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Murcko scaffold

3-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one scaffold

93 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
93
With full pages
19
Scaffold SMILES

O=c1[nH]nc(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one page
Murcko scaffold O=c1[nH]nc(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 93 chemicals

Mdl-27192 chemical structure, C10H10ClN3O, CAS 31409-32-2
Mdl-27192
CAS 31409-32-2C10H10ClN3O
Mdl 27266 chemical structure, C11H12ClN3O, CAS 116114-14-8
Mdl 27266
CAS 116114-14-8C11H12ClN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-phenyl- chemical structure, C10H11N3O, CAS 944-91-2
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-phenyl-
CAS 944-91-2C10H11N3O
4-Ethyl-2,4-dihydro-2-methyl-5-phenyl-3H-1,2,4-triazol-3-one chemical structure, C11H13N3O, CAS 947-85-3
4-Ethyl-2,4-dihydro-2-methyl-5-phenyl-3H-1,2,4-triazol-3-one
CAS 947-85-3C11H13N3O
4-Amino-3-phenyl-1H-1,2,4-triazol-5-one chemical structure, C8H8N4O, CAS 57735-10-1
4-Amino-3-phenyl-1H-1,2,4-triazol-5-one
CAS 57735-10-1C8H8N4O
4-Amino-N,N-dimethyl-5-oxo-3-phenyl-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide chemical structure, C11H13N5O2, CAS 73324-36-4
4-Amino-N,N-dimethyl-5-oxo-3-phenyl-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
CAS 73324-36-4C11H13N5O2
3-(4-Fluorophenyl)-4-propyl-4,5-dihydro-1H-1,2,4-triazol-5-one chemical structure, C11H12FN3O, CAS 271798-52-8
3-(4-Fluorophenyl)-4-propyl-4,5-dihydro-1H-1,2,4-triazol-5-one
CAS 271798-52-8C11H12FN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-methyl-5-phenyl- chemical structure, C9H9N3O, CAS 50369-39-6
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-methyl-5-phenyl-
CAS 50369-39-6C9H9N3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-methyl-5-(3,4,5-trimethoxyphenyl)- chemical structure, C12H15N3O4, CAS 108132-87-2
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-methyl-5-(3,4,5-trimethoxyphenyl)-
CAS 108132-87-2C12H15N3O4
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-ethoxy-3,5-dimethoxyphenyl)-4-methyl- chemical structure, C13H17N3O4, CAS 108132-89-4
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-ethoxy-3,5-dimethoxyphenyl)-4-methyl-
CAS 108132-89-4C13H17N3O4
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-5-(3,4,5-trimethoxyphenyl)- chemical structure, C13H17N3O4, CAS 108132-90-7
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-5-(3,4,5-trimethoxyphenyl)-
CAS 108132-90-7C13H17N3O4
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-ethoxy-3,5-dimethoxyphenyl)-4-ethyl- chemical structure, C14H19N3O4, CAS 108132-92-9
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-ethoxy-3,5-dimethoxyphenyl)-4-ethyl-
CAS 108132-92-9C14H19N3O4
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-5-(3-(trifluoromethyl)phenyl)- chemical structure, C11H10F3N3O, CAS 129521-48-8
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-5-(3-(trifluoromethyl)phenyl)-
CAS 129521-48-8C11H10F3N3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-methoxyphenyl)-4-methyl- chemical structure, C10H11N3O2, CAS 129521-49-9
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-methoxyphenyl)-4-methyl-
CAS 129521-49-9C10H11N3O2
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-2-methyl-5-(3-(trifluoromethyl)phenyl)- chemical structure, C12H12F3N3O, CAS 129521-50-2
3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-ethyl-2-methyl-5-(3-(trifluoromethyl)phenyl)-
CAS 129521-50-2C12H12F3N3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-(4-methoxyphenyl)- chemical structure, C11H13N3O2, CAS 129521-51-3
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-(4-methoxyphenyl)-
CAS 129521-51-3C11H13N3O2
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2-ethyl-4-methyl- chemical structure, C11H12ClN3O, CAS 114058-88-7
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2-ethyl-4-methyl-
CAS 114058-88-7C11H12ClN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2-ethyl-4-methyl-5-phenyl- chemical structure, C11H13N3O, CAS 116114-12-6
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2-ethyl-4-methyl-5-phenyl-
CAS 116114-12-6C11H13N3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2,4-dimethyl- chemical structure, C10H10ClN3O, CAS 116114-13-7
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2,4-dimethyl-
CAS 116114-13-7C10H10ClN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2,4-diethyl- chemical structure, C12H14ClN3O, CAS 116114-15-9
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-2,4-diethyl-
CAS 116114-15-9C12H14ClN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-(4-fluorophenyl)- chemical structure, C10H10FN3O, CAS 116114-16-0
3H-1,2,4-Triazol-3-one, 2,4-dihydro-2,4-dimethyl-5-(4-fluorophenyl)-
CAS 116114-16-0C10H10FN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-4-methyl- chemical structure, C9H8ClN3O, CAS 116114-20-6
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-chlorophenyl)-4-methyl-
CAS 116114-20-6C9H8ClN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-fluorophenyl)-4-methyl- chemical structure, C9H8FN3O, CAS 116114-21-7
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(4-fluorophenyl)-4-methyl-
CAS 116114-21-7C9H8FN3O
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(2-chlorophenyl)-4-methyl- chemical structure, C9H8ClN3O, CAS 117258-16-9
3H-1,2,4-Triazol-3-one, 2,4-dihydro-5-(2-chlorophenyl)-4-methyl-
CAS 117258-16-9C9H8ClN3O