Murcko scaffold
N-Phenylcyclopentanecarboxamide scaffold
171 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 171
- With full pages
- 43
Scaffold SMILES
O=C(Nc1ccccc1)C1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 171 chemicals
N-(3-Methoxyphenyl)cyclopentanecarboxamide
CAS 543711-85-9C13H17NO2
N-(4-Propan-2-ylphenyl)cyclopentanecarboxamide
CAS 574722-08-0C15H21NO
![Dimethyl 2-[(cyclopentylcarbonyl)amino]terephthalate chemical structure, C16H19NO5, CAS 303136-51-8](/s/VHPLHTFDZOVACL-UHFFFAOYSA-N.svg)
Dimethyl 2-[(cyclopentylcarbonyl)amino]terephthalate
CAS 303136-51-8C16H19NO5
N-(5-Chloro-2-methoxyphenyl)cyclopentanecarboxamide
CAS 549519-92-8C13H16ClNO2
N-(4-Ethylphenyl)cyclopentanecarboxamide
CAS 541517-92-4C14H19NO
N-(3,4-Dimethoxyphenyl)cyclopentanecarboxamide
CAS 791841-30-0C14H19NO3
N-(4-Bromo-3-methylphenyl)cyclopentanecarboxamide
CAS 745061-26-1C13H16BrNO
Propyl 4-(cyclopentanecarbonylamino)benzoate
CAS 541529-54-8C16H21NO3
N-(4-Butylphenyl)cyclopentanecarboxamide
CAS 543693-63-6C16H23NO
2-Cyclopentaneamido-4,5-dimethoxybenzoic acid
CAS 749920-66-9C15H19NO5
Butyl 4-(cyclopentanecarbonylamino)benzoate
CAS 540757-29-7C17H23NO3
N-(3-Fluoro-4-methylphenyl)cyclopentanecarboxamide
CAS 827013-74-1C13H16FNO
N-(3-Iodophenyl)cyclopentanecarboxamide
CAS 729564-69-6C12H14INO
2,2,3,3-Tetramethyl-N-phenylcyclopentane-1-carboxamide
CAS 681467-02-7C16H23NO
Methyl 3-((2,4-dichlorophenyl)carbamoyl)-1,2,2-trimethylcyclopentanecarboxylate
CAS 313231-91-3C17H21Cl2NO3
Cambridge id 5483946
CAS 330202-45-4C18H23NO4
![3-{[4-(Aminosulfonyl)anilino]carbonyl}-1,2,2-trimethyl-1-cyclopentanecarboxylic acid chemical structure, C16H22N2O5S, CAS 313666-50-1](/s/MZQBWXRMXATBCQ-UHFFFAOYSA-N.svg)
3-{[4-(Aminosulfonyl)anilino]carbonyl}-1,2,2-trimethyl-1-cyclopentanecarboxylic acid
CAS 313666-50-1C16H22N2O5S
3-(Hydrazinecarbonyl)-2,2,3-trimethyl-N-(p-tolyl)cyclopentanecarboxamide
CAS 392251-63-7C17H25N3O2
3-(2-Hydroxy-phenylcarbamoyl)-1,2,2-trimethyl-cyclopentanecarboxylic acid
CAS 5968-14-9C16H21NO4
3-((3-Fluorophenyl)carbamoyl)-1,2,2-trimethylcyclopentanecarboxylic acid
CAS 330202-43-2C16H20FNO3
![Benzoic acid, 2-[(3-carboxy-2,2,3-trimethylcyclopentanecarbonyl)amino]-, methyl ester chemical structure, C18H23NO5, CAS 330202-44-3](/s/TVQTWEZLNOFBGS-UHFFFAOYSA-N.svg)
Benzoic acid, 2-[(3-carboxy-2,2,3-trimethylcyclopentanecarbonyl)amino]-, methyl ester
CAS 330202-44-3C18H23NO5
