1-yl)ethyl]-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H15FN6O2S, CAS 957511-09-0
3-[2-(3,5-Dimethyl-4-nitropyrazol-1-yl)ethyl]-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thione
CAS 957511-09-0C15H15FN6O2S
3-[1-(4-Bromopyrazol-1-yl)propan-2-yl]-4-(2,4-dimethylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H18BrN5S, CAS 1005703-04-7
3-[1-(4-Bromopyrazol-1-yl)propan-2-yl]-4-(2,4-dimethylphenyl)-1H-1,2,4-triazole-5-thione
CAS 1005703-04-7C16H18BrN5S
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H18BrN5S, CAS 512816-68-1
3-[2-(4-Bromo-3,5-dimethylpyrazol-1-yl)ethyl]-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 512816-68-1C16H18BrN5S
3-[1-(4-Bromo-3,5-dimethylpyrazol-1-yl)propan-2-yl]-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C17H20BrN5S, CAS 1005562-96-8
3-[1-(4-Bromo-3,5-dimethylpyrazol-1-yl)propan-2-yl]-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 1005562-96-8C17H20BrN5S