Murcko scaffold
2-Phenylthiopyridine scaffold
320 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 320
- With full pages
- 44
Scaffold SMILES
c1ccc(Sc2ccccn2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 320 chemicals
![2-[(5-Nitropyridin-2-yl)sulfanyl]benzoic acid chemical structure, C12H8N2O4S, CAS 6285-15-0](/s/SUSSSASTTWVZSC-UHFFFAOYSA-N.svg)
2-[(5-Nitropyridin-2-yl)sulfanyl]benzoic acid
CAS 6285-15-0C12H8N2O4S
![1-tert-Butyl-3-[2-(2-chlorophenyl)sulfanylpyridin-3-yl]sulfonylurea chemical structure, C16H18ClN3O3S2, CAS 84881-83-4](/s/FQJBSEFHFHGMKJ-UHFFFAOYSA-N.svg)
1-tert-Butyl-3-[2-(2-chlorophenyl)sulfanylpyridin-3-yl]sulfonylurea
CAS 84881-83-4C16H18ClN3O3S2
3-Nitro-5-(2-pyridinylthio)benzenamine
CAS 208038-99-7C11H9N3O2S
![1-[3-Nitro-4-(2-pyridylthio)phenyl]ethan-1-one chemical structure, C13H10N2O3S, CAS 175137-44-7](/s/FCOYEURPIOTRFX-UHFFFAOYSA-N.svg)
1-[3-Nitro-4-(2-pyridylthio)phenyl]ethan-1-one
CAS 175137-44-7C13H10N2O3S
2-Nitro-1-(2-pyridylthio)-4-(trifluoromethyl)benzene
CAS 389084-12-2C12H7F3N2O2S
5-Nitro-2-phenylsulfanylpyridine
CAS 4262-10-6C11H8N2O2S
6-(Phenylsulfanyl)-3-pyridinamine
CAS 103983-07-9C11H10N2S
3-Nitro-4-(2-pyridylthio)benzoic acid
CAS 219930-74-2C12H8N2O4S
2-(Phenylthio)-3-pyridinecarboxylic acid
CAS 35620-72-5C12H9NO2S
2-((4-Methylphenyl)thio)-3-pyridinecarboxylic acid
CAS 955-53-3C13H11NO2S
![2-[(4-Chlorophenyl)sulfanyl]pyridine-3-carboxylic acid chemical structure, C12H8ClNO2S, CAS 955-54-4](/s/FPKVNUOJWZFDNZ-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)sulfanyl]pyridine-3-carboxylic acid
CAS 955-54-4C12H8ClNO2S
![2-[(4-Chlorophenyl)thio]nicotinamide chemical structure, C12H9ClN2OS, CAS 175135-82-7](/s/QLLYWFCCGPTQGT-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)thio]nicotinamide
CAS 175135-82-7C12H9ClN2OS
Methyl 3-nitro-4-(pyridin-2-ylthio)benzoate
CAS 346598-59-2C13H10N2O4S
![3-Nitro-2-[(4-methylphenyl)sulfanyl]pyridine chemical structure, C12H10N2O2S, CAS 98841-60-2](/s/FNKORSCJIMKGHT-UHFFFAOYSA-N.svg)
3-Nitro-2-[(4-methylphenyl)sulfanyl]pyridine
CAS 98841-60-2C12H10N2O2S
4-(Dimethylamino)-2-phenylsulfanylpyridine-3-carbonitrile
CAS 369607-11-4C14H13N3S
3-Pyridinecarboxylic acid, 6-methyl-2-(phenylthio)-
CAS 91718-65-9C13H11NO2S
Ethyl 2-(phenylsulfanyl)pyridin-3-yl ether
CAS 57883-19-9C13H13NOS
2-Phenylthiopyridine
CAS 3111-54-4C11H9NS
![2-[(4-Fluorophenyl)sulfanyl]-5-nitropyridine chemical structure, C11H7FN2O2S, CAS 887577-20-0](/s/IUSQSKCUZCNQRM-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)sulfanyl]-5-nitropyridine
CAS 887577-20-0C11H7FN2O2S
![2-[(4-Fluorophenyl)sulfanyl]-3-nitropyridine chemical structure, C11H7FN2O2S, CAS 887577-27-7](/s/AWNKYOQHMZMLDY-UHFFFAOYSA-N.svg)
2-[(4-Fluorophenyl)sulfanyl]-3-nitropyridine
CAS 887577-27-7C11H7FN2O2S
2-(Phenylsulfanyl)pyridin-3-amine
CAS 94924-89-7C11H10N2S
2-Bromo-6-phenylsulfanylpyridine
CAS 76700-38-4C11H8BrNS
