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Murcko scaffold

Ring system with 2 rings and 14 atoms

135 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
135
With full pages
7
Scaffold SMILES

O=C(Nc1cn[nH]c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cn[nH]c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 135 chemicals

4-Nitro-N-(1,3,5-trimethylpyrazol-4-yl)benzamide chemical structure, C13H14N4O3, CAS 356564-74-4
4-Nitro-N-(1,3,5-trimethylpyrazol-4-yl)benzamide
CAS 356564-74-4C13H14N4O3
4-Chloro-N-(1,3,5-trimethylpyrazol-4-yl)benzamide chemical structure, C13H14ClN3O, CAS 302561-06-4
4-Chloro-N-(1,3,5-trimethylpyrazol-4-yl)benzamide
CAS 302561-06-4C13H14ClN3O
2,4-Dichloro-N-(3,5-dimethyl-1H-pyrazol-4-yl)benzamide chemical structure, C12H11Cl2N3O, CAS 377054-69-8
2,4-Dichloro-N-(3,5-dimethyl-1H-pyrazol-4-yl)benzamide
CAS 377054-69-8C12H11Cl2N3O
2-Chloro-N-(1-ethyl-3,5-dimethylpyrazol-4-yl)-4-nitrobenzamide chemical structure, C14H15ClN4O3, CAS 490013-75-7
2-Chloro-N-(1-ethyl-3,5-dimethylpyrazol-4-yl)-4-nitrobenzamide
CAS 490013-75-7C14H15ClN4O3
4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide chemical structure, C17H22N4O3, CAS 139756-03-9
4-(2-Ethoxybenzamido)-1-methyl-3-propylpyrazole-5-carboxamide
CAS 139756-03-9C17H22N4O3
3-Ethoxy-N-(1-ethyl-3,5-dimethylpyrazol-4-yl)benzamide chemical structure, C16H21N3O2, CAS 514856-26-9
3-Ethoxy-N-(1-ethyl-3,5-dimethylpyrazol-4-yl)benzamide
CAS 514856-26-9C16H21N3O2
2,6-Dichloro-N-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)benzamide chemical structure, C14H15Cl2N3O, CAS 515177-08-9
2,6-Dichloro-N-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)benzamide
CAS 515177-08-9C14H15Cl2N3O
5-Chloro-N-(1,3-dimethyl-1H-pyrazol-4-yl)-2-nitrobenzamide chemical structure, C12H11ClN4O3, CAS 515150-45-5
5-Chloro-N-(1,3-dimethyl-1H-pyrazol-4-yl)-2-nitrobenzamide
CAS 515150-45-5C12H11ClN4O3
4-{4-[(2,6-Difluorobenzoyl)amino]-1H-pyrazol-1-yl}butanoic acid chemical structure, C14H13F2N3O3, CAS 955967-02-9
4-{4-[(2,6-Difluorobenzoyl)amino]-1H-pyrazol-1-yl}butanoic acid
CAS 955967-02-9C14H13F2N3O3
Ethyl {4-[(4-chloro-3-nitrobenzoyl)amino]-3,5-dimethyl-1H-pyrazol-1-yl}acetate chemical structure, C16H17ClN4O5, CAS 955963-27-6
Ethyl {4-[(4-chloro-3-nitrobenzoyl)amino]-3,5-dimethyl-1H-pyrazol-1-yl}acetate
CAS 955963-27-6C16H17ClN4O5
Ethyl (4-{[(3-chlorophenyl)carbonyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)acetate chemical structure, C16H18ClN3O3, CAS 956360-34-2
Ethyl (4-{[(3-chlorophenyl)carbonyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)acetate
CAS 956360-34-2C16H18ClN3O3
Ethyl {3,5-dimethyl-4-[(3-methyl-4-nitrobenzoyl)amino]-1H-pyrazol-1-yl}acetate chemical structure, C17H20N4O5, CAS 955961-94-1
Ethyl {3,5-dimethyl-4-[(3-methyl-4-nitrobenzoyl)amino]-1H-pyrazol-1-yl}acetate
