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Murcko scaffold

Ring system with 4 rings and 22 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
4
With full pages
1
Scaffold SMILES

c1ccc(N2CCN(c3ccc4ccccc4n3)CC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(N2CCN(c3ccc4ccccc4n3)CC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Methyl 6-[4-(4,8-dimethyl-2-quinolinyl)piperazino]nicotinate chemical structure, C22H24N4O2, CAS 866136-67-6
Methyl 6-[4-(4,8-dimethyl-2-quinolinyl)piperazino]nicotinate
CAS 866136-67-6C22H24N4O2
3,7-Dimethyl-2-[4-(2-pyridinyl)-1-piperazinyl]quinoline chemical structure, C20H22N4, CAS 353254-17-8
3,7-Dimethyl-2-[4-(2-pyridinyl)-1-piperazinyl]quinoline
CAS 353254-17-8C20H22N4
4-Methyl-2-(4-pyridin-2-ylpiperazin-1-yl)quinoline chemical structure, C19H20N4, CAS 5541-90-2
4-Methyl-2-(4-pyridin-2-ylpiperazin-1-yl)quinoline
CAS 5541-90-2C19H20N4
7-Chloro-4-methyl-2-(4-pyridin-2-ylpiperazin-1-yl)quinoline chemical structure, C19H19ClN4, CAS 864425-32-1
7-Chloro-4-methyl-2-(4-pyridin-2-ylpiperazin-1-yl)quinoline
CAS 864425-32-1C19H19ClN4