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Murcko scaffold

Ring system with 3 rings and 15 atoms

27 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 15
Chemicals: 27
With full pages: 5

Scaffold SMILES

c1ccc(C2=Nn3cnnc3SC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(C2=Nn3cnnc3SC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

6-(4-Chloro-phenyl)-3-pentyl-7H-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazine chemical structure, C15H17ClN4S, CAS 86628-12-8

6-(4-Chloro-phenyl)-3-pentyl-7H-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazine

CAS 86628-12-8C₁₅H₁₇ClN₄S

1,2,3-Benzenetriol, 4-(3-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazin-6-yl)-, monohydrochloride chemical structure, C11H11ClN4O3S, CAS 69560-92-5

1,2,3-Benzenetriol, 4-(3-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazin-6-yl)-, monohydrochloride

CAS 69560-92-5C₁₁H₁₁ClN₄O₃S

6-(4-Chlorophenyl)-3-methyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H9ClN4S, CAS 54025-90-0

6-(4-Chlorophenyl)-3-methyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 54025-90-0C₁₁H₉ClN₄S

6-(3,4-Dimethoxyphenyl)-3-ethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C14H16N4O2S, CAS 442669-13-8

6-(3,4-Dimethoxyphenyl)-3-ethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 442669-13-8C₁₄H₁₆N₄O₂S

[6-(4-Chlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methanol chemical structure, C11H9ClN4OS, CAS 632292-55-8

[6-(4-Chlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methanol

CAS 632292-55-8C₁₁H₉ClN₄OS

6-(4-Chlorophenyl)-3-isopropyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C13H13ClN4S, CAS 890603-69-7

6-(4-Chlorophenyl)-3-isopropyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 890603-69-7C₁₃H₁₃ClN₄S

RefChem:381569 chemical structure, C10H7ClN4S, CAS 62467-76-9

CAS 62467-76-9C₁₀H₇ClN₄S

6-(4-Nitrophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C10H7N5O2S, CAS 22184-42-5

6-(4-Nitrophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 22184-42-5C₁₀H₇N₅O₂S

3-Methyl-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H10N4S, CAS 54025-94-4

3-Methyl-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 54025-94-4C₁₁H₁₀N₄S

6-(4-Bromophenyl)-3-methyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H9BrN4S, CAS 54025-92-2

6-(4-Bromophenyl)-3-methyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 54025-92-2C₁₁H₉BrN₄S

Phenol, 2,6-bis(1,1-dimethylethyl)-4-(7-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazin-6-yl)- chemical structure, C19H26N4OS, CAS 117829-32-0

Phenol, 2,6-bis(1,1-dimethylethyl)-4-(7-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazin-6-yl)-

CAS 117829-32-0C₁₉H₂₆N₄OS

6-(2,4-Dichlorophenyl)-3-ethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C12H10Cl2N4S, CAS 382595-92-8

6-(2,4-Dichlorophenyl)-3-ethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 382595-92-8C₁₂H₁₀Cl₂N₄S

3-Propan-2-yl-6-(4-propylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C16H20N4S, CAS 753474-01-0

3-Propan-2-yl-6-(4-propylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 753474-01-0C₁₆H₂₀N₄S

6-[4-(Difluoromethoxy)phenyl]-3,7-dimethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C13H12F2N4OS, CAS 851110-45-7

6-[4-(Difluoromethoxy)phenyl]-3,7-dimethyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 851110-45-7C₁₃H₁₂F₂N₄OS

3-(Chlorodifluoromethyl)-6-(2,4-dichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H5Cl3F2N4S, CAS 832739-69-2

3-(Chlorodifluoromethyl)-6-(2,4-dichlorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-69-2C₁₁H₅Cl₃F₂N₄S

3-[Chloro(difluoro)methyl]-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H7ClF2N4S, CAS 832739-98-7

3-[Chloro(difluoro)methyl]-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-98-7C₁₁H₇ClF₂N₄S

3-(Chlorodifluoromethyl)-6-(2,4-difluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H5ClF4N4S, CAS 832739-42-1

3-(Chlorodifluoromethyl)-6-(2,4-difluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-42-1C₁₁H₅ClF₄N₄S

6-(2,4-Dichlorophenyl)-3-(difluoromethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H6Cl2F2N4S, CAS 832739-43-2

6-(2,4-Dichlorophenyl)-3-(difluoromethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-43-2C₁₁H₆Cl₂F₂N₄S

3-(Difluoromethyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H8F2N4S, CAS 832739-49-8

3-(Difluoromethyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-49-8C₁₁H₈F₂N₄S

3-(Difluoromethyl)-6-(2,4-difluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C11H6F4N4S, CAS 832739-32-9

3-(Difluoromethyl)-6-(2,4-difluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 832739-32-9C₁₁H₆F₄N₄S

6-(2,4-Difluorophenyl)-3-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazine chemical structure, C11H8F2N4S, CAS 832737-52-7

6-(2,4-Difluorophenyl)-3-methyl-7H-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazine

CAS 832737-52-7C₁₁H₈F₂N₄S

3-(Methoxymethyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C12H12N4OS, CAS 904504-79-6

3-(Methoxymethyl)-6-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 904504-79-6C₁₂H₁₂N₄OS

6-(4-Chlorophenyl)-3-(methoxymethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C12H11ClN4OS, CAS 903199-87-1

6-(4-Chlorophenyl)-3-(methoxymethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 903199-87-1C₁₂H₁₁ClN₄OS

6-(4-Bromophenyl)-3-(methoxymethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine chemical structure, C12H11BrN4OS, CAS 915878-86-3

6-(4-Bromophenyl)-3-(methoxymethyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

CAS 915878-86-3C₁₂H₁₁BrN₄OS