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Murcko scaffold

2,3-Dihydro-2-phenyl-1H-isoindol-1-one scaffold

171 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
171
With full pages
32
Scaffold SMILES

O=C1c2ccccc2CN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydro-2-phenyl-1H-isoindol-1-one page
Murcko scaffold O=C1c2ccccc2CN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 171 chemicals

Indoprofen chemical structure, C17H15NO3, CAS 31842-01-0
Indoprofen
CAS 31842-01-0C17H15NO3
Indobufen, (S)- chemical structure, C18H17NO3, CAS 118289-97-7
Indobufen, (S)-
CAS 118289-97-7C18H17NO3
(R*,S*)-(1)-2,3-Dihydro-3-(2-hydroxy-3-(isopropylamino)propoxy)-2-phenyl-1H-isoindol-1-one fumarate chemical structure, C24H30N2O7, CAS 70096-14-9
(R*,S*)-(1)-2,3-Dihydro-3-(2-hydroxy-3-(isopropylamino)propoxy)-2-phenyl-1H-isoindol-1-one fumarate
CAS 70096-14-9C24H30N2O7
Nofecainide chemical structure, C20H24N2O3, CAS 50516-43-3
Nofecainide
CAS 50516-43-3C20H24N2O3
(S)-Indoprofen chemical structure, C17H15NO3, CAS 53086-13-8
(S)-Indoprofen
CAS 53086-13-8C17H15NO3
2,3-Dihydro-3-hydroxy-2-phenyl-1H-isoindol-1-one chemical structure, C14H11NO2, CAS 18167-15-2
2,3-Dihydro-3-hydroxy-2-phenyl-1H-isoindol-1-one
CAS 18167-15-2C14H11NO2
(-)-Indoprofen chemical structure, C17H15NO3, CAS 53086-14-9
(-)-Indoprofen
CAS 53086-14-9C17H15NO3
2,3-Dihydro-2-phenyl-1H-isoindol-1-one chemical structure, C14H11NO, CAS 5388-42-1
2,3-Dihydro-2-phenyl-1H-isoindol-1-one
CAS 5388-42-1C14H11NO
Indobufen chemical structure, C18H17NO3, CAS 63610-08-2
Indobufen
CAS 63610-08-2C18H17NO3
2-Oxo-3-(4-(1-oxo-2-isoindolinyl)phenyl)butanamide chemical structure, C18H16N2O3, CAS 67358-82-1
2-Oxo-3-(4-(1-oxo-2-isoindolinyl)phenyl)butanamide
CAS 67358-82-1C18H16N2O3
Nofedone chemical structure, C20H24N2O3, CAS 70096-13-8
Nofedone
CAS 70096-13-8C20H24N2O3
(R)-Indobufen chemical structure, C18H17NO3, CAS 131484-83-8
(R)-Indobufen
CAS 131484-83-8C18H17NO3
2-Hydroxy-3-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanamide chemical structure, C18H18N2O3, CAS 84244-54-2
2-Hydroxy-3-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanamide
CAS 84244-54-2C18H18N2O3
2-(4-Nitrophenyl)-2,3-dihydro-1H-isoindol-1-one chemical structure, C14H10N2O3, CAS 4770-74-5
2-(4-Nitrophenyl)-2,3-dihydro-1H-isoindol-1-one
CAS 4770-74-5C14H10N2O3
1H-Isoindole-1-acetic acid, 2,3-dihydro-3-oxo-2-phenyl-, ethyl ester chemical structure, C18H17NO3, CAS 88460-50-8
1H-Isoindole-1-acetic acid, 2,3-dihydro-3-oxo-2-phenyl-, ethyl ester
CAS 88460-50-8C18H17NO3
1H-Isoindol-1-one, 2,3-dihydro-2-(4-hydroxyphenyl)- chemical structure, C14H11NO2, CAS 4778-80-7
1H-Isoindol-1-one, 2,3-dihydro-2-(4-hydroxyphenyl)-
CAS 4778-80-7C14H11NO2
1H-Isoindole-4-carboxylic acid, 2,3-dihydro-3-oxo-2-phenyl-, ethyl ester chemical structure, C17H15NO3, CAS 831203-51-1
1H-Isoindole-4-carboxylic acid, 2,3-dihydro-3-oxo-2-phenyl-, ethyl ester
CAS 831203-51-1C17H15NO3
2-(4-Fluorophenyl)-1-isoindolinone chemical structure, C14H10FNO, CAS 75318-28-4
2-(4-Fluorophenyl)-1-isoindolinone
CAS 75318-28-4C14H10FNO
Methyl 2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoate chemical structure, C18H17NO3, CAS 50712-44-2
Methyl 2-(4-(1-oxoisoindolin-2-yl)phenyl)propanoate
CAS 50712-44-2C18H17NO3
6,7-Dimethoxy-2-[3-(trifluoromethyl)phenyl]-3H-isoindol-1-one chemical structure, C17H14F3NO3, CAS 339287-24-0
6,7-Dimethoxy-2-[3-(trifluoromethyl)phenyl]-3H-isoindol-1-one
CAS 339287-24-0C17H14F3NO3
N-[3-(4,5-Dimethoxy-3-oxo-1H-isoindol-2-yl)phenyl]acetamide chemical structure, C18H18N2O4, CAS 329722-15-8
N-[3-(4,5-Dimethoxy-3-oxo-1H-isoindol-2-yl)phenyl]acetamide
CAS 329722-15-8C18H18N2O4
2-(3-Fluorophenyl)-6,7-dimethoxy-1-isoindolinone chemical structure, C16H14FNO3, CAS 5975-68-8
2-(3-Fluorophenyl)-6,7-dimethoxy-1-isoindolinone
CAS 5975-68-8C16H14FNO3
2-(4-Chlorophenyl)-6,7-dimethoxyisoindolin-1-one chemical structure, C16H14ClNO3, CAS 499183-68-5
2-(4-Chlorophenyl)-6,7-dimethoxyisoindolin-1-one
CAS 499183-68-5C16H14ClNO3
2-(4-Fluorophenyl)-6,7-dimethoxyisoindolin-1-one chemical structure, C16H14FNO3, CAS 499183-67-4
2-(4-Fluorophenyl)-6,7-dimethoxyisoindolin-1-one
CAS 499183-67-4C16H14FNO3