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Murcko scaffold

5,6,7,8-Tetrahydro-1,6-naphthyridine scaffold

360 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
360
With full pages
23
Scaffold SMILES

c1cnc2c(c1)CNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5,6,7,8-Tetrahydro-1,6-naphthyridine page
Murcko scaffold c1cnc2c(c1)CNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 360 chemicals

N2,N2,6-Trimethyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2,4-diamine chemical structure, C11H18N4, CAS 351068-22-9
N2,N2,6-Trimethyl-5,6,7,8-tetrahydro-1,6-naphthyridine-2,4-diamine
CAS 351068-22-9C11H18N4
2-[(3-Cyano-6-methyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)sulfanyl]acetamide chemical structure, C12H14N4OS, CAS 340817-39-2
2-[(3-Cyano-6-methyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)sulfanyl]acetamide
CAS 340817-39-2C12H14N4OS
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-pentyl- chemical structure, C13H20N2, CAS 75509-68-1
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-pentyl-
CAS 75509-68-1C13H20N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(2-propenyl)- chemical structure, C11H14N2, CAS 75509-69-2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(2-propenyl)-
CAS 75509-69-2C11H14N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3-butenyl)- chemical structure, C12H16N2, CAS 75509-70-5
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3-butenyl)-
CAS 75509-70-5C12H16N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-hexyl- chemical structure, C14H22N2, CAS 75509-75-0
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-hexyl-
CAS 75509-75-0C14H22N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-heptyl- chemical structure, C15H24N2, CAS 75509-76-1
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-heptyl-
CAS 75509-76-1C15H24N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3-methylbutyl)- chemical structure, C13H20N2, CAS 75509-77-2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3-methylbutyl)-
CAS 75509-77-2C13H20N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-decyl- chemical structure, C18H30N2, CAS 75509-85-2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-decyl-
CAS 75509-85-2C18H30N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(2-octenyl)- chemical structure, C16H24N2, CAS 75509-78-3
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(2-octenyl)-
CAS 75509-78-3C16H24N2
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3,7-dimethyl-2,6-octadienyl)-, (E)- chemical structure, C18H26N2, CAS 75509-86-3
1,6-Naphthyridine, 5,6,7,8-tetrahydro-6-(3,7-dimethyl-2,6-octadienyl)-, (E)-
CAS 75509-86-3C18H26N2
tert-Butyl 3-nitro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate chemical structure, C13H17N3O4, CAS 355818-98-3
tert-Butyl 3-nitro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
CAS 355818-98-3C13H17N3O4
3-Amino-5,6,7,8-tetrahydro-6,8,8-trimethyl[1,6]naphthyridine chemical structure, C11H17N3, CAS 252901-48-7
3-Amino-5,6,7,8-tetrahydro-6,8,8-trimethyl[1,6]naphthyridine
CAS 252901-48-7C11H17N3
6-(1,1-Dimethylethyl) 7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxylate chemical structure, C14H18N2O4, CAS 259809-49-9
6-(1,1-Dimethylethyl) 7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxylate
CAS 259809-49-9C14H18N2O4
6-tert-Butyl 2-methyl 7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxylate chemical structure, C15H20N2O4, CAS 259809-47-7
6-tert-Butyl 2-methyl 7,8-dihydro-1,6-naphthyridine-2,6(5H)-dicarboxylate
CAS 259809-47-7C15H20N2O4
7,8-Dihydro-1,6-naphthyridine-6(5H)-carboxylic acid 1,1-dimethylethyl ester, 1-oxide chemical structure, C13H18N2O3, CAS 259809-45-5
7,8-Dihydro-1,6-naphthyridine-6(5H)-carboxylic acid 1,1-dimethylethyl ester, 1-oxide
CAS 259809-45-5C13H18N2O3
5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,6-naphthyridine chemical structure, C9H9F3N2, CAS 624734-27-6
5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,6-naphthyridine
CAS 624734-27-6C9H9F3N2
tert-Butyl 7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate chemical structure, C13H18N2O2, CAS 259809-44-4
tert-Butyl 7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
CAS 259809-44-4C13H18N2O2
tert-Butyl 2-cyano-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate chemical structure, C14H17N3O2, CAS 259809-46-6
tert-Butyl 2-cyano-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
CAS 259809-46-6C14H17N3O2
3-Amino-5,6,7,8-tetrahydro-6-methyl-1,6-naphthyridine chemical structure, C9H13N3, CAS 216966-37-9
3-Amino-5,6,7,8-tetrahydro-6-methyl-1,6-naphthyridine
CAS 216966-37-9C9H13N3
tert-Butyl 3-amino-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate chemical structure, C13H19N3O2, CAS 355819-02-2
tert-Butyl 3-amino-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate
CAS 355819-02-2C13H19N3O2
N,3-Dimethyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carbothioamide chemical structure, C11H15N3S, CAS 62230-54-0
N,3-Dimethyl-7,8-dihydro-1,6-naphthyridine-6(5H)-carbothioamide
CAS 62230-54-0C11H15N3S
3-Methyl-5,6,7,8-tetrahydro-1,6-naphthyridine chemical structure, C9H12N2, CAS 83100-02-1
3-Methyl-5,6,7,8-tetrahydro-1,6-naphthyridine
CAS 83100-02-1C9H12N2
6-Ethyl-5,6,7,8-tetrahydro-1,6-naphthyridine chemical structure, C10H14N2, CAS 75509-82-9
6-Ethyl-5,6,7,8-tetrahydro-1,6-naphthyridine
CAS 75509-82-9C10H14N2