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Murcko scaffold

5-Phenyl-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one scaffold

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
12
With full pages
1
Scaffold SMILES

O=c1[nH]c(-c2ccccc2)nc2n[nH]nc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyl-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one page
Murcko scaffold O=c1[nH]c(-c2ccccc2)nc2n[nH]nc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Zaprinast chemical structure, C13H13N5O2, CAS 37762-06-4
Zaprinast
CAS 37762-06-4C13H13N5O2
1-Methyl-5-phenyl-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one chemical structure, C11H9N5O, CAS 71492-02-9
1-Methyl-5-phenyl-1H-[1,2,3]triazolo[4,5-d]pyrimidin-7(4H)-one
CAS 71492-02-9C11H9N5O
Diethyl (((3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)amino)methylene)malonate chemical structure, C21H24N6O6, CAS 66975-54-0
Diethyl (((3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)amino)methylene)malonate
CAS 66975-54-0C21H24N6O6
3-[2-[3-(6,7-Dihydro-7-oxo-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl)-4-propoxyphenyl]diazenyl]-2,4-pentanedione chemical structure, C18H19N7O4, CAS 67012-85-5
3-[2-[3-(6,7-Dihydro-7-oxo-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl)-4-propoxyphenyl]diazenyl]-2,4-pentanedione
CAS 67012-85-5C18H19N7O4
Benzamide, 3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-N-(1,1-dimethylethyl)-4-propoxy- chemical structure, C18H22N6O3, CAS 66975-70-0
Benzamide, 3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-N-(1,1-dimethylethyl)-4-propoxy-
CAS 66975-70-0C18H22N6O3
Propanedioic acid, (((3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-methoxyphenyl)amino)methylene)-, diethyl ester chemical structure, C19H20N6O6, CAS 66975-63-1
Propanedioic acid, (((3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-methoxyphenyl)amino)methylene)-, diethyl ester
CAS 66975-63-1C19H20N6O6
Urea, N-(3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)-N'-(1-methylethyl)- chemical structure, C17H21N7O3, CAS 66975-71-1
Urea, N-(3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)-N'-(1-methylethyl)-
CAS 66975-71-1C17H21N7O3
Thiourea, N-(3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)-N'-propyl- chemical structure, C17H21N7O2S, CAS 66975-74-4
Thiourea, N-(3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl)-4-propoxyphenyl)-N'-propyl-
CAS 66975-74-4C17H21N7O2S
3-Ethyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol chemical structure, C12H11N5O, CAS 1071944-53-0
3-Ethyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
CAS 1071944-53-0C12H11N5O
5-Phenyl-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one chemical structure, C10H7N5O, CAS 37761-96-9
5-Phenyl-2,6-dihydrotriazolo[4,5-d]pyrimidin-7-one
CAS 37761-96-9C10H7N5O
5-(5-tert-Butoxy-2-methoxyphenyl)-1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one chemical structure, C15H17N5O3, CAS 128429-39-0
5-(5-tert-Butoxy-2-methoxyphenyl)-1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
CAS 128429-39-0C15H17N5O3
3-Methyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol chemical structure, C11H9N5O, CAS 655241-87-5
3-Methyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol
CAS 655241-87-5C11H9N5O