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Murcko scaffold

Ring system with 4 rings and 20 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
15
With full pages
3
Scaffold SMILES

c1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nc3n(c2-c2ccncc2)CCC3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

SK&F 104351 chemical structure, C17H14FN3, CAS 111908-94-2
SK&F 104351
CAS 111908-94-2C17H14FN3
SK&F 105561 chemical structure, C18H17N3S, CAS 122454-68-6
SK&F 105561
CAS 122454-68-6C18H17N3S
SK&F 105809 chemical structure, C18H17N3OS, CAS 122454-69-7
SK&F 105809
CAS 122454-69-7C18H17N3OS
2-(4-Methoxyphenyl)-3-(4-pyridyl)-6,7-dihydro-(5H)-pyrrolo(1,2-a)imidazole chemical structure, C18H17N3O, CAS 111908-95-3
2-(4-Methoxyphenyl)-3-(4-pyridyl)-6,7-dihydro-(5H)-pyrrolo(1,2-a)imidazole
CAS 111908-95-3C18H17N3O
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylsulfinyl)phenyl]-6,7-dihydro-3-(4-pyridinyl)- chemical structure, C19H19N3OS, CAS 122454-61-9
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylsulfinyl)phenyl]-6,7-dihydro-3-(4-pyridinyl)-
CAS 122454-61-9C19H19N3OS
3-(2-Methyl-4-pyridyl)-2-(4-methylsulfanylphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole chemical structure, C19H19N3S, CAS 122454-78-8
3-(2-Methyl-4-pyridyl)-2-(4-methylsulfanylphenyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole
CAS 122454-78-8C19H19N3S
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylsulfonyl)phenyl]-6,7-dihydro-3-(4-pyridinyl)- chemical structure, C19H19N3O2S, CAS 122454-64-2
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylsulfonyl)phenyl]-6,7-dihydro-3-(4-pyridinyl)-
CAS 122454-64-2C19H19N3O2S
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylthio)phenyl]-6,7-dihydro-3-(4-pyridinyl)- chemical structure, C19H19N3S, CAS 122454-62-0
5H-Pyrrolo[1,2-a]imidazole,2-[4-(ethylthio)phenyl]-6,7-dihydro-3-(4-pyridinyl)-
CAS 122454-62-0C19H19N3S
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-(1-methylethoxy)phenyl]-3-(4-pyridinyl)- chemical structure, C20H21N3O, CAS 122454-60-8
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-(1-methylethoxy)phenyl]-3-(4-pyridinyl)-
CAS 122454-60-8C20H21N3O
5H-Pyrrolo[1,2-a]imidazole,2-(4-ethoxyphenyl)-6,7-dihydro-3-(4-pyridinyl)- chemical structure, C19H19N3O, CAS 122454-58-4
5H-Pyrrolo[1,2-a]imidazole,2-(4-ethoxyphenyl)-6,7-dihydro-3-(4-pyridinyl)-
CAS 122454-58-4C19H19N3O
5H-Pyrrolo[1,2-a]imidazole,3-(2,6-dimethyl-4-pyridinyl)-6,7-dihydro-2-(4-methoxyphenyl)- chemical structure, C20H21N3O, CAS 122454-56-2
5H-Pyrrolo[1,2-a]imidazole,3-(2,6-dimethyl-4-pyridinyl)-6,7-dihydro-2-(4-methoxyphenyl)-
CAS 122454-56-2C20H21N3O
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-[(2-methyl-1-propenyl)thio]phenyl]-3-(4-pyridinyl)- chemical structure, C21H21N3S, CAS 122454-72-2
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-[(2-methyl-1-propenyl)thio]phenyl]-3-(4-pyridinyl)-
CAS 122454-72-2C21H21N3S
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-(methylsulfonyl)phenyl]-3-(4-pyridinyl)- chemical structure, C18H17N3O2S, CAS 122454-53-9
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-[4-(methylsulfonyl)phenyl]-3-(4-pyridinyl)-
CAS 122454-53-9C18H17N3O2S
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-(4-propoxyphenyl)-3-(4-pyridinyl)- chemical structure, C20H21N3O, CAS 122454-59-5
5H-Pyrrolo[1,2-a]imidazole,6,7-dihydro-2-(4-propoxyphenyl)-3-(4-pyridinyl)-
CAS 122454-59-5C20H21N3O
5H-Pyrrolo[1,2-a]imidazole,2-(4-fluorophenyl)-6,7-dihydro-3-(2-methyl-4-pyridinyl)- chemical structure, C18H16FN3, CAS 122454-77-7
5H-Pyrrolo[1,2-a]imidazole,2-(4-fluorophenyl)-6,7-dihydro-3-(2-methyl-4-pyridinyl)-
CAS 122454-77-7C18H16FN3