CompoundList
Sign in
Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 721 to 768 of 988 chemicals

tert-Butyl 4-[[[2-[ethyl(prop-2-enoyl)amino]acetyl]amino]methyl]-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C18H29N3O4, CAS 2361734-63-4
tert-Butyl 4-[[[2-[ethyl(prop-2-enoyl)amino]acetyl]amino]methyl]-3,6-dihydro-2H-pyridine-1-carboxylate
CAS 2361734-63-4C18H29N3O4
tert-Butyl 4-[2-[[2-[methyl(prop-2-enoyl)amino]acetyl]amino]ethyl]-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C18H29N3O4, CAS 2361762-91-4
tert-Butyl 4-[2-[[2-[methyl(prop-2-enoyl)amino]acetyl]amino]ethyl]-3,6-dihydro-2H-pyridine-1-carboxylate
CAS 2361762-91-4C18H29N3O4
6-(Methoxymethyl)-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C7H14ClNO, CAS 2402838-86-0
6-(Methoxymethyl)-1,2,3,6-tetrahydropyridine hydrochloride
CAS 2402838-86-0C7H14ClNO
tert-Butyl 4-(nitromethyl)-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C11H18N2O4, CAS 2484905-95-3
tert-Butyl 4-(nitromethyl)-3,6-dihydro-2H-pyridine-1-carboxylate
CAS 2484905-95-3C11H18N2O4
1-O-tert-Butyl 4-O-ethyl 5-fluoro-3,6-dihydro-2H-pyridine-1,4-dicarboxylate chemical structure, C13H20FNO4, CAS 1237526-39-4
1-O-tert-Butyl 4-O-ethyl 5-fluoro-3,6-dihydro-2H-pyridine-1,4-dicarboxylate
CAS 1237526-39-4C13H20FNO4
(1,2,5,6-Tetrahydropyridin-2-yl)methanol hydrochloride chemical structure, C6H12ClNO, CAS 2413870-20-7
(1,2,5,6-Tetrahydropyridin-2-yl)methanol hydrochloride
CAS 2413870-20-7C6H12ClNO
N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]but-2-ynamide chemical structure, C15H24N2O, CAS 2411262-72-9
N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]but-2-ynamide
CAS 2411262-72-9C15H24N2O
2,2-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C7H14ClN, CAS 2408964-93-0
2,2-Dimethyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 2408964-93-0C7H14ClN
N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]prop-2-enamide chemical structure, C14H24N2O, CAS 2411277-52-4
N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]prop-2-enamide
CAS 2411277-52-4C14H24N2O
2-Chloro-N-[1-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]propanamide chemical structure, C11H19ClN2O, CAS 2411224-27-4
2-Chloro-N-[1-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]propanamide
CAS 2411224-27-4C11H19ClN2O
(E)-4-(Dimethylamino)-N-[2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]but-2-enamide chemical structure, C14H25N3O, CAS 2411337-42-1
(E)-4-(Dimethylamino)-N-[2-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]but-2-enamide
CAS 2411337-42-1C14H25N3O
(E)-N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-4-(dimethylamino)but-2-enamide chemical structure, C17H31N3O, CAS 2411337-52-3
(E)-N-[2-(4-tert-Butyl-3,6-dihydro-2H-pyridin-1-yl)ethyl]-4-(dimethylamino)but-2-enamide
CAS 2411337-52-3C17H31N3O
5-Methyl-1-(1,2,3,6-tetrahydropyridin-1-yl)hex-4-en-1-one chemical structure, C12H19NO, CAS 2418707-98-7
5-Methyl-1-(1,2,3,6-tetrahydropyridin-1-yl)hex-4-en-1-one
CAS 2418707-98-7C12H19NO
N-[2-(1-Methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]prop-2-enamide chemical structure, C11H18N2O, CAS 2411304-55-5
N-[2-(1-Methyl-3,6-dihydro-2H-pyridin-4-yl)ethyl]prop-2-enamide
CAS 2411304-55-5C11H18N2O
4-Bromo-5-methyl-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C6H11BrClN, CAS 2416234-39-2
4-Bromo-5-methyl-1,2,3,6-tetrahydropyridine hydrochloride
CAS 2416234-39-2C6H11BrClN
4-Bromo-5-methyl-1,2,3,6-tetrahydropyridine chemical structure, C6H10BrN, CAS 2416234-38-1
4-Bromo-5-methyl-1,2,3,6-tetrahydropyridine
CAS 2416234-38-1C6H10BrN
tert-Butyl 4-bromo-5-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C11H18BrNO2, CAS 2416243-47-3
tert-Butyl 4-bromo-5-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2416243-47-3C11H18BrNO2
1-Boc-2,2,6,6-tetramethyl-1,2,3,6-tetrahydro-4-pyridine-boronic acid chemical structure, C14H26BNO4, CAS 2408429-70-7
1-Boc-2,2,6,6-tetramethyl-1,2,3,6-tetrahydro-4-pyridine-boronic acid
CAS 2408429-70-7C14H26BNO4
Dimethyl(1,2,3,6-tetrahydropyridin-4-yl)phosphine oxide chemical structure, C7H14NOP, CAS 2708259-77-0
Dimethyl(1,2,3,6-tetrahydropyridin-4-yl)phosphine oxide
CAS 2708259-77-0C7H14NOP
tert-Butyl 3-hydroxy-5-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C11H19NO3, CAS 2439084-80-5
tert-Butyl 3-hydroxy-5-methyl-1,2,3,6-tetrahydropyridine-1-carboxylate
CAS 2439084-80-5C11H19NO3
5-Methyl-1,2,3,6-tetrahydropyridin-3-ol chemical structure, C6H11NO, CAS 2137895-48-6
5-Methyl-1,2,3,6-tetrahydropyridin-3-ol
CAS 2137895-48-6C6H11NO
1-O-tert-Butyl 6-O-(trifluoromethyl) 6-methyl-2,5-dihydropyridine-1,6-dicarboxylate chemical structure, C13H18F3NO4, CAS 2567580-47-4
1-O-tert-Butyl 6-O-(trifluoromethyl) 6-methyl-2,5-dihydropyridine-1,6-dicarboxylate
CAS 2567580-47-4C13H18F3NO4
3-Bromo-1,2,3,6-tetrahydropyridine chemical structure, C5H8BrN, CAS 2757959-25-2
3-Bromo-1,2,3,6-tetrahydropyridine
CAS 2757959-25-2C5H8BrN
5-Methyl-1,2,3,6-tetrahydropyridin-3-amine chemical structure, C6H12N2, CAS 2138168-41-7
5-Methyl-1,2,3,6-tetrahydropyridin-3-amine
CAS 2138168-41-7C6H12N2