![3-({[4-(Diethylamino)phenyl]amino}carbonyl)-1,2,2-trimethylcyclopentanecarboxylic acid chemical structure, C20H30N2O3, CAS 5976-56-7](/s/DUOIEPVTIVMMNP-UHFFFAOYSA-N.svg)
3-({[4-(Diethylamino)phenyl]amino}carbonyl)-1,2,2-trimethylcyclopentanecarboxylic acid
CAS 5976-56-7C20H30N2O3
1,2,2-Trimethyl-3-((4-(trifluoromethoxy)phenyl)carbamoyl)cyclopentanecarboxylic acid
CAS 499183-32-3C17H20F3NO4
N-(3-Chloro-4-methoxyphenyl)cyclopentanecarboxamide
CAS 803720-23-2C13H16ClNO2
- N-[2-Methoxy-5-(trifluoromethyl)phenyl]cyclopentanecarboxamide881598-85-2C14H16F3NO2
- 3-((2,5-Dimethylphenyl)carbamoyl)-1,2,2-trimethylcyclopentanecarboxylic acid313258-38-7C18H25NO3
- 3-[(4-Fluorophenyl)carbamoyl]-1,2,2-trimethylcyclopentane-1-carboxylic acid304666-33-9C16H20FNO3
- N-(2,6-Diethylphenyl)cyclopentanecarboxamide540793-87-1C16H23NO
- N-(2-Isopropylphenyl)cyclopentanecarboxamide573993-31-4C15H21NO
- N-(2,4-Dichlorophenyl)cyclopentanecarboxamide550313-71-8C12H13Cl2NO
- 3-((3,4-Dimethylphenyl)carbamoyl)-1,2,2-trimethylcyclopentanecarboxylic acid304668-75-5C18H25NO3
- N-(4-Butan-2-ylphenyl)cyclopentanecarboxamide544463-05-0C16H23NO
- 3-[(3-Bromophenyl)carbamoyl]-2,2,3-trimethylcyclopentane-1-carboxylic acid497060-73-8C16H20BrNO3
- N-(3-Hydroxy-4-methylphenyl)cyclopentanecarboxamide796887-76-8C13H17NO2
- N-(3-Iodo-4-methylphenyl)cyclopentanecarboxamide825662-63-3C13H16INO
- N-(2-Iodophenyl)cyclopentanecarboxamide801250-91-9C12H14INO
- N-(4-Methyl-2-nitrophenyl)cyclopentanecarboxamide545437-49-8C13H16N2O3
- N-(2,6-Dimethylphenyl)-1-(2-hydroxypropanoylamino)cyclopentane-1-carboxamide6602-98-8C17H24N2O3
- N-[4-(Prop-2-enylsulfamoyl)phenyl]cyclopentanecarboxamide898137-28-5C15H20N2O3S
- N-(2-Cyanophenyl)cyclopentanecarboxamide898153-35-0C13H14N2O
- N-(2-tert-Butylphenyl)cyclopentanecarboxamide903285-74-5C16H23NO
- N-(4-Bromophenyl)-1-cyanocyclopentane-1-carboxamide879426-51-4C13H13BrN2O
- N-(2-sec-Butylphenyl)cyclopentanecarboxamide791841-35-5C16H23NO
- N-(3-Chloro-4,5-diethoxyphenyl)cyclopentanecarboxamide90257-05-9C16H22ClNO3
- N-(3,4-Diethoxy-5-methylphenyl)cyclopentanecarboxamide90257-51-5C17H25NO3
- N-(2-Bromo-4-nitrophenyl)-1,2,2,3,3,4,4,5-octafluoro-6-trifluoromethylcyclohexanecarboxamide116777-93-6C13H4BrF11N2O3
- N-(4-Ethynylphenyl)cyclopentanecarboxamide2137712-37-7C14H15NO
- Cambridge id 5974948350687-74-0C16H20ClNO3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccco1208 chemicals
O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals