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Murcko scaffold

2-Morpholinopyrazine scaffold

73 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
73
With full pages
5
Scaffold SMILES

c1cnc(N2CCOCC2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Morpholinopyrazine page
Murcko scaffold c1cnc(N2CCOCC2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 73 chemicals

Pyrazinecarbothioamide, 6-(4-morpholinyl)- chemical structure, C9H12N4OS, CAS 61689-90-5
Pyrazinecarbothioamide, 6-(4-morpholinyl)-
CAS 61689-90-5C9H12N4OS
6-Morpholin-4-ylpyrazine-2-carboxylic acid chemical structure, C9H11N3O3, CAS 40262-73-5
6-Morpholin-4-ylpyrazine-2-carboxylic acid
CAS 40262-73-5C9H11N3O3
Methyl 3-amino-6-chloro-5-morpholinopyrazine-2-carboxylate chemical structure, C10H13ClN4O3, CAS 27282-34-4
Methyl 3-amino-6-chloro-5-morpholinopyrazine-2-carboxylate
CAS 27282-34-4C10H13ClN4O3
6-(Morpholin-4-yl)pyrazine-2-carbonitrile chemical structure, C9H10N4O, CAS 40262-52-0
6-(Morpholin-4-yl)pyrazine-2-carbonitrile
CAS 40262-52-0C9H10N4O
Pyrazinecarbothioamide, N-[(diethylamino)methyl]-6-(4-morpholinyl)- chemical structure, C14H23N5OS, CAS 61689-84-7
Pyrazinecarbothioamide, N-[(diethylamino)methyl]-6-(4-morpholinyl)-
CAS 61689-84-7C14H23N5OS
Pyrazinecarbothioamide, N-(hydroxymethyl)-6-(4-morpholinyl)- chemical structure, C10H14N4O2S, CAS 61689-89-2
Pyrazinecarbothioamide, N-(hydroxymethyl)-6-(4-morpholinyl)-
CAS 61689-89-2C10H14N4O2S
2-Morpholinopyrazine chemical structure, C8H11N3O, CAS 5625-94-5
2-Morpholinopyrazine
CAS 5625-94-5C8H11N3O
4-(3,5-Dibromo-2-pyrazinyl)morpholine chemical structure, C8H9Br2N3O, CAS 84539-08-2
4-(3,5-Dibromo-2-pyrazinyl)morpholine
CAS 84539-08-2C8H9Br2N3O
5-Chloro-6-(morpholin-4-yl)-3-nitropyrazin-2-amine chemical structure, C8H10ClN5O3, CAS 88793-47-9
5-Chloro-6-(morpholin-4-yl)-3-nitropyrazin-2-amine
CAS 88793-47-9C8H10ClN5O3
5,6-Dichloro-3-morpholin-4-ylpyrazine-2-carbonitrile chemical structure, C9H8Cl2N4O, CAS 90601-38-0
5,6-Dichloro-3-morpholin-4-ylpyrazine-2-carbonitrile
CAS 90601-38-0C9H8Cl2N4O
6-Chloro-5-methylsulfanyl-3-morpholin-4-ylpyrazine-2-carbonitrile chemical structure, C10H11ClN4OS, CAS 90601-39-1
6-Chloro-5-methylsulfanyl-3-morpholin-4-ylpyrazine-2-carbonitrile
CAS 90601-39-1C10H11ClN4OS
5,6-Dichloro-3-(morpholin-4-yl)pyrazine-2-carbaldehyde chemical structure, C9H9Cl2N3O2, CAS 90601-45-9
5,6-Dichloro-3-(morpholin-4-yl)pyrazine-2-carbaldehyde
CAS 90601-45-9C9H9Cl2N3O2
6-Chloro-5-(dimethylamino)-3-morpholin-4-ylpyrazine-2-carbaldehyde chemical structure, C11H15ClN4O2, CAS 90601-47-1
6-Chloro-5-(dimethylamino)-3-morpholin-4-ylpyrazine-2-carbaldehyde
CAS 90601-47-1C11H15ClN4O2
6-Chloro-5-methylsulfanyl-3-morpholin-4-ylpyrazine-2-carbaldehyde chemical structure, C10H12ClN3O2S, CAS 90601-48-2
6-Chloro-5-methylsulfanyl-3-morpholin-4-ylpyrazine-2-carbaldehyde
CAS 90601-48-2C10H12ClN3O2S
6-(Morpholin-4-yl)pyrazine-2-carbohydrazide chemical structure, C9H13N5O2, CAS 40262-76-8
6-(Morpholin-4-yl)pyrazine-2-carbohydrazide
CAS 40262-76-8C9H13N5O2
3-Morpholinopyrazine-2-carbonitrile chemical structure, C9H10N4O, CAS 67130-86-3
3-Morpholinopyrazine-2-carbonitrile
CAS 67130-86-3C9H10N4O
3-Morpholin-4-ylpyrazine-2-carboxylic acid chemical structure, C9H11N3O3, CAS 342425-64-3
3-Morpholin-4-ylpyrazine-2-carboxylic acid
CAS 342425-64-3C9H11N3O3
3-(4-Morpholinyl)-2-pyrazinecarbothioamide chemical structure, C9H12N4OS, CAS 342425-65-4
3-(4-Morpholinyl)-2-pyrazinecarbothioamide
CAS 342425-65-4C9H12N4OS
5-Bromo-3-morpholinopyrazin-2-amine chemical structure, C8H11BrN4O, CAS 117719-17-2
5-Bromo-3-morpholinopyrazin-2-amine
CAS 117719-17-2C8H11BrN4O
4-(3-Chloropyrazin-2-yl)morpholine chemical structure, C8H10ClN3O, CAS 54126-40-8
4-(3-Chloropyrazin-2-yl)morpholine
CAS 54126-40-8C8H10ClN3O
4-(6-Chloropyrazin-2-yl)morpholine chemical structure, C8H10ClN3O, CAS 720693-19-6
4-(6-Chloropyrazin-2-yl)morpholine
CAS 720693-19-6C8H10ClN3O
2-Amino-3-morpholin-4-ylpyrazine chemical structure, C8H12N4O, CAS 117719-16-1
2-Amino-3-morpholin-4-ylpyrazine
CAS 117719-16-1C8H12N4O
6-Morpholinopyrazine-2-boronic acid chemical structure, C8H12BN3O3, CAS 1310383-62-0
6-Morpholinopyrazine-2-boronic acid
CAS 1310383-62-0C8H12BN3O3
4-(5-Bromopyrazin-2-yl)morpholine chemical structure, C8H10BrN3O, CAS 955050-08-5
4-(5-Bromopyrazin-2-yl)morpholine
CAS 955050-08-5C8H10BrN3O