CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
13
With full pages
10
Scaffold SMILES

O=c1cc(N2CCN(c3ccccc3)CC2)nc2ccccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(N2CCN(c3ccccc3)CC2)nc2ccccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

7-Methyl-4-oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H20N4O2, CAS 839680-02-3
7-Methyl-4-oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 839680-02-3C20H20N4O2
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H20N4O3, CAS 433317-07-8
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 433317-07-8C20H20N4O3
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C21H22N4O3, CAS 496011-40-6
2-(4-(2-Methoxyphenyl)piperazin-1-yl)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 496011-40-6C21H22N4O3
2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C19H17ClN4O2, CAS 433327-33-4
2-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 433327-33-4C19H17ClN4O2
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H20N4O3, CAS 850751-72-3
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 850751-72-3C20H20N4O3
4-Oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C19H18N4O2, CAS 839685-49-3
4-Oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 839685-49-3C19H18N4O2
9-Methyl-4-oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H20N4O2, CAS 839686-42-9
9-Methyl-4-oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 839686-42-9C20H20N4O2
2-[4-(2-Fluorophenyl)piperazin-1-yl]-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H19FN4O2, CAS 850730-40-4
2-[4-(2-Fluorophenyl)piperazin-1-yl]-9-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 850730-40-4C20H19FN4O2
2-[4-(4-Fluorophenyl)piperazin-1-yl]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H19FN4O2, CAS 838905-56-9
2-[4-(4-Fluorophenyl)piperazin-1-yl]-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 838905-56-9C20H19FN4O2
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C21H22N4O3, CAS 838890-96-3
2-[4-(4-Methoxyphenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 838890-96-3C21H22N4O3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C20H19FN4O2, CAS 838894-62-5
2-[4-(2-Fluorophenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 838894-62-5C20H19FN4O2
2-[4-(2-Fluorophenyl)piperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C19H17FN4O2, CAS 838869-33-3
2-[4-(2-Fluorophenyl)piperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 838869-33-3C19H17FN4O2
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C21H22N4O3, CAS 838893-69-9
2-[4-(2-Methoxyphenyl)piperazin-1-yl]-7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 838893-69-9C21H22N4O3