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Murcko scaffold

Hypoxanthine, 9-benzyl- scaffold

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
27
With full pages
5
Scaffold SMILES

O=c1[nH]cnc2c1ncn2Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Hypoxanthine, 9-benzyl- page
Murcko scaffold O=c1[nH]cnc2c1ncn2Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

9-Benzyl-2-chloro-9H-purin-6-ol chemical structure, C12H9ClN4O, CAS 95194-86-8
9-Benzyl-2-chloro-9H-purin-6-ol
CAS 95194-86-8C12H9ClN4O
8-Amino-9-benzylguanine chemical structure, C12H12N6O, CAS 100890-94-6
8-Amino-9-benzylguanine
CAS 100890-94-6C12H12N6O
9-Benzylguanine chemical structure, C12H11N5O, CAS 14937-72-5
9-Benzylguanine
CAS 14937-72-5C12H11N5O
Hypoxanthine, 9-benzyl- chemical structure, C12H10N4O, CAS 14013-11-7
Hypoxanthine, 9-benzyl-
CAS 14013-11-7C12H10N4O
9-[(2-Chlorophenyl)methyl]-3H-purin-6-one chemical structure, C12H9ClN4O, CAS 34396-87-7
9-[(2-Chlorophenyl)methyl]-3H-purin-6-one
CAS 34396-87-7C12H9ClN4O
2-Amino-9-(2-chlorobenzyl)-3,9-dihydro-6H-purin-6-one chemical structure, C12H10ClN5O, CAS 17756-37-5
2-Amino-9-(2-chlorobenzyl)-3,9-dihydro-6H-purin-6-one
CAS 17756-37-5C12H10ClN5O
2-Amino-9-(4-chlorobenzyl)-1H-purin-6(9H)-one chemical structure, C12H10ClN5O, CAS 14937-73-6
2-Amino-9-(4-chlorobenzyl)-1H-purin-6(9H)-one
CAS 14937-73-6C12H10ClN5O
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-(phenylmethyl)- chemical structure, C12H10BrN5O, CAS 96412-45-2
6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-(phenylmethyl)-
CAS 96412-45-2C12H10BrN5O
6-Hydroxy-9-(4-aminobenzyl)purine chemical structure, C12H11N5O, CAS 75207-04-4
6-Hydroxy-9-(4-aminobenzyl)purine
CAS 75207-04-4C12H11N5O
9H-Purin-6-ol, 9-(p-nitrobenzyl)- chemical structure, C12H9N5O3, CAS 13233-86-8
9H-Purin-6-ol, 9-(p-nitrobenzyl)-
CAS 13233-86-8C12H9N5O3
9H-Purin-6(1H)-one, 9-benzyl-2-dimethylamino- chemical structure, C14H15N5O, CAS 7461-80-5
9H-Purin-6(1H)-one, 9-benzyl-2-dimethylamino-
CAS 7461-80-5C14H15N5O
Methyl 4-[(6-oxo-1H-purin-9-yl)methyl]benzoate chemical structure, C14H12N4O3, CAS 92150-24-8
Methyl 4-[(6-oxo-1H-purin-9-yl)methyl]benzoate
CAS 92150-24-8C14H12N4O3
4-[(6-Oxo-3,6-dihydro-9H-purin-9-yl)methyl]benzoic acid chemical structure, C13H10N4O3, CAS 34397-05-2
4-[(6-Oxo-3,6-dihydro-9H-purin-9-yl)methyl]benzoic acid
CAS 34397-05-2C13H10N4O3
9-[(3-Chlorophenyl)methyl]-1H-purin-6-one chemical structure, C12H9ClN4O, CAS 34396-86-6
9-[(3-Chlorophenyl)methyl]-1H-purin-6-one
CAS 34396-86-6C12H9ClN4O
4-[(6-Oxo-3,6-dihydro-9H-purin-9-yl)methyl]benzenesulfonamide chemical structure, C12H11N5O3S, CAS 21267-97-0
4-[(6-Oxo-3,6-dihydro-9H-purin-9-yl)methyl]benzenesulfonamide
CAS 21267-97-0C12H11N5O3S
9-[(2,5-Dimethylphenyl)methyl]-3H-purin-6-one chemical structure, C14H14N4O, CAS 34396-95-7
9-[(2,5-Dimethylphenyl)methyl]-3H-purin-6-one
CAS 34396-95-7C14H14N4O
Mdl 74428 chemical structure, C14H14N5O4P, CAS 139981-26-3
Mdl 74428
CAS 139981-26-3C14H14N5O4P
9-(1-Phenylethyl)-3,9-dihydro-6H-purin-6-one chemical structure, C13H12N4O, CAS 34396-98-0
9-(1-Phenylethyl)-3,9-dihydro-6H-purin-6-one
CAS 34396-98-0C13H12N4O
2-Amino-8-bromo-9-(4-fluorobenzyl)-1,9-dihydro-6H-purin-6-one chemical structure, C12H9BrFN5O, CAS 101134-23-0
2-Amino-8-bromo-9-(4-fluorobenzyl)-1,9-dihydro-6H-purin-6-one
CAS 101134-23-0C12H9BrFN5O
2-Amino-9-[(4-fluorophenyl)methyl]-1H-purin-6-one chemical structure, C12H10FN5O, CAS 101134-17-2
2-Amino-9-[(4-fluorophenyl)methyl]-1H-purin-6-one
CAS 101134-17-2C12H10FN5O
Halo PROTAC 1 chemical structure, C33H49Cl2N7O8S, CAS 2241668-45-9
Halo PROTAC 1
CAS 2241668-45-9C33H49Cl2N7O8S
E3 ligase Ligand 18 chemical structure, C17H17ClN6O4S, CAS 2241669-88-3
E3 ligase Ligand 18
CAS 2241669-88-3C17H17ClN6O4S
Mitochondria degrader-1 chemical structure, C33H49ClFN7O8S, CAS 2241669-05-4
Mitochondria degrader-1
CAS 2241669-05-4C33H49ClFN7O8S
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 chemical structure, C27H39FN8O6S, CAS 2241669-84-9
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
CAS 2241669-84-9C27H39FN8O6S