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Murcko scaffold

Ring system with 2 rings and 8 atoms

68 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 8
Chemicals: 68
With full pages: 15

Scaffold SMILES

c1cc2cn[nH]c2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1cc2cn[nH]c2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 68 chemicals

N-[1-Methyl-3-(trifluoromethyl)-5-thieno[2,3-c]pyrazolyl]carbamic acid 2,2-dimethylpropyl ester chemical structure, C13H16F3N3O2S, CAS 866143-90-0

N-[1-Methyl-3-(trifluoromethyl)-5-thieno[2,3-c]pyrazolyl]carbamic acid 2,2-dimethylpropyl ester

CAS 866143-90-0C₁₃H₁₆F₃N₃O₂S

5-(Bromomethyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole chemical structure, C8H6BrF3N2S, CAS 338982-24-4

5-(Bromomethyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole

CAS 338982-24-4C₈H₆BrF₃N₂S

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid chemical structure, C8H5F3N2O2S, CAS 338982-15-3

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid

CAS 338982-15-3C₈H₅F₃N₂O₂S

[1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl]methanol chemical structure, C8H7F3N2OS, CAS 338982-22-2

[1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl]methanol

CAS 338982-22-2C₈H₇F₃N₂OS

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid chemical structure, C8H8N2O2S, CAS 25252-46-4

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid

CAS 25252-46-4C₈H₈N₂O₂S

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbonyl chloride chemical structure, C8H7ClN2OS, CAS 388088-75-3

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbonyl chloride

CAS 388088-75-3C₈H₇ClN₂OS

(1,3-Dimethyl-1H-thieno[2,3-c]pyrazol-5-yl)methanol chemical structure, C8H10N2OS, CAS 423769-75-9

(1,3-Dimethyl-1H-thieno[2,3-c]pyrazol-5-yl)methanol

CAS 423769-75-9C₈H₁₀N₂OS

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbaldehyde chemical structure, C8H5F3N2OS, CAS 886360-61-8

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbaldehyde

CAS 886360-61-8C₈H₅F₃N₂OS

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide chemical structure, C8H7F3N4OS, CAS 886360-63-0

1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carbohydrazide

CAS 886360-63-0C₈H₇F₃N₄OS

Methyl 1,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylate chemical structure, C9H10N2O2S, CAS 675819-58-6

Methyl 1,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylate

CAS 675819-58-6C₉H₁₀N₂O₂S

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide chemical structure, C8H10N4OS, CAS 676997-68-5

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbohydrazide

CAS 676997-68-5C₈H₁₀N₄OS

Methyl 1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylate chemical structure, C9H7F3N2O2S, CAS 677704-91-5

Methyl 1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylate

CAS 677704-91-5C₉H₇F₃N₂O₂S

Ethyl 1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylate chemical structure, C10H9F3N2O2S, CAS 320422-49-9

Ethyl 1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylate

CAS 320422-49-9C₁₀H₉F₃N₂O₂S

N-Allyl-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide chemical structure, C11H10F3N3OS, CAS 477886-37-6

N-Allyl-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide

CAS 477886-37-6C₁₁H₁₀F₃N₃OS

1-Methyl-N-propyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide chemical structure, C11H12F3N3OS, CAS 477886-38-7

1-Methyl-N-propyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide

CAS 477886-38-7C₁₁H₁₂F₃N₃OS

N-Isopropyl-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide chemical structure, C11H12F3N3OS, CAS 477886-39-8

N-Isopropyl-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide

CAS 477886-39-8C₁₁H₁₂F₃N₃OS

N-Ethyl-2-{[1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl]carbonyl}-1-hydrazinecarbothioamide chemical structure, C11H12F3N5OS2, CAS 865659-80-9

N-Ethyl-2-{[1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl]carbonyl}-1-hydrazinecarbothioamide

CAS 865659-80-9C₁₁H₁₂F₃N₅OS₂

3-Methyl-1-(2-methylpropyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid chemical structure, C11H14N2O2S, CAS 855715-27-4

3-Methyl-1-(2-methylpropyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid

CAS 855715-27-4C₁₁H₁₄N₂O₂S

tert-Butyl 3-amino-1H-thieno[2,3-c]pyrazole-5-carboxylate chemical structure, C10H13N3O2S, CAS 656235-18-6

tert-Butyl 3-amino-1H-thieno[2,3-c]pyrazole-5-carboxylate

CAS 656235-18-6C₁₀H₁₃N₃O₂S

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbaldehyde chemical structure, C8H8N2OS, CAS 50880-19-8

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carbaldehyde

CAS 50880-19-8C₈H₈N₂OS

1-Methyl-3-(propan-2-yl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid chemical structure, C10H12N2O2S, CAS 1094271-45-0

1-Methyl-3-(propan-2-yl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid

CAS 1094271-45-0C₁₀H₁₂N₂O₂S

3-Ethyl-1-methyl-1H-thieno[2,3-C]pyrazole-5-carboxylic acid chemical structure, C9H10N2O2S, CAS 1094434-29-3

3-Ethyl-1-methyl-1H-thieno[2,3-C]pyrazole-5-carboxylic acid

CAS 1094434-29-3C₉H₁₀N₂O₂S

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxamide chemical structure, C8H9N3OS, CAS 1098360-43-0

1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxamide

CAS 1098360-43-0C₈H₉N₃OS

2-({1,3-Dimethyl-1H-thieno[2,3-c]pyrazol-5-yl}formamido)propanoic acid chemical structure, C11H13N3O3S, CAS 1309001-73-7

2-({1,3-Dimethyl-1H-thieno[2,3-c]pyrazol-5-yl}formamido)propanoic acid

CAS 1309001-73-7C₁₁H₁₃N₃O₃S