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Murcko scaffold

2-(4-Phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one scaffold

25 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 25
With full pages: 4

Scaffold SMILES

O=C1CCCc2nc(N3CCN(c4ccccc4)CC3)ncc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(4-Phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one page

Murcko scaffold O=C1CCCc2nc(N3CCN(c4ccccc4)CC3)ncc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

7,7-Dimethyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H24N4O, CAS 850745-37-8

7,7-Dimethyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one

CAS 850745-37-8C₂₀H₂₄N₄O

2-(4-Phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H20N4O, CAS 777866-67-8

2-(4-Phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one

CAS 777866-67-8C₁₈H₂₀N₄O

4,7-Dimethyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H24N4O, CAS 777866-76-9

4,7-Dimethyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one

CAS 777866-76-9C₂₀H₂₄N₄O

4-Methyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H22N4O, CAS 777866-75-8

4-Methyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one

CAS 777866-75-8C₁₉H₂₂N₄O

7-Methyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H22N4O, CAS 774563-54-1

7-Methyl-2-(4-phenylpiperazin-1-yl)-7,8-dihydroquinazolin-5(6H)-one

CAS 774563-54-1C₁₉H₂₂N₄O

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H22N4O2, CAS 879625-35-1

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one

CAS 879625-35-1C₁₉H₂₂N₄O₂

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H24N4O2, CAS 879625-37-3

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 879625-37-3C₂₀H₂₄N₄O₂

2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H22N4O2, CAS 878442-72-9

2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one

CAS 878442-72-9C₁₉H₂₂N₄O₂

2-[4-(4-Methoxyphenyl)-1-piperazinyl]-4-methyl-7,8-dihydro-5(6H)-quinazolinone chemical structure, C20H24N4O2, CAS 878993-32-9

2-[4-(4-Methoxyphenyl)-1-piperazinyl]-4-methyl-7,8-dihydro-5(6H)-quinazolinone

CAS 878993-32-9C₂₀H₂₄N₄O₂

2-[4-(4-Fluorophenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H19FN4O, CAS 878442-74-1

2-[4-(4-Fluorophenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one

CAS 878442-74-1C₁₈H₁₉FN₄O

2-[4-(4-Fluorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H21FN4O, CAS 879625-43-1

2-[4-(4-Fluorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 879625-43-1C₁₉H₂₁FN₄O

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H21FN4O, CAS 880075-17-2

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 880075-17-2C₁₉H₂₁FN₄O

2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H21ClN4O, CAS 879766-25-3

2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 879766-25-3C₁₉H₂₁ClN₄O

4-Methyl-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H21F3N4O, CAS 879625-51-1

4-Methyl-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one

CAS 879625-51-1C₂₀H₂₁F₃N₄O

4,7-Dimethyl-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H23F3N4O, CAS 880075-53-6

4,7-Dimethyl-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one

CAS 880075-53-6C₂₁H₂₃F₃N₄O

2-[4-(4-Fluorophenyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H25FN4O, CAS 924870-17-7

2-[4-(4-Fluorophenyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one

CAS 924870-17-7C₂₁H₂₅FN₄O

2-[4-(2-Fluorophenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one chemical structure, C18H19FN4O, CAS 924857-76-1

2-[4-(2-Fluorophenyl)piperazin-1-yl]-7,8-dihydroquinazolin-5(6H)-one

CAS 924857-76-1C₁₈H₁₉FN₄O

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H25FN4O, CAS 924866-44-4

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4,7,7-trimethyl-7,8-dihydroquinazolin-5(6H)-one

CAS 924866-44-4C₂₁H₂₅FN₄O

2-[4-(2-Fluorophenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H21FN4O, CAS 924866-46-6

2-[4-(2-Fluorophenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 924866-46-6C₁₉H₂₁FN₄O

2-[4-(4-Fluorophenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H21FN4O, CAS 919722-45-5

2-[4-(4-Fluorophenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 919722-45-5C₁₉H₂₁FN₄O

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C21H26N4O2, CAS 919745-60-1

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one

CAS 919745-60-1C₂₁H₂₆N₄O₂

2-{4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one chemical structure, C19H19F3N4O, CAS 925600-20-0

2-{4-[3-(Trifluoromethyl)phenyl]piperazin-1-yl}-7,8-dihydroquinazolin-5(6H)-one

CAS 925600-20-0C₁₉H₁₉F₃N₄O

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H23FN4O, CAS 945342-64-3

2-[4-(2-Fluorophenyl)piperazin-1-yl]-4,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one

CAS 945342-64-3C₂₀H₂₃FN₄O

2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one chemical structure, C20H24N4O2, CAS 1030541-70-8

2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one

CAS 1030541-70-8C₂₀H₂₄N₄O₂

2-[4-(2-Methoxyphenyl)piperazin-1-yl]-7-methyl-7,8-dihydroquinazolin-5(6H)-one
1030560-21-4C₂₀H₂₄N₄O₂