CAS 955961-94-1C17H20N4O5
1H-Pyrazole-1-acetic acid, 3,5-dimethyl-4-[(3,4,5-trimethoxybenzoyl)amino]-, ethyl ester chemical structure, C19H25N3O6, CAS 956358-73-9
1H-Pyrazole-1-acetic acid, 3,5-dimethyl-4-[(3,4,5-trimethoxybenzoyl)amino]-, ethyl ester
CAS 956358-73-9C19H25N3O6
[4-(3,4-Dichlorobenzoylamino)-3,5-dimethylpyrazol-1-yl]acetic acid, ethyl ester chemical structure, C16H17Cl2N3O3, CAS 956360-89-7
[4-(3,4-Dichlorobenzoylamino)-3,5-dimethylpyrazol-1-yl]acetic acid, ethyl ester
CAS 956360-89-7C16H17Cl2N3O3
Ethyl 2-{4-[(2,4-dichlorophenyl)carbonylamino]-3,5-dimethylpyrazolyl}acetate chemical structure, C16H17Cl2N3O3, CAS 955964-87-1
Ethyl 2-{4-[(2,4-dichlorophenyl)carbonylamino]-3,5-dimethylpyrazolyl}acetate
CAS 955964-87-1C16H17Cl2N3O3
Ethyl 3,5-dimethyl-4-((3-nitrobenzoyl)amino)-1H-pyrazole-1-acetate chemical structure, C16H18N4O5, CAS 955965-09-0
Ethyl 3,5-dimethyl-4-((3-nitrobenzoyl)amino)-1H-pyrazole-1-acetate
CAS 955965-09-0C16H18N4O5
Ethyl (4-{[(2-ethoxyphenyl)carbonyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)acetate chemical structure, C18H23N3O4, CAS 955965-51-2
Ethyl (4-{[(2-ethoxyphenyl)carbonyl]amino}-3,5-dimethyl-1H-pyrazol-1-yl)acetate
CAS 955965-51-2C18H23N3O4
[4-(5-Chloro-2-methoxybenzoylamino)-3,5-dimethylpyrazol-1-yl]acetic acid, ethyl ester chemical structure, C17H20ClN3O4, CAS 955962-04-6
[4-(5-Chloro-2-methoxybenzoylamino)-3,5-dimethylpyrazol-1-yl]acetic acid, ethyl ester
CAS 955962-04-6C17H20ClN3O4
Methyl 4-{N-[1-(methylethyl)pyrazol-4-yl]carbamoyl}benzoate chemical structure, C15H17N3O3, CAS 956049-45-9
Methyl 4-{N-[1-(methylethyl)pyrazol-4-yl]carbamoyl}benzoate
CAS 956049-45-9C15H17N3O3
Methyl 4-(4-chlorobenzamido)-1-ethyl-3-methyl-1H-pyrazole-5-carboxylate chemical structure, C15H16ClN3O3, CAS 4784-31-0
Methyl 4-(4-chlorobenzamido)-1-ethyl-3-methyl-1H-pyrazole-5-carboxylate
CAS 4784-31-0C15H16ClN3O3
2,4-Difluoro-N-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]benzenecarboxamide chemical structure, C12H8F5N3O, CAS 477709-59-4
2,4-Difluoro-N-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]benzenecarboxamide
CAS 477709-59-4C12H8F5N3O
2-Chloro-N-(3,5-dimethyl-1H-pyrazol-4-yl)-5-nitrobenzamide chemical structure, C12H11ClN4O3, CAS 333327-51-8
2-Chloro-N-(3,5-dimethyl-1H-pyrazol-4-yl)-5-nitrobenzamide
CAS 333327-51-8C12H11ClN4O3
N-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-3,5-dimethylbenzamide chemical structure, C16H21N3O, CAS 515176-97-3
N-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-3,5-dimethylbenzamide
CAS 515176-97-3C16H21N3O
2-Methyl-N-propyl-4-[[4-(2,2,2-trifluoroethoxymethyl)benzoyl]amino]pyrazole-3-carboxamide chemical structure, C18H21F3N4O3, CAS 1005690-93-6
2-Methyl-N-propyl-4-[[4-(2,2,2-trifluoroethoxymethyl)benzoyl]amino]pyrazole-3-carboxamide
CAS 1005690-93-6C18H21F3N4O3