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Murcko scaffold

4-(1H-Pyrazol-3-yl)pyrimidine scaffold

100 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
100
With full pages
3
Scaffold SMILES

c1cc(-c2cc[nH]n2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1H-Pyrazol-3-yl)pyrimidine page
Murcko scaffold c1cc(-c2cc[nH]n2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 100 chemicals

2-Hydrazinyl-4-(1-methyl-1H-pyrazol-3-yl)pyrimidine chemical structure, C8H10N6, CAS 1006322-90-2
2-Hydrazinyl-4-(1-methyl-1H-pyrazol-3-yl)pyrimidine
CAS 1006322-90-2C8H10N6
Ethyl 2-((4-(1-methyl-1H-pyrazol-3-yl)pyrimidin-2-yl)thio)acetate chemical structure, C12H14N4O2S, CAS 1006323-19-8
Ethyl 2-((4-(1-methyl-1H-pyrazol-3-yl)pyrimidin-2-yl)thio)acetate
CAS 1006323-19-8C12H14N4O2S
2-((4-(1-Methyl-1H-pyrazol-5-yl)pyrimidin-2-yl)thio)acetic acid chemical structure, C10H10N4O2S, CAS 1006320-18-8
2-((4-(1-Methyl-1H-pyrazol-5-yl)pyrimidin-2-yl)thio)acetic acid
CAS 1006320-18-8C10H10N4O2S
2-[[4-(1-Methyl-1H-pyrazol-5-yl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]acetic acid chemical structure, C11H9F3N4O2S, CAS 1006486-87-8
2-[[4-(1-Methyl-1H-pyrazol-5-yl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]acetic acid
CAS 1006486-87-8C11H9F3N4O2S
2-Methylsulfanyl-4-(1H-pyrazol-5-yl)pyrimidine chemical structure, C8H8N4S, CAS 496863-64-0
2-Methylsulfanyl-4-(1H-pyrazol-5-yl)pyrimidine
CAS 496863-64-0C8H8N4S
2-Chloro-5-methyl-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine chemical structure, C9H9ClN4, CAS 1202986-04-6
2-Chloro-5-methyl-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine
CAS 1202986-04-6C9H9ClN4
4-(1H-Pyrazol-3-yl)pyrimidine chemical structure, C7H6N4, CAS 1190280-83-1
4-(1H-Pyrazol-3-yl)pyrimidine
CAS 1190280-83-1C7H6N4
6-(1H-Pyrazol-3-yl)-4-pyrimidinecarboxylic acid chemical structure, C8H6N4O2, CAS 1097254-65-3
6-(1H-Pyrazol-3-yl)-4-pyrimidinecarboxylic acid
CAS 1097254-65-3C8H6N4O2
Methyl 5-amino-3-pyrimidin-4-ylpyrazole-1-carboxylate chemical structure, C9H9N5O2, CAS 1232225-30-7
Methyl 5-amino-3-pyrimidin-4-ylpyrazole-1-carboxylate
CAS 1232225-30-7C9H9N5O2
4-Chloro-6-(1-methyl-1H-pyrazol-5-yl)pyrimidine chemical structure, C8H7ClN4, CAS 1482088-70-9
4-Chloro-6-(1-methyl-1H-pyrazol-5-yl)pyrimidine
CAS 1482088-70-9C8H7ClN4
3-(2-Methylsulfanylpyrimidin-4-yl)-1H-pyrazole-5-carboxamide chemical structure, C9H9N5OS, CAS 1403332-45-5
3-(2-Methylsulfanylpyrimidin-4-yl)-1H-pyrazole-5-carboxamide
CAS 1403332-45-5C9H9N5OS
1-tert-Butyl-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxamide chemical structure, C13H17N5OS, CAS 1403332-50-2
1-tert-Butyl-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxamide
CAS 1403332-50-2C13H17N5OS
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]pyrazole-3-carboxamide chemical structure, C14H20N6O, CAS 1403332-57-9
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]pyrazole-3-carboxamide
CAS 1403332-57-9C14H20N6O
1-tert-Butyl-5-(2-methoxypyrimidin-4-yl)pyrazole-3-carboxamide chemical structure, C13H17N5O2, CAS 1403332-55-7
1-tert-Butyl-5-(2-methoxypyrimidin-4-yl)pyrazole-3-carboxamide
CAS 1403332-55-7C13H17N5O2
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]-N-methylpyrazole-3-carboxamide chemical structure, C15H22N6O, CAS 1403332-75-1
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]-N-methylpyrazole-3-carboxamide
CAS 1403332-75-1C15H22N6O
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]-N-propan-2-ylpyrazole-3-carboxamide chemical structure, C17H26N6O, CAS 1403332-77-3
1-tert-Butyl-5-[2-(dimethylamino)pyrimidin-4-yl]-N-propan-2-ylpyrazole-3-carboxamide
CAS 1403332-77-3C17H26N6O
4-(5-Amino-1-methyl-1H-pyrazol-3-yl)-N-methylpyrimidin-2-amine chemical structure, C9H12N6, CAS 1240521-65-6
4-(5-Amino-1-methyl-1H-pyrazol-3-yl)-N-methylpyrimidin-2-amine
CAS 1240521-65-6C9H12N6
4-(4-Bromo-1H-pyrazol-3-yl)-2-trifluoromethyl-pyrimidine chemical structure, C8H4BrF3N4, CAS 878760-57-7
4-(4-Bromo-1H-pyrazol-3-yl)-2-trifluoromethyl-pyrimidine
CAS 878760-57-7C8H4BrF3N4
4-Bromo-3-(2-trifluoromethyl-pyrimidin-4-yl)-pyrazole-1-sulfonic acid dimethylamide chemical structure, C10H9BrF3N5O2S, CAS 878760-58-8
4-Bromo-3-(2-trifluoromethyl-pyrimidin-4-yl)-pyrazole-1-sulfonic acid dimethylamide
CAS 878760-58-8C10H9BrF3N5O2S
4-(1H-Pyrazol-3-yl)-2-trifluoromethyl-pyrimidine chemical structure, C8H5F3N4, CAS 878760-56-6
4-(1H-Pyrazol-3-yl)-2-trifluoromethyl-pyrimidine
CAS 878760-56-6C8H5F3N4
Ethyl 1-tert-butyl-5-[2-(methylsulfonyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxylate chemical structure, C15H20N4O4S, CAS 1403333-68-5
Ethyl 1-tert-butyl-5-[2-(methylsulfonyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxylate
CAS 1403333-68-5C15H20N4O4S
Ethyl 3-(2-methylsulfanylpyrimidin-4-yl)-1H-pyrazole-5-carboxylate chemical structure, C11H12N4O2S, CAS 1403333-55-0
Ethyl 3-(2-methylsulfanylpyrimidin-4-yl)-1H-pyrazole-5-carboxylate
CAS 1403333-55-0C11H12N4O2S
3-(2-Methoxypyrimidin-4-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C9H8N4O3, CAS 1403333-90-3
3-(2-Methoxypyrimidin-4-yl)-1H-pyrazole-5-carboxylic acid
CAS 1403333-90-3C9H8N4O3
Ethyl 1-tert-butyl-5-(2-methylsulfanylpyrimidin-4-yl)pyrazole-3-carboxylate chemical structure, C15H20N4O2S, CAS 1403333-56-1
Ethyl 1-tert-butyl-5-(2-methylsulfanylpyrimidin-4-yl)pyrazole-3-carboxylate
CAS 1403333-56-1C15H20N4O2S