CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
8
With full pages
3
Scaffold SMILES

O=C1Nc2ccccc2C1Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C1Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-(4-Methylanilino)-2-oxo-1H-indole-3-carbonitrile chemical structure, C16H13N3O, CAS 306956-50-3
3-(4-Methylanilino)-2-oxo-1H-indole-3-carbonitrile
CAS 306956-50-3C16H13N3O
3-(2,4-Dimethylanilino)-2-oxo-1H-indole-3-carbonitrile chemical structure, C17H15N3O, CAS 380644-05-3
3-(2,4-Dimethylanilino)-2-oxo-1H-indole-3-carbonitrile
CAS 380644-05-3C17H15N3O
Methyl 4-[(3-cyano-2-oxo-2,3-dihydro-1H-indol-3-yl)amino]benzoate chemical structure, C17H13N3O3, CAS 380644-08-6
Methyl 4-[(3-cyano-2-oxo-2,3-dihydro-1H-indol-3-yl)amino]benzoate
CAS 380644-08-6C17H13N3O3
3-(3,4-Dimethylanilino)-2-oxo-1H-indole-3-carbonitrile chemical structure, C17H15N3O, CAS 380644-03-1
3-(3,4-Dimethylanilino)-2-oxo-1H-indole-3-carbonitrile
CAS 380644-03-1C17H15N3O
3-(2,5-Dimethylanilino)-2-oxoindoline-3-carbonitrile chemical structure, C17H15N3O, CAS 380644-04-2
3-(2,5-Dimethylanilino)-2-oxoindoline-3-carbonitrile
CAS 380644-04-2C17H15N3O
3-Anilino-1-prop-2-yn-1-yl-1,3-dihydro-2H-indol-2-one chemical structure, C17H14N2O, CAS 1169930-57-7
3-Anilino-1-prop-2-yn-1-yl-1,3-dihydro-2H-indol-2-one
CAS 1169930-57-7C17H14N2O
3-[(4-Methoxyphenyl)amino]-1,3-dihydro-2H-indol-2-one chemical structure, C15H14N2O2, CAS 1099622-05-5
3-[(4-Methoxyphenyl)amino]-1,3-dihydro-2H-indol-2-one
CAS 1099622-05-5C15H14N2O2
2H-Indol-2-one, 1,3-dihydro-3-methyl-3-(phenylamino)-, (3R)- chemical structure, C15H14N2O, CAS 1310862-15-7
2H-Indol-2-one, 1,3-dihydro-3-methyl-3-(phenylamino)-, (3R)-
CAS 1310862-15-7C15H14N2O