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Murcko scaffold

2-Pyridinyl-1,3-dioxolane scaffold

67 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
67
With full pages
7
Scaffold SMILES

c1ccc(C2OCCO2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Pyridinyl-1,3-dioxolane page
Murcko scaffold c1ccc(C2OCCO2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 67 chemicals

2-Pyridinyl-1,3-dioxolane chemical structure, C8H9NO2, CAS 5693-54-9
2-Pyridinyl-1,3-dioxolane
CAS 5693-54-9C8H9NO2
2-Bromo-6-(1,3-dioxolan-2-yl)pyridine chemical structure, C8H8BrNO2, CAS 34199-87-6
2-Bromo-6-(1,3-dioxolan-2-yl)pyridine
CAS 34199-87-6C8H8BrNO2
2-(2-Methyl-1,3-dioxolan-2-yl)pyridine chemical structure, C9H11NO2, CAS 49669-15-0
2-(2-Methyl-1,3-dioxolan-2-yl)pyridine
CAS 49669-15-0C9H11NO2
2-(1,3-Dioxolan-2-yl)-3-nitropyridine chemical structure, C8H8N2O4, CAS 143621-31-2
2-(1,3-Dioxolan-2-yl)-3-nitropyridine
CAS 143621-31-2C8H8N2O4
2-(1,3-Dioxolanyl)-3-aminopyridine chemical structure, C8H10N2O2, CAS 143621-33-4
2-(1,3-Dioxolanyl)-3-aminopyridine
CAS 143621-33-4C8H10N2O2
2-(1,3,-Dioxolan-2-yl)-6-methylpyridine chemical structure, C9H11NO2, CAS 92765-75-8
2-(1,3,-Dioxolan-2-yl)-6-methylpyridine
CAS 92765-75-8C9H11NO2
Acetamide, N-[6-(1,3-dioxolan-2-yl)-4-methyl-3-pyridinyl]- chemical structure, C11H14N2O3, CAS 143621-41-4
Acetamide, N-[6-(1,3-dioxolan-2-yl)-4-methyl-3-pyridinyl]-
CAS 143621-41-4C11H14N2O3
Pyridine, 2-(1,3-dioxolan-2-yl)-4-methyl-3-nitro- chemical structure, C9H10N2O4, CAS 143509-44-8
Pyridine, 2-(1,3-dioxolan-2-yl)-4-methyl-3-nitro-
CAS 143509-44-8C9H10N2O4
3-Pyridinamine, 6-(1,3-dioxolan-2-yl)-4-methyl- chemical structure, C9H12N2O2, CAS 143509-46-0
3-Pyridinamine, 6-(1,3-dioxolan-2-yl)-4-methyl-
CAS 143509-46-0C9H12N2O2
1-(6-[1,3]Dioxolan-2-yl-pyridin-2-yl)ethanone chemical structure, C10H11NO3, CAS 208111-12-0
1-(6-[1,3]Dioxolan-2-yl-pyridin-2-yl)ethanone
CAS 208111-12-0C10H11NO3
2-(1,3-Dioxolan-2-yl)-6-fluoropyridine chemical structure, C8H8FNO2, CAS 208111-44-8
2-(1,3-Dioxolan-2-yl)-6-fluoropyridine
CAS 208111-44-8C8H8FNO2
2-(1,3-Dioxolan-2-yl)-6-cyanopyridine chemical structure, C9H8N2O2, CAS 208111-02-8
2-(1,3-Dioxolan-2-yl)-6-cyanopyridine
CAS 208111-02-8C9H8N2O2
2-Chloro-6-(1,3-dioxolan-2-yl)-3-methylpyridine chemical structure, C9H10ClNO2, CAS 223633-36-1
2-Chloro-6-(1,3-dioxolan-2-yl)-3-methylpyridine
CAS 223633-36-1C9H10ClNO2
2-(2-Ethyl-1,3-dioxolan-2-yl)-6-methylpyridine chemical structure, C11H15NO2, CAS 165126-72-7
2-(2-Ethyl-1,3-dioxolan-2-yl)-6-methylpyridine
CAS 165126-72-7C11H15NO2
2-(2-Methyl-1,3-dioxolan-2-yl)-6-(tributylstannyl)pyridine chemical structure, C21H37NO2Sn, CAS 874379-32-5
2-(2-Methyl-1,3-dioxolan-2-yl)-6-(tributylstannyl)pyridine
CAS 874379-32-5C21H37NO2Sn
(Dioxolan-2-yl)-1-methyl-pyridinium iodide chemical structure, C9H12INO2, CAS 112390-98-4
(Dioxolan-2-yl)-1-methyl-pyridinium iodide
CAS 112390-98-4C9H12INO2
2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine chemical structure, C9H10BrNO2, CAS 49669-14-9
2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine
CAS 49669-14-9C9H10BrNO2
4-Chloro-2-(1,3-dioxolan-2-yl)pyridine chemical structure, C8H8ClNO2, CAS 59886-79-2
4-Chloro-2-(1,3-dioxolan-2-yl)pyridine
CAS 59886-79-2C8H8ClNO2
4-Chloro-2-(1,3-dioxolan-2-yl)-3-methylpyridine chemical structure, C9H10ClNO2, CAS 59886-87-2
4-Chloro-2-(1,3-dioxolan-2-yl)-3-methylpyridine
CAS 59886-87-2C9H10ClNO2
Pyridine, 2-(1,3-dioxolan-2-yl)-4-methyl-5-nitro- chemical structure, C9H10N2O4, CAS 119694-70-1
Pyridine, 2-(1,3-dioxolan-2-yl)-4-methyl-5-nitro-
CAS 119694-70-1C9H10N2O4
4-Pyridinepropanoic acid,2-(1,3-dioxolan-2-yl)-5-nitro-a-oxo-,ethyl ester chemical structure, C13H14N2O7, CAS 119694-71-2
4-Pyridinepropanoic acid,2-(1,3-dioxolan-2-yl)-5-nitro-a-oxo-,ethyl ester
CAS 119694-71-2C13H14N2O7
(6-[1,3]Dioxolan-2-yl-pyridin-2-yl)dimethyl-amine chemical structure, C10H14N2O2, CAS 208110-82-1
(6-[1,3]Dioxolan-2-yl-pyridin-2-yl)dimethyl-amine
CAS 208110-82-1C10H14N2O2
[6-(1,3-Dioxolan-2-yl)pyridin-2-yl]methanol chemical structure, C9H11NO3, CAS 208111-47-1
[6-(1,3-Dioxolan-2-yl)pyridin-2-yl]methanol
CAS 208111-47-1C9H11NO3
2-[1,3]Dioxolan-2-yl-6-isopropenyl-pyridine chemical structure, C11H13NO2, CAS 208111-18-6
2-[1,3]Dioxolan-2-yl-6-isopropenyl-pyridine
CAS 208111-18-6C11H13NO2