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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings: 1
Scaffold atoms: 6
Chemicals: 988
With full pages: 111

Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold Open the 1,2,3,6-Tetrahydropyridine page

Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 988 chemicals

O1-tert-butyl O6-methyl 6-(trifluoromethyl)-2,5-dihydropyridine-1,6-dicarboxylate chemical structure, C13H18F3NO4, CAS 216235-48-2

O1-tert-butyl O6-methyl 6-(trifluoromethyl)-2,5-dihydropyridine-1,6-dicarboxylate

CAS 216235-48-2C₁₃H₁₈F₃NO₄

Methyl 1-methyl-1,2,3,6-tetrahydropyridine-3-carboxylate chemical structure, C8H13NO2, CAS 86447-15-6

Methyl 1-methyl-1,2,3,6-tetrahydropyridine-3-carboxylate

CAS 86447-15-6C₈H₁₃NO₂

1(2H)-Pyridinecarboxylic acid,3,6-dihydro-4-methoxy-,ethyl ester chemical structure, C9H15NO3, CAS 203984-87-6

1(2H)-Pyridinecarboxylic acid,3,6-dihydro-4-methoxy-,ethyl ester

CAS 203984-87-6C₉H₁₅NO₃

1-Ethyl-5-methyl-3,6-dihydro-2H-pyridine-6-carbonitrile chemical structure, C9H14N2, CAS 187409-16-1

1-Ethyl-5-methyl-3,6-dihydro-2H-pyridine-6-carbonitrile

CAS 187409-16-1C₉H₁₄N₂

1-(1-Methyl-1,2,5,6-tetrahydro-3-pyridinyl)ethanone chemical structure, C8H13NO, CAS 55806-53-6

1-(1-Methyl-1,2,5,6-tetrahydro-3-pyridinyl)ethanone

CAS 55806-53-6C₈H₁₃NO

tert-Butyl 4-(trifluoromethanesulfonyloxy)-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C11H16F3NO5S, CAS 138647-49-1

tert-Butyl 4-(trifluoromethanesulfonyloxy)-1,2,3,6-tetrahydropyridine-1-carboxylate

CAS 138647-49-1C₁₁H₁₆F₃NO₅S

3,4-Dimethyl-1,2,5,6-tetrahydropyridine chemical structure, C7H13N, CAS 54152-48-6

3,4-Dimethyl-1,2,5,6-tetrahydropyridine

CAS 54152-48-6C₇H₁₃N

1,1-Dimethylethyl 4-(chloromethyl)-3,6-dihydro-1(2H)-pyridinecarboxylate chemical structure, C11H18ClNO2, CAS 159635-23-1

1,1-Dimethylethyl 4-(chloromethyl)-3,6-dihydro-1(2H)-pyridinecarboxylate

CAS 159635-23-1C₁₁H₁₈ClNO₂

1-tert-Butyl 2-methyl 2,3-dihydropyridine-1,2(6H)-dicarboxylate chemical structure, C12H19NO4, CAS 164298-41-3

1-tert-Butyl 2-methyl 2,3-dihydropyridine-1,2(6H)-dicarboxylate

CAS 164298-41-3C₁₂H₁₉NO₄

4-[Methyl(propan-2-yloxy)phosphoryl]-3,6-dihydro-2H-pyridine-1-carboxylic acid 2,2,2-trichloroethyl ester chemical structure, C12H19Cl3NO4P, CAS 215930-30-6

4-[Methyl(propan-2-yloxy)phosphoryl]-3,6-dihydro-2H-pyridine-1-carboxylic acid 2,2,2-trichloroethyl ester

CAS 215930-30-6C₁₂H₁₉Cl₃NO₄P

5-Bromo-1-methyl-1,2,3,6-tetrahydropyridine chemical structure, C6H10BrN, CAS 365261-27-4

5-Bromo-1-methyl-1,2,3,6-tetrahydropyridine

CAS 365261-27-4C₆H₁₀BrN

1-tert-Butyl 3-methyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate chemical structure, C12H19NO4, CAS 125097-83-8

1-tert-Butyl 3-methyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate

CAS 125097-83-8C₁₂H₁₉NO₄

(R)-3-Hydroxymethyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester chemical structure, C11H19NO3, CAS 346408-04-6

(R)-3-Hydroxymethyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

CAS 346408-04-6C₁₁H₁₉NO₃

1(2H)-Pyridinecarboxylic acid,5,6-dihydro-2-(2-propenyl)-,methyl ester chemical structure, C10H15NO2, CAS 597581-10-7

1(2H)-Pyridinecarboxylic acid,5,6-dihydro-2-(2-propenyl)-,methyl ester

CAS 597581-10-7C₁₀H₁₅NO₂

(2S,6S)-6-(Prop-2-en-1-yl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid chemical structure, C9H13NO2, CAS 282527-18-8

(2S,6S)-6-(Prop-2-en-1-yl)-1,2,3,6-tetrahydropyridine-2-carboxylic acid

CAS 282527-18-8C₉H₁₃NO₂

Methyl 6-methoxy-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C8H13NO3, CAS 114523-69-2

Methyl 6-methoxy-3,6-dihydro-2H-pyridine-1-carboxylate

CAS 114523-69-2C₈H₁₃NO₃

tert-Butyl (3S)-3-hydroxy-1,2,3,6-tetrahydropyridine-1-carboxylate chemical structure, C10H17NO3, CAS 780782-28-7

tert-Butyl (3S)-3-hydroxy-1,2,3,6-tetrahydropyridine-1-carboxylate

CAS 780782-28-7C₁₀H₁₇NO₃

(S)-N-Boc-1,2,3,6-tetrahydro-2-pyridinecarboxylic acid chemical structure, C11H17NO4, CAS 417726-36-4

(S)-N-Boc-1,2,3,6-tetrahydro-2-pyridinecarboxylic acid

CAS 417726-36-4C₁₁H₁₇NO₄

1-(1,1-Dimethylethyl) 3,6-dihydro-1,3(2H)-pyridinedicarboxylate chemical structure, C11H17NO4, CAS 86447-14-5

1-(1,1-Dimethylethyl) 3,6-dihydro-1,3(2H)-pyridinedicarboxylate

CAS 86447-14-5C₁₁H₁₇NO₄

1-Methyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate chemical structure, C7H10F3NO3S, CAS 180692-27-7

1-Methyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate

CAS 180692-27-7C₇H₁₀F₃NO₃S

1-tert-Butyl 3-ethyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate chemical structure, C13H21NO4, CAS 126114-09-8

1-tert-Butyl 3-ethyl 1,2,5,6-tetrahydropyridine-1,3-dicarboxylate

CAS 126114-09-8C₁₃H₂₁NO₄

Pyridine, 1,2,3,6-tetrahydro-1,4-dimethyl- chemical structure, C7H13N, CAS 695-16-9

Pyridine, 1,2,3,6-tetrahydro-1,4-dimethyl-

CAS 695-16-9C₇H₁₃N

tert-Butyl 3-methoxycarbonyloxy-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C12H19NO5, CAS 656223-58-4

tert-Butyl 3-methoxycarbonyloxy-3,6-dihydro-2H-pyridine-1-carboxylate

CAS 656223-58-4C₁₂H₁₉NO₅

tert-Butyl (2S,3R)-3-hydroxy-2-(hydroxymethyl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C11H19NO4, CAS 505085-66-5

tert-Butyl (2S,3R)-3-hydroxy-2-(hydroxymethyl)-3,6-dihydropyridine-1(2H)-carboxylate

CAS 505085-66-5C₁₁H₁₉NO₄