CompoundList
Sign in
Murcko scaffold

4-(Pyrrolidin-2-yl)thiazole scaffold

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
37
With full pages
5
Scaffold SMILES

c1nc(C2CCCN2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyrrolidin-2-yl)thiazole page
Murcko scaffold c1nc(C2CCCN2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

4-(Pyrrolidin-2-yl)thiazole chemical structure, C7H10N2S, CAS 1190702-11-4
4-(Pyrrolidin-2-yl)thiazole
CAS 1190702-11-4C7H10N2S
tert-Butyl (2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O2S, CAS 871716-68-6
tert-Butyl (2R)-2-(2-amino-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate
CAS 871716-68-6C12H19N3O2S
(S)-tert-Butyl 2-(2-aminothiazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O2S, CAS 887475-97-0
(S)-tert-Butyl 2-(2-aminothiazol-4-yl)pyrrolidine-1-carboxylate
CAS 887475-97-0C12H19N3O2S
tert-Butyl 2-(2-aminothiazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C12H19N3O2S, CAS 1108713-00-3
tert-Butyl 2-(2-aminothiazol-4-yl)pyrrolidine-1-carboxylate
CAS 1108713-00-3C12H19N3O2S
2-Methyl-4-((2S)-pyrrolidin-2-yl)-1,3-thiazole chemical structure, C8H12N2S, CAS 1272743-51-7
2-Methyl-4-((2S)-pyrrolidin-2-yl)-1,3-thiazole
CAS 1272743-51-7C8H12N2S
2-Methyl-4-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C8H12N2S, CAS 1083368-78-8
2-Methyl-4-(pyrrolidin-2-yl)-1,3-thiazole
CAS 1083368-78-8C8H12N2S
(R)-tert-Butyl 2-(2-(methylamino)thiazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C13H21N3O2S, CAS 871727-59-2
(R)-tert-Butyl 2-(2-(methylamino)thiazol-4-yl)pyrrolidine-1-carboxylate
CAS 871727-59-2C13H21N3O2S
4-[(2R)-Pyrrolidin-2-yl]-1,3-thiazol-2-amine chemical structure, C7H11N3S, CAS 1057399-02-6
4-[(2R)-Pyrrolidin-2-yl]-1,3-thiazol-2-amine
CAS 1057399-02-6C7H11N3S
(S)-N-Methyl-4-(pyrrolidin-2-yl)thiazol-2-amine hydrochloride chemical structure, C8H14ClN3S, CAS 1359658-56-2
(S)-N-Methyl-4-(pyrrolidin-2-yl)thiazol-2-amine hydrochloride
CAS 1359658-56-2C8H14ClN3S
2-Thiazolamine, N-methyl-4-(2S)-2-pyrrolidinyl- chemical structure, C8H13N3S, CAS 1359818-62-4
2-Thiazolamine, N-methyl-4-(2S)-2-pyrrolidinyl-
CAS 1359818-62-4C8H13N3S
2-Methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole chemical structure, C8H12N2S, CAS 1272728-02-5
2-Methyl-4-[(2R)-pyrrolidin-2-yl]-1,3-thiazole
CAS 1272728-02-5C8H12N2S
2-(Methoxymethyl)-4-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C9H14N2OS, CAS 1368755-01-4
2-(Methoxymethyl)-4-(pyrrolidin-2-yl)-1,3-thiazole
CAS 1368755-01-4C9H14N2OS
2-(Propan-2-yl)-4-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C10H16N2S, CAS 1521460-42-3
2-(Propan-2-yl)-4-(pyrrolidin-2-yl)-1,3-thiazole
CAS 1521460-42-3C10H16N2S
4-[(2S)-Pyrrolidin-2-yl]-1,3-thiazol-2-amine chemical structure, C7H11N3S, CAS 1344403-75-3
4-[(2S)-Pyrrolidin-2-yl]-1,3-thiazol-2-amine
CAS 1344403-75-3C7H11N3S
2-Bromo-4-(pyrrolidin-2-yl)-1,3-thiazole chemical structure, C7H9BrN2S, CAS 1897838-04-8
2-Bromo-4-(pyrrolidin-2-yl)-1,3-thiazole
CAS 1897838-04-8C7H9BrN2S
1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)pyrrolidin-3-amine chemical structure, C9H15N3S, CAS 1592884-14-4
1-Methyl-2-(2-methyl-1,3-thiazol-4-yl)pyrrolidin-3-amine
CAS 1592884-14-4C9H15N3S
1-Ethyl-2-(1,3-thiazol-4-yl)pyrrolidin-3-amine chemical structure, C9H15N3S, CAS 1601104-26-0
1-Ethyl-2-(1,3-thiazol-4-yl)pyrrolidin-3-amine
CAS 1601104-26-0C9H15N3S
2-Methyl-4-[(2R)-1-(prop-2-yn-1-yl)pyrrolidin-2-yl]-1,3-thiazole chemical structure, C11H14N2S, CAS 2093476-09-4
2-Methyl-4-[(2R)-1-(prop-2-yn-1-yl)pyrrolidin-2-yl]-1,3-thiazole
CAS 2093476-09-4C11H14N2S
1-Methyl-2-(1,3-thiazol-4-yl)pyrrolidin-3-amine chemical structure, C8H13N3S, CAS 1593847-97-2
1-Methyl-2-(1,3-thiazol-4-yl)pyrrolidin-3-amine
CAS 1593847-97-2C8H13N3S
2-Chloro-1-[(2R)-2-(2-methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]propan-1-one chemical structure, C11H15ClN2OS, CAS 2411183-69-0
2-Chloro-1-[(2R)-2-(2-methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]propan-1-one
CAS 2411183-69-0C11H15ClN2OS
1-[2-(2-Methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]prop-2-en-1-one chemical structure, C11H14N2OS, CAS 2384583-24-6
1-[2-(2-Methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]prop-2-en-1-one
CAS 2384583-24-6C11H14N2OS
rac-(2R,3R)-1-(Propan-2-yl)-2-[2-(propan-2-yl)-1,3-thiazol-4-yl]pyrrolidin-3-amine chemical structure, C13H23N3S, CAS 2227644-27-9
rac-(2R,3R)-1-(Propan-2-yl)-2-[2-(propan-2-yl)-1,3-thiazol-4-yl]pyrrolidin-3-amine
CAS 2227644-27-9C13H23N3S
1-[(2S)-2-(2-Methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]prop-2-en-1-one chemical structure, C11H14N2OS, CAS 2308274-60-2
1-[(2S)-2-(2-Methyl-1,3-thiazol-4-yl)pyrrolidin-1-yl]prop-2-en-1-one
CAS 2308274-60-2C11H14N2OS
tert-Butyl (2S)-2-(2-bromo-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate chemical structure, C12H17BrN2O2S, CAS 2869877-82-5
tert-Butyl (2S)-2-(2-bromo-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate
CAS 2869877-82-5C12H17BrN2O2S