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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
7
Scaffold SMILES

O=C1NC(=Nc2ccccc2)SC1=Cc1ccc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=Nc2ccccc2)SC1=Cc1ccc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(2E,5Z)-2-[(3-Methylphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one chemical structure, C16H15N3OS, CAS 591209-89-1
(2E,5Z)-2-[(3-Methylphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one
CAS 591209-89-1C16H15N3OS
(2E,5Z)-2-((3,4-Dimethylphenyl)imino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazolidin-4-one chemical structure, C17H17N3OS, CAS 844663-49-6
(2E,5Z)-2-((3,4-Dimethylphenyl)imino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazolidin-4-one
CAS 844663-49-6C17H17N3OS
(2E,5Z)-5-((1-Methyl-1H-pyrrol-2-yl)methylene)-2-(p-tolylimino)thiazolidin-4-one chemical structure, C16H15N3OS, CAS 444560-66-1
(2E,5Z)-5-((1-Methyl-1H-pyrrol-2-yl)methylene)-2-(p-tolylimino)thiazolidin-4-one
CAS 444560-66-1C16H15N3OS
(Z)-2-((4-Chloro-2-(trifluoromethyl)phenyl)amino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazol-4(5H)-one chemical structure, C16H11ClF3N3OS, CAS 848989-67-3
(Z)-2-((4-Chloro-2-(trifluoromethyl)phenyl)amino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazol-4(5H)-one
CAS 848989-67-3C16H11ClF3N3OS
4(5H)-Thiazolone,2-[(2-methylphenyl)amino]-5-[(1-methyl-1H-pyrrol-2-yl)methylene]-(9CI) chemical structure, C16H15N3OS, CAS 591209-92-6
4(5H)-Thiazolone,2-[(2-methylphenyl)amino]-5-[(1-methyl-1H-pyrrol-2-yl)methylene]-(9CI)
CAS 591209-92-6C16H15N3OS
(2E,5Z)-2-[(2,3-Dimethylphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one chemical structure, C17H17N3OS, CAS 847048-70-8
(2E,5Z)-2-[(2,3-Dimethylphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one
CAS 847048-70-8C17H17N3OS
(2E,5Z)-2-[(4-Hydroxyphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one chemical structure, C15H13N3O2S, CAS 716340-80-6
(2E,5Z)-2-[(4-Hydroxyphenyl)imino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazolidin-4-one
CAS 716340-80-6C15H13N3O2S
(2E,5Z)-2-((2,4-Dimethylphenyl)imino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazolidin-4-one chemical structure, C17H17N3OS, CAS 844456-70-8
(2E,5Z)-2-((2,4-Dimethylphenyl)imino)-5-((1-methyl-1H-pyrrol-2-yl)methylene)thiazolidin-4-one
CAS 844456-70-8C17H17N3OS
(5Z)-2-[(3-Hydroxyphenyl)amino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazol-4(5H)-one chemical structure, C15H13N3O2S, CAS 848754-83-6
(5Z)-2-[(3-Hydroxyphenyl)amino]-5-[(1-methyl-1H-pyrrol-2-yl)methylidene]-1,3-thiazol-4(5H)-one
CAS 848754-83-6C15H13N3O2S