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Murcko scaffold

1-Benzyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide scaffold

946 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
946
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)c1cccn(Cc2ccccc2)c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cccn(Cc2ccccc2)c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 946 chemicals

1-Benzyl-2-oxo-N-(2,4,6-trifluorophenyl)-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H13F3N2O2, CAS 338407-03-7
1-Benzyl-2-oxo-N-(2,4,6-trifluorophenyl)-1,2-dihydro-3-pyridinecarboxamide
CAS 338407-03-7C19H13F3N2O2
1-(3,4-Dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H14Cl2N2O2, CAS 338754-33-9
1-(3,4-Dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-33-9C19H14Cl2N2O2
N-(4-Chlorophenyl)-1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H13Cl3N2O2, CAS 338754-36-2
N-(4-Chlorophenyl)-1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-36-2C19H13Cl3N2O2
1-(2,6-Dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H14Cl2N2O2, CAS 338754-54-4
1-(2,6-Dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-54-4C19H14Cl2N2O2
N-(4-Chlorophenyl)-1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H13Cl3N2O2, CAS 338754-56-6
N-(4-Chlorophenyl)-1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-56-6C19H13Cl3N2O2
1-[(2,6-Dichlorophenyl)methyl]-2-oxo-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide chemical structure, C20H13Cl2F3N2O2, CAS 338754-58-8
1-[(2,6-Dichlorophenyl)methyl]-2-oxo-N-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide
CAS 338754-58-8C20H13Cl2F3N2O2
2-Oxo-N-phenyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C20H15F3N2O2, CAS 338754-70-4
2-Oxo-N-phenyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 338754-70-4C20H15F3N2O2
N-(4-Chlorophenyl)-2-oxo-1-[3-(trifluoromethyl)benzyl]-1,2-dihydro-3-pyridinecarboxamide chemical structure, C20H14ClF3N2O2, CAS 338754-72-6
N-(4-Chlorophenyl)-2-oxo-1-[3-(trifluoromethyl)benzyl]-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-72-6C20H14ClF3N2O2
2-Oxo-N-[3-(trifluoromethyl)phenyl]-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C21H14F6N2O2, CAS 338754-74-8
2-Oxo-N-[3-(trifluoromethyl)phenyl]-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 338754-74-8C21H14F6N2O2
N-(2,4-Difluorophenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide chemical structure, C20H13F5N2O2, CAS 338754-76-0
N-(2,4-Difluorophenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide
CAS 338754-76-0C20H13F5N2O2
1-[(3-Chlorophenyl)methyl]-2-oxo-N-phenylpyridine-3-carboxamide chemical structure, C19H15ClN2O2, CAS 338754-82-8
1-[(3-Chlorophenyl)methyl]-2-oxo-N-phenylpyridine-3-carboxamide
CAS 338754-82-8C19H15ClN2O2
N-(4-Chlorophenyl)-1-[(3-chlorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C19H14Cl2N2O2, CAS 338754-84-0
N-(4-Chlorophenyl)-1-[(3-chlorophenyl)methyl]-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 338754-84-0C19H14Cl2N2O2
1-(3-Chlorobenzyl)-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydro-3-pyridinecarboxamide chemical structure, C20H14ClF3N2O2, CAS 338754-86-2
1-(3-Chlorobenzyl)-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydro-3-pyridinecarboxamide
CAS 338754-86-2C20H14ClF3N2O2
1-(3-Chlorobenzyl)-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C19H13ClF2N2O2, CAS 338754-88-4
1-(3-Chlorobenzyl)-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 338754-88-4C19H13ClF2N2O2
1-(2,6-Dichlorobenzyl)-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H12Cl2F2N2O2, CAS 338755-02-5
1-(2,6-Dichlorobenzyl)-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 338755-02-5C19H12Cl2F2N2O2
1-Benzyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide chemical structure, C19H16N2O2, CAS 338755-06-9
1-Benzyl-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide
CAS 338755-06-9C19H16N2O2
1-Benzyl-N-(4-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C19H15ClN2O2, CAS 338755-08-1
1-Benzyl-N-(4-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 338755-08-1C19H15ClN2O2
1-Benzyl-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide chemical structure, C19H14F2N2O2, CAS 338755-10-5
1-Benzyl-N-(2,4-difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
CAS 338755-10-5C19H14F2N2O2
1-Benzyl-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide chemical structure, C20H15F3N2O2, CAS 338755-12-7
1-Benzyl-2-oxo-N-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide
CAS 338755-12-7C20H15F3N2O2
1-Benzyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydro-3-pyridinecarboxamide chemical structure, C20H15F3N2O3, CAS 338755-14-9
1-Benzyl-2-oxo-N-[4-(trifluoromethoxy)phenyl]-1,2-dihydro-3-pyridinecarboxamide
CAS 338755-14-9C20H15F3N2O3
1-Benzyl-N-methyl-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide chemical structure, C20H18N2O2, CAS 338755-17-2
1-Benzyl-N-methyl-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide
CAS 338755-17-2C20H18N2O2
5-Bromo-2-oxo-N-phenyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide chemical structure, C20H14BrF3N2O2, CAS 400083-36-5
5-Bromo-2-oxo-N-phenyl-1-[[3-(trifluoromethyl)phenyl]methyl]pyridine-3-carboxamide
CAS 400083-36-5C20H14BrF3N2O2
5-Chloro-1-(3,4-dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide chemical structure, C19H13Cl3N2O2, CAS 339008-85-4
5-Chloro-1-(3,4-dichlorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-3-pyridinecarboxamide
CAS 339008-85-4C19H13Cl3N2O2
1-[(2-Chloro-6-fluorophenyl)methyl]-2-oxo-N-phenylpyridine-3-carboxamide chemical structure, C19H14ClFN2O2, CAS 478066-01-2
1-[(2-Chloro-6-fluorophenyl)methyl]-2-oxo-N-phenylpyridine-3-carboxamide
CAS 478066-01-2C19H14ClFN2O2