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Murcko scaffold

N-Phenylthiophene-2-sulfonamide scaffold

306 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
306
With full pages
39
Scaffold SMILES

O=S(=O)(Nc1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenylthiophene-2-sulfonamide page
Murcko scaffold O=S(=O)(Nc1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 306 chemicals

N-(4-Amino-2-hydroxyphenyl)thiophene-2-sulfonamide chemical structure, C10H10N2O3S2, CAS 38880-73-8
N-(4-Amino-2-hydroxyphenyl)thiophene-2-sulfonamide
CAS 38880-73-8C10H10N2O3S2
N-(2,4-Dinitrophenyl)thiophene-2-sulfonamide chemical structure, C10H7N3O6S2, CAS 54087-34-2
N-(2,4-Dinitrophenyl)thiophene-2-sulfonamide
CAS 54087-34-2C10H7N3O6S2
N-(2,5-Dimethoxyphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO4S2, CAS 358666-80-5
N-(2,5-Dimethoxyphenyl)thiophene-2-sulfonamide
CAS 358666-80-5C12H13NO4S2
N-[2-(Trifluoromethyl)phenyl]thiophene-2-sulfonamide chemical structure, C11H8F3NO2S2, CAS 355419-60-2
N-[2-(Trifluoromethyl)phenyl]thiophene-2-sulfonamide
CAS 355419-60-2C11H8F3NO2S2
N-(3-Bromo-4-hydroxyphenyl)thiophene-2-sulfonamide chemical structure, C10H8BrNO3S2, CAS 518053-28-6
N-(3-Bromo-4-hydroxyphenyl)thiophene-2-sulfonamide
CAS 518053-28-6C10H8BrNO3S2
N-(3-Chloro-4-hydroxyphenyl)thiophene-2-sulfonamide chemical structure, C10H8ClNO3S2, CAS 518053-29-7
N-(3-Chloro-4-hydroxyphenyl)thiophene-2-sulfonamide
CAS 518053-29-7C10H8ClNO3S2
N-(2,3-Dimethylphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO2S2, CAS 518305-32-3
N-(2,3-Dimethylphenyl)thiophene-2-sulfonamide
CAS 518305-32-3C12H13NO2S2
N-(4-Methoxyphenyl)-2-methyl-N-thiophen-2-ylsulfonylpropanamide chemical structure, C15H17NO4S2, CAS 692763-62-5
N-(4-Methoxyphenyl)-2-methyl-N-thiophen-2-ylsulfonylpropanamide
CAS 692763-62-5C15H17NO4S2
N-(4-Chloro-2-methylphenyl)thiophene-2-sulfonamide chemical structure, C11H10ClNO2S2, CAS 403670-27-9
N-(4-Chloro-2-methylphenyl)thiophene-2-sulfonamide
CAS 403670-27-9C11H10ClNO2S2
N-(4-Methylphenyl)thiophene-2-sulfonamide chemical structure, C11H11NO2S2, CAS 39810-48-5
N-(4-Methylphenyl)thiophene-2-sulfonamide
CAS 39810-48-5C11H11NO2S2
N-(4-Hydroxyphenyl)thiophene-2-sulfonamide chemical structure, C10H9NO3S2, CAS 53442-35-6
N-(4-Hydroxyphenyl)thiophene-2-sulfonamide
CAS 53442-35-6C10H9NO3S2
N-(2-Methoxyphenyl)thiophene-2-sulfonamide chemical structure, C11H11NO3S2, CAS 53442-32-3
N-(2-Methoxyphenyl)thiophene-2-sulfonamide
CAS 53442-32-3C11H11NO3S2
N-(3-Methylphenyl)thiophene-2-sulfonamide chemical structure, C11H11NO2S2, CAS 39810-47-4
N-(3-Methylphenyl)thiophene-2-sulfonamide
CAS 39810-47-4C11H11NO2S2
4-[Acetyl(2-thienylsulfonyl)amino]phenyl acetate chemical structure, C14H13NO5S2, CAS 494827-71-3
4-[Acetyl(2-thienylsulfonyl)amino]phenyl acetate
CAS 494827-71-3C14H13NO5S2
2-Hydroxy-5-(thiophene-2-sulfonamido)benzoic acid chemical structure, C11H9NO5S2, CAS 326023-08-9
2-Hydroxy-5-(thiophene-2-sulfonamido)benzoic acid
CAS 326023-08-9C11H9NO5S2
N-(2,4-Dimethylphenyl)-2-thiophenesulfonamide chemical structure, C12H13NO2S2, CAS 358666-63-4
N-(2,4-Dimethylphenyl)-2-thiophenesulfonamide
CAS 358666-63-4C12H13NO2S2
N-(2,5-Dimethylphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO2S2, CAS 332354-72-0
N-(2,5-Dimethylphenyl)thiophene-2-sulfonamide
CAS 332354-72-0C12H13NO2S2
N-(3,5-Dimethylphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO2S2, CAS 6003-54-9
N-(3,5-Dimethylphenyl)thiophene-2-sulfonamide
CAS 6003-54-9C12H13NO2S2
N-(2-Ethylphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO2S2, CAS 53442-40-3
N-(2-Ethylphenyl)thiophene-2-sulfonamide
CAS 53442-40-3C12H13NO2S2
N-(2-Chlorophenyl)thiophene-2-sulfonamide chemical structure, C10H8ClNO2S2, CAS 53442-36-7
N-(2-Chlorophenyl)thiophene-2-sulfonamide
CAS 53442-36-7C10H8ClNO2S2
N-(4-Chlorophenyl)thiophene-2-sulfonamide chemical structure, C10H8ClNO2S2, CAS 39810-52-1
N-(4-Chlorophenyl)thiophene-2-sulfonamide
CAS 39810-52-1C10H8ClNO2S2
N-(3-Methoxyphenyl)thiophene-2-sulfonamide chemical structure, C11H11NO3S2, CAS 39810-49-6
N-(3-Methoxyphenyl)thiophene-2-sulfonamide
CAS 39810-49-6C11H11NO3S2
N-(4-Ethoxyphenyl)thiophene-2-sulfonamide chemical structure, C12H13NO3S2, CAS 358666-72-5
N-(4-Ethoxyphenyl)thiophene-2-sulfonamide
CAS 358666-72-5C12H13NO3S2
Methyl 2-(thiophen-2-ylsulfonylamino)benzoate chemical structure, C12H11NO4S2, CAS 332354-76-4
Methyl 2-(thiophen-2-ylsulfonylamino)benzoate
CAS 332354-76-4C12H11NO4S2