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Murcko scaffold

Ring system with 2 rings and 14 atoms

91 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
91
With full pages
12
Scaffold SMILES

O=C(Nc1ccccc1)c1ccon1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccon1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 91 chemicals

RefChem:381678 chemical structure, C12H9F3N2O2, CAS 523987-35-1
RefChem:381678
CAS 523987-35-1C12H9F3N2O2
N-(4-Acetylphenyl)-5-methylisoxazole-3-carboxamide chemical structure, C13H12N2O3, CAS 438213-62-8
N-(4-Acetylphenyl)-5-methylisoxazole-3-carboxamide
CAS 438213-62-8C13H12N2O3
Methyl 2-(5-methylisoxazole-3-carboxamido)benzoate chemical structure, C13H12N2O4, CAS 717860-15-6
Methyl 2-(5-methylisoxazole-3-carboxamido)benzoate
CAS 717860-15-6C13H12N2O4
N-(2-Bromo-4,6-difluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C11H7BrF2N2O2, CAS 717866-64-3
N-(2-Bromo-4,6-difluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide
CAS 717866-64-3C11H7BrF2N2O2
Diethyl 5-{[(5-methyl-3-isoxazolyl)carbonyl]amino}isophthalate chemical structure, C17H18N2O6, CAS 717869-57-3
Diethyl 5-{[(5-methyl-3-isoxazolyl)carbonyl]amino}isophthalate
CAS 717869-57-3C17H18N2O6
5-Methyl-N-(2-(methylthio)phenyl)isoxazole-3-carboxamide chemical structure, C12H12N2O2S, CAS 717873-80-8
5-Methyl-N-(2-(methylthio)phenyl)isoxazole-3-carboxamide
CAS 717873-80-8C12H12N2O2S
N-(3-Acetylphenyl)-5-methylisoxazole-3-carboxamide chemical structure, C13H12N2O3, CAS 784086-73-3
N-(3-Acetylphenyl)-5-methylisoxazole-3-carboxamide
CAS 784086-73-3C13H12N2O3
3-Isoxazolecarboxamide, 5-methyl-N-phenyl- chemical structure, C11H10N2O2, CAS 99984-65-3
3-Isoxazolecarboxamide, 5-methyl-N-phenyl-
CAS 99984-65-3C11H10N2O2
N-(3-Chlorophenyl)-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C11H9ClN2O2, CAS 646530-35-0
N-(3-Chlorophenyl)-5-methyl-1,2-oxazole-3-carboxamide
CAS 646530-35-0C11H9ClN2O2
N-(4-Fluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C11H9FN2O2, CAS 646530-40-7
N-(4-Fluorophenyl)-5-methyl-1,2-oxazole-3-carboxamide
CAS 646530-40-7C11H9FN2O2
5-Methyl-N-(4-sulfamoylphenyl)isoxazole-3-carboxamide chemical structure, C11H11N3O4S, CAS 92290-49-8
5-Methyl-N-(4-sulfamoylphenyl)isoxazole-3-carboxamide
CAS 92290-49-8C11H11N3O4S
5-Methyl-N-[3-(2,2,3,3-tetrafluoropropoxy)-5-(2,2,2-trifluoroethoxy)phenyl]-1,2-oxazole-3-carboxamide chemical structure, C16H13F7N2O4, CAS 830339-09-8
5-Methyl-N-[3-(2,2,3,3-tetrafluoropropoxy)-5-(2,2,2-trifluoroethoxy)phenyl]-1,2-oxazole-3-carboxamide
CAS 830339-09-8C16H13F7N2O4
N-(2-Methoxy-4-nitrophenyl)-5-methyl-1,2-oxazole-3-carboxamide chemical structure, C12H11N3O5, CAS 717858-22-5
N-(2-Methoxy-4-nitrophenyl)-5-methyl-1,2-oxazole-3-carboxamide
CAS 717858-22-5C12H11N3O5
5-Methyl-N-(2-nitrophenyl)-1,2-oxazole-3-carboxamide chemical structure, C11H9N3O4, CAS 717858-34-9
5-Methyl-N-(2-nitrophenyl)-1,2-oxazole-3-carboxamide
CAS 717858-34-9C11H9N3O4
3-Isoxazolecarboxamide, N-(2-methoxyphenyl)-5-methyl- chemical structure, C12H12N2O3, CAS 88812-95-7
3-Isoxazolecarboxamide, N-(2-methoxyphenyl)-5-methyl-
CAS 88812-95-7C12H12N2O3
3-Isoxazolecarboxamide, 5-methyl-N-(2-methylphenyl)- chemical structure, C12H12N2O2, CAS 108651-13-4
3-Isoxazolecarboxamide, 5-methyl-N-(2-methylphenyl)-
CAS 108651-13-4C12H12N2O2
3-Isoxazolecarboxamide, 5-(((aminocarbonyl)oxy)methyl)-N-(2,6-dimethylphenyl)- chemical structure, C14H15N3O4, CAS 139297-28-2
3-Isoxazolecarboxamide, 5-(((aminocarbonyl)oxy)methyl)-N-(2,6-dimethylphenyl)-
CAS 139297-28-2C14H15N3O4
3-Isoxazolecarboxamide, 5-acetyl-N-(2,6-dimethylphenyl)- chemical structure, C14H14N2O3, CAS 139297-29-3
3-Isoxazolecarboxamide, 5-acetyl-N-(2,6-dimethylphenyl)-
CAS 139297-29-3C14H14N2O3
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(methoxymethyl)- chemical structure, C14H16N2O3, CAS 139297-30-6
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(methoxymethyl)-
CAS 139297-30-6C14H16N2O3
Propanoic acid, 2,2-dimethyl-, (3-(((2,6-dimethylphenyl)amino)carbonyl)-5-isoxazolyl)methyl ester chemical structure, C18H22N2O4, CAS 139297-36-2
Propanoic acid, 2,2-dimethyl-, (3-(((2,6-dimethylphenyl)amino)carbonyl)-5-isoxazolyl)methyl ester
CAS 139297-36-2C18H22N2O4
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(fluoromethyl)- chemical structure, C13H13FN2O2, CAS 139297-39-5
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(fluoromethyl)-
CAS 139297-39-5C13H13FN2O2
3-Isoxazolecarboxamide, 5-(chloromethyl)-N-(2,6-dimethylphenyl)- chemical structure, C13H13ClN2O2, CAS 139297-40-8
3-Isoxazolecarboxamide, 5-(chloromethyl)-N-(2,6-dimethylphenyl)-
CAS 139297-40-8C13H13ClN2O2
3-Isoxazolecarboxamide, 5-methyl-N-(2-(trifluoromethyl)phenyl)- chemical structure, C12H9F3N2O2, CAS 145440-85-3
3-Isoxazolecarboxamide, 5-methyl-N-(2-(trifluoromethyl)phenyl)-
CAS 145440-85-3C12H9F3N2O2
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(1-hydroxyethyl)- chemical structure, C14H16N2O3, CAS 145440-88-6
3-Isoxazolecarboxamide, N-(2,6-dimethylphenyl)-5-(1-hydroxyethyl)-
CAS 145440-88-6C14H16N2O3