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Murcko scaffold

1,2,3,6-Tetrahydropyridine scaffold

988 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
988
With full pages
111
Scaffold SMILES

C1=CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,3,6-Tetrahydropyridine page
Murcko scaffold C1=CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 988 chemicals

Pyridine, 3-ethenyl-1,2,5,6-tetrahydro- chemical structure, C7H11N, CAS 1314900-81-6
Pyridine, 3-ethenyl-1,2,5,6-tetrahydro-
CAS 1314900-81-6C7H11N
1(1,2,5,6-Tetrahydro-1-methyl-3-pyridinyl)ethanone hydrobromide chemical structure, C8H14BrNO, CAS 88599-20-6
1(1,2,5,6-Tetrahydro-1-methyl-3-pyridinyl)ethanone hydrobromide
CAS 88599-20-6C8H14BrNO
(1,2,3,6-Tetrahydropyridin-4-yl)methanamine chemical structure, C6H12N2, CAS 1600177-37-4
(1,2,3,6-Tetrahydropyridin-4-yl)methanamine
CAS 1600177-37-4C6H12N2
1-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-one chemical structure, C8H13NO, CAS 1603352-11-9
1-(4-Methyl-1,2,3,6-tetrahydropyridin-1-yl)ethan-1-one
CAS 1603352-11-9C8H13NO
1,6,6-Trimethyl-2,3-dihydropyridine chemical structure, C8H15N, CAS 556005-48-2
1,6,6-Trimethyl-2,3-dihydropyridine
CAS 556005-48-2C8H15N
1-(Ethylsulfonyl)-1,2,3,6-tetrahydropyridine chemical structure, C7H13NO2S, CAS 51382-59-3
1-(Ethylsulfonyl)-1,2,3,6-tetrahydropyridine
CAS 51382-59-3C7H13NO2S
4-Fluoro-1,2,3,6-tetrahydropyridine hydrochloride chemical structure, C5H9ClFN, CAS 281652-11-7
4-Fluoro-1,2,3,6-tetrahydropyridine hydrochloride
CAS 281652-11-7C5H9ClFN
1-Boc-4-fluoro-1,2,3,6-tetrahydropyridine chemical structure, C10H16FNO2, CAS 281652-40-2
1-Boc-4-fluoro-1,2,3,6-tetrahydropyridine
CAS 281652-40-2C10H16FNO2
tert-Butyl 4-((trifluoromethyl)sulfonyl)-3,6-dihydropyridine-1(2H)-carboxylate chemical structure, C11H16F3NO4S, CAS 1667762-44-8
tert-Butyl 4-((trifluoromethyl)sulfonyl)-3,6-dihydropyridine-1(2H)-carboxylate
CAS 1667762-44-8C11H16F3NO4S
1-Ethyl-3,6-dihydro-2H-pyridine-5-carboxylic acid chemical structure, C8H13NO2, CAS 155394-42-6
1-Ethyl-3,6-dihydro-2H-pyridine-5-carboxylic acid
CAS 155394-42-6C8H13NO2
1,2,3,6-Tetrahydro-4-pyridinecarboxaldehyde chemical structure, C6H9NO, CAS 1314922-04-7
1,2,3,6-Tetrahydro-4-pyridinecarboxaldehyde
CAS 1314922-04-7C6H9NO
1-(1,2,3,6-Tetrahydropyridin-4-yl)ethan-1-one chemical structure, C7H11NO, CAS 1314968-69-8
1-(1,2,3,6-Tetrahydropyridin-4-yl)ethan-1-one
CAS 1314968-69-8C7H11NO
4-tert-Butyl-1,2,3,6-tetrahydropyridine chemical structure, C9H17N, CAS 61293-33-2
4-tert-Butyl-1,2,3,6-tetrahydropyridine
CAS 61293-33-2C9H17N
Diethyl 1-acetyl-3,6-dihydropyridine-2,2(1H)-dicarboxylate chemical structure, C13H19NO5, CAS 98234-57-2
Diethyl 1-acetyl-3,6-dihydropyridine-2,2(1H)-dicarboxylate
CAS 98234-57-2C13H19NO5
(2S,6S)-6-Butyl-2-(prop-2-en-1-yl)-1,2,3,6-tetrahydropyridine chemical structure, C12H21N, CAS 175478-19-0
(2S,6S)-6-Butyl-2-(prop-2-en-1-yl)-1,2,3,6-tetrahydropyridine
CAS 175478-19-0C12H21N
(1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)boronic acid chemical structure, C10H18BNO4, CAS 844501-00-4
(1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)boronic acid
CAS 844501-00-4C10H18BNO4
1,2,3,6-Tetrahydropyridin-3-amine chemical structure, C5H10N2, CAS 2680829-16-5
1,2,3,6-Tetrahydropyridin-3-amine
CAS 2680829-16-5C5H10N2
1,2,3,6-Tetrahydropyridin-3-ol hydrochloride chemical structure, C5H10ClNO, CAS 396730-55-5
1,2,3,6-Tetrahydropyridin-3-ol hydrochloride
CAS 396730-55-5C5H10ClNO
1-t-Butoxycarbonyl-4-trimethylstannyl-1,2,5,6-tetrahydropyridine chemical structure, C13H25NO2Sn, CAS 162046-38-0
1-t-Butoxycarbonyl-4-trimethylstannyl-1,2,5,6-tetrahydropyridine
CAS 162046-38-0C13H25NO2Sn
1-(tert-Butyl) 3-ethyl 4-(((trifluoromethyl)sulfonyl)oxy)-5,6-dihydropyridine-1,3(2H)-dicarboxylate chemical structure, C14H20F3NO7S, CAS 176525-98-7
1-(tert-Butyl) 3-ethyl 4-(((trifluoromethyl)sulfonyl)oxy)-5,6-dihydropyridine-1,3(2H)-dicarboxylate
CAS 176525-98-7C14H20F3NO7S
1-tert-Butyl 4-ethyl 5-(trifluoromethanesulfonyloxy)-1,2,3,6-tetrahydropyridine-1,4-dicarboxylate chemical structure, C14H20F3NO7S, CAS 455954-80-0
1-tert-Butyl 4-ethyl 5-(trifluoromethanesulfonyloxy)-1,2,3,6-tetrahydropyridine-1,4-dicarboxylate
CAS 455954-80-0C14H20F3NO7S
(1-Boc-1,2,5,6-tetrahydropyridin-3-yl)methanol chemical structure, C11H19NO3, CAS 126114-07-6
(1-Boc-1,2,5,6-tetrahydropyridin-3-yl)methanol
CAS 126114-07-6C11H19NO3
tert-Butyl 5-formyl-3,6-dihydro-1(2H)-pyridinecarboxylate chemical structure, C11H17NO3, CAS 406212-52-0
tert-Butyl 5-formyl-3,6-dihydro-1(2H)-pyridinecarboxylate
CAS 406212-52-0C11H17NO3
Guanidine, N-(2-(3,6-dihydro-4-methyl-1(2H)-pyridinyl)ethyl)-, sulfate (1:1) chemical structure, C9H20N4O4S, CAS 1562-71-6
Guanidine, N-(2-(3,6-dihydro-4-methyl-1(2H)-pyridinyl)ethyl)-, sulfate (1:1)
CAS 1562-71-6C9H20N4O4S