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Murcko scaffold

Ring system with 2 rings and 18 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(CC1C=NNC1=O)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1C=NNC1=O)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-[(2,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C13H12Cl2N4O2, CAS 5988-96-5
N-[(2,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 5988-96-5C13H12Cl2N4O2
N-[(E)-(3,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C13H12Cl2N4O2, CAS 306952-68-1
N-[(E)-(3,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 306952-68-1C13H12Cl2N4O2
N-[(E)-(2-Chlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C13H13ClN4O2, CAS 306952-85-2
N-[(E)-(2-Chlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 306952-85-2C13H13ClN4O2
2-(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)-N'-[1-(3-nitrophenyl)ethylidene]acetohydrazide chemical structure, C14H15N5O4, CAS 5893-15-2
2-(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)-N'-[1-(3-nitrophenyl)ethylidene]acetohydrazide
CAS 5893-15-2C14H15N5O4
N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C13H12Cl2N4O2, CAS 306952-57-8
N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 306952-57-8C13H12Cl2N4O2
N'-[(E)-(3-Hydroxyphenyl)methylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide chemical structure, C13H14N4O3, CAS 5901-28-0
N'-[(E)-(3-Hydroxyphenyl)methylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide
CAS 5901-28-0C13H14N4O3
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C14H16N4O3, CAS 306952-79-4
N-[(E)-(4-Methoxyphenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 306952-79-4C14H16N4O3
2-(3-Methyl-5-oxo-1,4-dihydropyrazol-4-yl)-N-[(E)-(3-nitrophenyl)methylideneamino]acetamide chemical structure, C13H13N5O4, CAS 307346-96-9
2-(3-Methyl-5-oxo-1,4-dihydropyrazol-4-yl)-N-[(E)-(3-nitrophenyl)methylideneamino]acetamide
CAS 307346-96-9C13H13N5O4
Methyl 4-[(E)-[[2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetyl]hydrazinylidene]methyl]benzoate chemical structure, C15H16N4O4, CAS 307346-91-4
Methyl 4-[(E)-[[2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetyl]hydrazinylidene]methyl]benzoate
CAS 307346-91-4C15H16N4O4
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide chemical structure, C13H12Cl2N4O2, CAS 306952-89-6
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide
CAS 306952-89-6C13H12Cl2N4O2
N'-{(E)-[4-(diethylamino)phenyl]methylidene}-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide chemical structure, C17H23N5O2, CAS 306952-91-0
N'-{(E)-[4-(diethylamino)phenyl]methylidene}-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide
CAS 306952-91-0C17H23N5O2
N'-[(E)-(2-Chloro-6-fluorophenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide chemical structure, C13H12ClFN4O2, CAS 306952-56-7
N'-[(E)-(2-Chloro-6-fluorophenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide
CAS 306952-56-7C13H12ClFN4O2
N'-[(E)-(5-Bromo-2-methoxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide chemical structure, C14H15BrN4O3, CAS 306952-54-5
N'-[(E)-(5-Bromo-2-methoxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide
CAS 306952-54-5C14H15BrN4O3
2-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)-N'-[(E)-(2,3,4-trimethoxyphenyl)methylidene]acetohydrazide chemical structure, C16H20N4O5, CAS 306952-70-5
2-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)-N'-[(E)-(2,3,4-trimethoxyphenyl)methylidene]acetohydrazide
CAS 306952-70-5C16H20N4O5
N'-[(E)-(3-Bromophenyl)methylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide chemical structure, C13H13BrN4O2, CAS 306952-43-2
N'-[(E)-(3-Bromophenyl)methylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide
CAS 306952-43-2C13H13BrN4O2
N'-[4-(Diethylamino)-2-hydroxybenzylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide chemical structure, C17H23N5O3, CAS 306952-75-0
N'-[4-(Diethylamino)-2-hydroxybenzylidene]-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide
CAS 306952-75-0C17H23N5O3
(E)-N'-(4-Hydroxy-3-methoxybenzylidene)-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide chemical structure, C14H16N4O4, CAS 306952-83-0
(E)-N'-(4-Hydroxy-3-methoxybenzylidene)-2-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)acetohydrazide
CAS 306952-83-0C14H16N4O4
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide chemical structure, C14H16N4O4, CAS 306952-47-6
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide
CAS 306952-47-6C14H16N4O4
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide chemical structure, C13H14N4O4, CAS 306952-81-8
N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide
CAS 306952-81-8C13H14N4O4
N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide chemical structure, C13H13BrN4O3, CAS 306952-64-7
N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-2-(3-hydroxy-5-methyl-4H-pyrazol-4-yl)acetohydrazide
CAS 306952-64-7C13H13BrN4O3
2-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)-N'-[(E)-(2-hydroxyphenyl)methylidene]acetohydrazide chemical structure, C13H14N4O3, CAS 306952-80-7
2-(3-Hydroxy-5-methyl-4H-pyrazol-4-yl)-N'-[(E)-(2-hydroxyphenyl)methylidene]acetohydrazide
CAS 306952-80-7C13H14N4O3