CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

38 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
38
With full pages
27
Scaffold SMILES

S=c1[nH]nc(-c2ccccc2)n1N=Cc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2ccccc2)n1N=Cc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

3-(4-Methoxyphenyl)-4-(thiophen-2-ylmethylideneamino)-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4OS2
3-(4-Methoxyphenyl)-4-(thiophen-2-ylmethylideneamino)-1H-1,2,4-triazole-5-thione
C14H12N4OS2
5-Phenyl-4-[(2-thienylmethylene)amino]-4H-1,2,4-triazole-3-thiol chemical structure, C13H10N4S2, CAS 418800-56-3
5-Phenyl-4-[(2-thienylmethylene)amino]-4H-1,2,4-triazole-3-thiol
CAS 418800-56-3C13H10N4S2
5-(4-Methoxyphenyl)-4-[(thiophen-2-ylmethylidene)amino]-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4OS2, CAS 420841-59-4
5-(4-Methoxyphenyl)-4-[(thiophen-2-ylmethylidene)amino]-4H-1,2,4-triazole-3-thiol
CAS 420841-59-4C14H12N4OS2
3-(4-Methoxyphenyl)-4-[(E)-(3-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4OS2, CAS 420842-41-7
3-(4-Methoxyphenyl)-4-[(E)-(3-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 420842-41-7C15H14N4OS2
5-(4-Chlorophenyl)-4-{[(E)-(5-methylthiophen-2-yl)methylidene]amino}-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S2, CAS 430455-40-6
5-(4-Chlorophenyl)-4-{[(E)-(5-methylthiophen-2-yl)methylidene]amino}-4H-1,2,4-triazole-3-thiol
CAS 430455-40-6C14H11ClN4S2
3-(4-tert-Butylphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C18H20N4S2, CAS 430447-97-5
3-(4-tert-Butylphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 430447-97-5C18H20N4S2
4-{[(E)-(5-Methylthiophen-2-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol chemical structure, C14H12N4S2, CAS 354785-25-4
4-{[(E)-(5-Methylthiophen-2-yl)methylidene]amino}-5-phenyl-4H-1,2,4-triazole-3-thiol
CAS 354785-25-4C14H12N4S2
5-(3-CL-PH)-4-(((3-ME-2-Thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S2, CAS 478254-67-0
5-(3-CL-PH)-4-(((3-ME-2-Thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-67-0C14H11ClN4S2
5-(2-F-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11FN4S2, CAS 573694-24-3
5-(2-F-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 573694-24-3C14H11FN4S2
5-(4-F-PH)-4-(((5-Methyl-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11FN4S2, CAS 573934-69-7
5-(4-F-PH)-4-(((5-Methyl-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 573934-69-7C14H11FN4S2
5-(4-Fluorophenyl)-4-((2-thienylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9FN4S2, CAS 586995-39-3
5-(4-Fluorophenyl)-4-((2-thienylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 586995-39-3C13H9FN4S2
3-(4-Chlorophenyl)-4-[(E)-thiophen-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C13H9ClN4S2, CAS 488858-04-4
3-(4-Chlorophenyl)-4-[(E)-thiophen-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488858-04-4C13H9ClN4S2
5-(2-Methoxy-PH)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4OS2, CAS 478257-28-2
5-(2-Methoxy-PH)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478257-28-2C15H14N4OS2
5-(2-Methoxy-PH)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4OS2, CAS 478256-52-9
5-(2-Methoxy-PH)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478256-52-9C15H14N4OS2
5-(3-Meo-phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4OS2, CAS 478257-79-3
5-(3-Meo-phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478257-79-3C15H14N4OS2
5-(2-CL-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S2, CAS 478254-39-6
5-(2-CL-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-39-6C14H11ClN4S2
5-(3-CL-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S2, CAS 478255-28-6
5-(3-CL-Phenyl)-4-(((5-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478255-28-6C14H11ClN4S2
3-(3,4-Dimethoxyphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H16N4O2S2, CAS 497241-95-9
3-(3,4-Dimethoxyphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 497241-95-9C16H16N4O2S2
5-(2-CL-Phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H11ClN4S2, CAS 478253-87-1
5-(2-CL-Phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478253-87-1C14H11ClN4S2
3-(4-Methylphenyl)-4-[(E)-(3-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4S2, CAS 489442-47-9
3-(4-Methylphenyl)-4-[(E)-(3-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489442-47-9C15H14N4S2
3-(2-Methylphenyl)-4-[(E)-thiophen-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4S2, CAS 489464-83-7
3-(2-Methylphenyl)-4-[(E)-thiophen-2-ylmethylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489464-83-7C14H12N4S2
3-(2-Methylphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4S2, CAS 489414-74-6
3-(2-Methylphenyl)-4-[(E)-(5-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489414-74-6C15H14N4S2
5-(2-Chlorophenyl)-4-((2-thienylmethylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C13H9ClN4S2, CAS 478254-26-1
5-(2-Chlorophenyl)-4-((2-thienylmethylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-26-1C13H9ClN4S2
5-(3-ME-Phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H14N4S2, CAS 478255-58-2
5-(3-ME-Phenyl)-4-(((3-ME-2-thienyl)methylene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478255-58-2C15H14N4S2