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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 988 chemicals

1,3-Dimethyl-1,2,5,6-tetrahydropyridine-2-carbonitrile chemical structure, C8H12N2, CAS 73657-68-8
1,3-Dimethyl-1,2,5,6-tetrahydropyridine-2-carbonitrile
CAS 73657-68-8C8H12N2
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl Chloride chemical structure, C7H10ClNO, CAS 59826-28-7
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl Chloride
CAS 59826-28-7C7H10ClNO
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl chloride hydrochloride chemical structure, C7H11Cl2NO, CAS 74024-49-0
1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarbonyl chloride hydrochloride
CAS 74024-49-0C7H11Cl2NO
Ethyl (1-methyl-1,2,3,6-tetrahydropyridin-4-yl)acetate chemical structure, C10H17NO2, CAS 37123-97-0
Ethyl (1-methyl-1,2,3,6-tetrahydropyridin-4-yl)acetate
CAS 37123-97-0C10H17NO2
2-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-amine chemical structure, C8H16N2, CAS 1463-27-0
2-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-amine
CAS 1463-27-0C8H16N2
1-Methyl-2-prop-1-ynyl-3,6-dihydro-2H-pyridine chemical structure, C9H13N, CAS 81585-26-4
1-Methyl-2-prop-1-ynyl-3,6-dihydro-2H-pyridine
CAS 81585-26-4C9H13N
2,2-Dimethyl-N-(1,2,3,6-tetrahydropyridin-1-yl)propanamide chemical structure, C10H18N2O, CAS 80431-09-0
2,2-Dimethyl-N-(1,2,3,6-tetrahydropyridin-1-yl)propanamide
CAS 80431-09-0C10H18N2O
3-Ethyl-5,6-dihydro-alpha-methyl-1(2H)-pyridineacetonitrile chemical structure, C10H16N2, CAS 85856-95-7
3-Ethyl-5,6-dihydro-alpha-methyl-1(2H)-pyridineacetonitrile
CAS 85856-95-7C10H16N2
1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid chemical structure, C11H17NO4, CAS 86447-11-2
1-Boc-1,2,5,6-tetrahydropyridine-3-carboxylic acid
CAS 86447-11-2C11H17NO4
Ethyl 3-hydroxy-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C8H13NO3, CAS 66643-49-0
Ethyl 3-hydroxy-3,6-dihydropyridine-1(2H)-carboxylate
CAS 66643-49-0C8H13NO3
N-Methanesulfonyl-1,2,3,6-tetrahydro-pyridine chemical structure, C6H11NO2S, CAS 84794-10-5
N-Methanesulfonyl-1,2,3,6-tetrahydro-pyridine
CAS 84794-10-5C6H11NO2S
Ethyl 4-hydroxy-3,6-dihydro-2H-pyridine-1-carboxylate chemical structure, C8H13NO3, CAS 756774-28-4
Ethyl 4-hydroxy-3,6-dihydro-2H-pyridine-1-carboxylate
CAS 756774-28-4C8H13NO3
1,4-Dimethyl-1,2,3,6-tetrahydropyridine-2-carbonitrile--hydrogen chloride (1/1) chemical structure, C8H13ClN2, CAS 83520-91-6
1,4-Dimethyl-1,2,3,6-tetrahydropyridine-2-carbonitrile--hydrogen chloride (1/1)
CAS 83520-91-6C8H13ClN2
tert-Butyl 3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C10H17NO2, CAS 85838-94-4
tert-Butyl 3,6-dihydropyridine-1(2H)-carboxylate
CAS 85838-94-4C10H17NO2
1,2,3,6-Tetrahydropyridine-1-carbonyl chloride chemical structure, C6H8ClNO, CAS 40240-41-3
1,2,3,6-Tetrahydropyridine-1-carbonyl chloride
CAS 40240-41-3C6H8ClNO
1-Methyl-1,2,3,6-tetrahydropyridine-4-carbonyl chloride chemical structure, C7H10ClNO, CAS 116576-81-9
1-Methyl-1,2,3,6-tetrahydropyridine-4-carbonyl chloride
CAS 116576-81-9C7H10ClNO
N-Ethyl-3,6-dihydropyridine-1(2H)-carboxamide chemical structure, C8H14N2O, CAS 87943-72-4
N-Ethyl-3,6-dihydropyridine-1(2H)-carboxamide
CAS 87943-72-4C8H14N2O
N-Propyl-3,6-dihydropyridine-1(2H)-carboxamide chemical structure, C9H16N2O, CAS 87943-73-5
N-Propyl-3,6-dihydropyridine-1(2H)-carboxamide
CAS 87943-73-5C9H16N2O
N-Butyl-3,6-dihydropyridine-1(2H)-carboxamide chemical structure, C10H18N2O, CAS 87956-19-2
N-Butyl-3,6-dihydropyridine-1(2H)-carboxamide
CAS 87956-19-2C10H18N2O
N-tert-Butyl-3,6-dihydropyridine-1(2H)-carboxamide chemical structure, C10H18N2O, CAS 87943-74-6
N-tert-Butyl-3,6-dihydropyridine-1(2H)-carboxamide
CAS 87943-74-6C10H18N2O
3-Ethynyl-1-methyl-3,6-dihydro-2H-pyridine chemical structure, C8H11N, CAS 344330-23-0
3-Ethynyl-1-methyl-3,6-dihydro-2H-pyridine
CAS 344330-23-0C8H11N
1,2,3,6-Tetrahydro-2-pyridinecarbonitrile chemical structure, C6H8N2, CAS 87780-70-9
1,2,3,6-Tetrahydro-2-pyridinecarbonitrile
CAS 87780-70-9C6H8N2
Ethyl 3-(2-oxoethyl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C10H15NO3, CAS 89055-01-6
Ethyl 3-(2-oxoethyl)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 89055-01-6C10H15NO3
[1-(Ethoxycarbonyl)-1,2,3,6-tetrahydropyridin-3-yl]acetic acid chemical structure, C10H15NO4, CAS 86827-07-8
[1-(Ethoxycarbonyl)-1,2,3,6-tetrahydropyridin-3-yl]acetic acid
CAS 86827-07-8C10H15NO4