![2-[(2-Chloro-4-nitrophenyl)thio]pyridine chemical structure, C11H7ClN2O2S, CAS 524955-87-1](/s/XLOWLZLIGWLAPQ-UHFFFAOYSA-N.svg)
2-[(2-Chloro-4-nitrophenyl)thio]pyridine
CAS 524955-87-1C11H7ClN2O2S
![2-[(2-Chlorophenyl)sulfanyl]-5-nitropyridine chemical structure, C11H7ClN2O2S, CAS 353277-31-3](/s/MPSSZZXHIKTHQT-UHFFFAOYSA-N.svg)
2-[(2-Chlorophenyl)sulfanyl]-5-nitropyridine
CAS 353277-31-3C11H7ClN2O2S
- 2-((4-Bromophenyl)thio)-3-nitropyridine200930-64-9C11H7BrN2O2S
- 6-[(2,4,5-Trichlorophenyl)sulfanyl]-3-pyridinamine353277-49-3C11H7Cl3N2S
- 2-[(4-Bromo-3-methylphenyl)sulfanyl]-5-nitropyridine353277-53-9C12H9BrN2O2S
- 2-(4-Chlorophenyl)sulfanylpyridin-3-amine353277-58-4C11H9ClN2S
- 2-{[3-(Trifluoromethyl)phenyl]sulfanyl}-3-pyridinol263390-47-2C12H8F3NOS
- 5-Nitro-2-[(2-methylphenyl)sulfanyl]pyridine353279-35-3C12H10N2O2S
- 6-[(2-Chlorophenyl)sulfanyl]-3-pyridinylamine353281-10-4C11H9ClN2S
- 2-(5-Chloro-2-nitrophenyl)sulfanylpyridine433253-73-7C11H7ClN2O2S
- 2-[(4-Chlorophenyl)sulfanyl]-4-methoxynicotinonitrile338773-69-6C13H9ClN2OS
- Methyl 5-cyano-6-[(4-methoxyphenyl)sulfanyl]-2-methylnicotinate303146-32-9C16H14N2O3S
- Methyl 5-cyano-2-methyl-6-(phenylsulfanyl)nicotinate303146-42-1C15H12N2O2S
- Methyl 6-[(4-chlorophenyl)sulfanyl]-5-cyano-2-methylnicotinate303146-43-2C15H11ClN2O2S
- Methyl 6-[(2-chlorophenyl)sulfanyl]-5-cyano-2-methylnicotinate303146-44-3C15H11ClN2O2S
- 5-Acetyl-6-methyl-2-(phenylsulfanyl)nicotinonitrile303146-50-1C15H12N2OS
- 5-Acetyl-2-[(4-chlorophenyl)sulfanyl]-6-methylnicotinonitrile303146-64-7C15H11ClN2OS
- 5-Acetyl-2-[(2-chlorophenyl)sulfanyl]-6-methylnicotinonitrile303146-65-8C15H11ClN2OS
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)aniline338406-70-5C12H8ClF3N2S
- N-(2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}phenyl)propanamide338407-17-3C15H12ClF3N2OS
- N-(2-((3-Chloro-5-(trifluoromethyl)-2-pyridinyl)sulfanyl)phenyl)-N'-ethylurea338407-35-5C15H13ClF3N3OS
- 2-Chloro-N-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}phenyl)acetamide338407-58-2C14H9Cl2F3N2OS
- N-(2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}phenyl)methanesulfonamide338407-66-2C13H10ClF3N2O2S2
- 4-(Dimethylamino)-2-[(4-methoxyphenyl)sulfanyl]nicotinonitrile341967-18-8C15H15N3OS
- {2-[(4-Chlorophenyl)sulfanyl]-3-pyridinyl}methyl N-isopropylcarbamate339278-52-3C16H17ClN2O2S
- 3-Chloro-2-[(4-chlorophenyl)sulfanyl]-5-(trifluoromethyl)pyridine204641-70-3C12H6Cl2F3NS
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cc2ccccc2)cc1952 chemicals
c1ccc(Oc2ccccc2)cc1933 chemicals
O=C(c1ccccc1)c1ccccc1537 chemicals
c1ccc(Nc2ccccc2)cc1395 chemicals
c1ccc(CN2CCCCC2)cc1283 chemicals
c1ccc(CN2CCNCC2)cc1267 chemicals
O=S(=O)(c1ccccc1)N1CCCCC1266 chemicals
c1ccc(Oc2ccccn2)cc1238 chemicals
c1ccc(Sc2ccccc2)cc1195 chemicals
O=S(=O)(c1ccccc1)N1CCNCC1195 chemicals
c1ccc(OC2CCCCO2)cc1164 chemicals
O=C(c1ccccc1)N1CCCCC1164 chemicals