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Murcko scaffold

2,3-Diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione scaffold

38 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 38
With full pages: 5

Scaffold SMILES

O=C1NC(=O)C2C1ON(c1ccccc1)C2c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2,3-Diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione page

Murcko scaffold O=C1NC(=O)C2C1ON(c1ccccc1)C2c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

2-(4-Chlorophenyl)-3-(4-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C18H15ClN2O4, CAS 474004-98-3

2-(4-Chlorophenyl)-3-(4-methoxyphenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 474004-98-3C₁₈H₁₅ClN₂O₄

3-(4-Fluoro-phenyl)-2-phenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione chemical structure, C17H13FN2O3, CAS 474005-31-7

3-(4-Fluoro-phenyl)-2-phenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione

CAS 474005-31-7C₁₇H₁₃FN₂O₃

3-(4-Methoxy-phenyl)-2-phenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione chemical structure, C18H16N2O4, CAS 1005262-43-0

3-(4-Methoxy-phenyl)-2-phenyl-tetrahydro-pyrrolo[3,4-d]isoxazole-4,6-dione

CAS 1005262-43-0C₁₈H₁₆N₂O₄

5-Butyl-2-(4-chlorophenyl)-3-(3-nitrophenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C21H20ClN3O5, CAS 1005262-61-2

5-Butyl-2-(4-chlorophenyl)-3-(3-nitrophenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005262-61-2C₂₁H₂₀ClN₃O₅

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C19H18ClN3O3, CAS 474092-42-7

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 474092-42-7C₁₉H₁₈ClN₃O₃

2-(4-Chlorophenyl)-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C17H13ClN2O3, CAS 1005117-43-0

2-(4-Chlorophenyl)-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005117-43-0C₁₇H₁₃ClN₂O₃

5-Butyl-3-(2,4-dimethoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C23H26N2O5, CAS 474255-25-9

5-Butyl-3-(2,4-dimethoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 474255-25-9C₂₃H₂₆N₂O₅

5-Ethyl-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C20H20N2O4, CAS 474260-72-5

5-Ethyl-3-(4-methoxyphenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 474260-72-5C₂₀H₂₀N₂O₄

3-(2,4-Dimethoxyphenyl)-2-phenyl-5-propan-2-yl-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione chemical structure, C22H24N2O5, CAS 474262-13-0

3-(2,4-Dimethoxyphenyl)-2-phenyl-5-propan-2-yl-3a,6a-dihydro-3H-pyrrolo[3,4-d][1,2]oxazole-4,6-dione

CAS 474262-13-0C₂₂H₂₄N₂O₅

Methyl 4-(2-(4-bromophenyl)-4,6-dioxohexahydro-2H-pyrrolo[3,4-d]isoxazol-3-yl)benzoate chemical structure, C19H15BrN2O5, CAS 1005069-19-1

Methyl 4-(2-(4-bromophenyl)-4,6-dioxohexahydro-2H-pyrrolo[3,4-d]isoxazol-3-yl)benzoate

CAS 1005069-19-1C₁₉H₁₅BrN₂O₅

3-(4-Chlorophenyl)-2-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C18H15ClN2O3, CAS 1005122-98-4

3-(4-Chlorophenyl)-2-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005122-98-4C₁₈H₁₅ClN₂O₃

3-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-5-propyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione chemical structure, C21H22N2O5, CAS 1005108-57-5

3-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-5-propyldihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione

CAS 1005108-57-5C₂₁H₂₂N₂O₅

3-(4-Fluorophenyl)-5-(2-methoxyethyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C20H19FN2O4, CAS 1005127-21-8

3-(4-Fluorophenyl)-5-(2-methoxyethyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005127-21-8C₂₀H₁₉FN₂O₄

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-5-isopropyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C22H24ClN3O3, CAS 1005060-25-2

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-5-isopropyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005060-25-2C₂₂H₂₄ClN₃O₃

2-(4-Chlorophenyl)-5-isopropyl-3-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C21H21ClN2O3, CAS 1005060-26-3

2-(4-Chlorophenyl)-5-isopropyl-3-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005060-26-3C₂₁H₂₁ClN₂O₃

2-(4-Chlorophenyl)-3-{4-nitrophenyl}-5-methyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione chemical structure, C18H14ClN3O5, CAS 1005273-08-4

2-(4-Chlorophenyl)-3-{4-nitrophenyl}-5-methyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(3H,5H)-dione

CAS 1005273-08-4C₁₈H₁₄ClN₃O₅

2-(4-Chlorophenyl)-3-(4-methylphenyl)dihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione chemical structure, C18H15ClN2O3, CAS 1005055-69-5

2-(4-Chlorophenyl)-3-(4-methylphenyl)dihydro-2H-pyrrolo[3,4-d][1,2]oxazole-4,6(3H,5H)-dione

CAS 1005055-69-5C₁₈H₁₅ClN₂O₃

5-Butyl-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C23H27N3O3, CAS 1005060-70-7

5-Butyl-3-(4-(dimethylamino)phenyl)-2-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005060-70-7C₂₃H₂₇N₃O₃

2,3-Diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C17H14N2O3, CAS 1212396-81-0

2,3-Diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1212396-81-0C₁₇H₁₄N₂O₃

5-Methyl-2,3-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C18H16N2O3, CAS 1005060-84-3

5-Methyl-2,3-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005060-84-3C₁₈H₁₆N₂O₃

5-Methyl-2-phenyl-3-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C19H18N2O3, CAS 1005116-95-9

5-Methyl-2-phenyl-3-(p-tolyl)dihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005116-95-9C₁₉H₁₈N₂O₃

5-Butyl-2-(4-chlorophenyl)-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C21H21ClN2O3, CAS 1005052-86-7

5-Butyl-2-(4-chlorophenyl)-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005052-86-7C₂₁H₂₁ClN₂O₃

2-(4-Chlorophenyl)-5-isopropyl-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C20H19ClN2O3, CAS 1005134-38-2

2-(4-Chlorophenyl)-5-isopropyl-3-phenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005134-38-2C₂₀H₁₉ClN₂O₃

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-5-ethyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione chemical structure, C21H22ClN3O3, CAS 1005086-15-6

2-(4-Chlorophenyl)-3-(4-(dimethylamino)phenyl)-5-ethyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione

CAS 1005086-15-6C₂₁H₂₂ClN₃O₃