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Murcko scaffold

2-(2-Thiazolyl)pyridine scaffold

159 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
159
With full pages
17
Scaffold SMILES

c1ccc(-c2nccs2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2-Thiazolyl)pyridine page
Murcko scaffold c1ccc(-c2nccs2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 159 chemicals

4-Thiazoleacetic acid, 2-(2-pyridyl)- chemical structure, C10H8N2O2S, CAS 34272-68-9
4-Thiazoleacetic acid, 2-(2-pyridyl)-
CAS 34272-68-9C10H8N2O2S
2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid chemical structure, C10H8N2O2S, CAS 34418-48-9
2-(2-Pyridyl)-4-methylthiazole-5-carboxylic acid
CAS 34418-48-9C10H8N2O2S
2-[2-(Pyridin-2-yl)-1,3-thiazol-4-yl]ethan-1-amine chemical structure, C10H11N3S, CAS 938377-79-8
2-[2-(Pyridin-2-yl)-1,3-thiazol-4-yl]ethan-1-amine
CAS 938377-79-8C10H11N3S
1-(4-Methyl-2-(pyridin-2-yl)thiazol-5-yl)ethanone chemical structure, C11H10N2OS, CAS 478257-65-7
1-(4-Methyl-2-(pyridin-2-yl)thiazol-5-yl)ethanone
CAS 478257-65-7C11H10N2OS
2-[4-(Chloromethyl)-1,3-thiazol-2-yl]pyridine chemical structure, C9H7ClN2S, CAS 342025-41-6
2-[4-(Chloromethyl)-1,3-thiazol-2-yl]pyridine
CAS 342025-41-6C9H7ClN2S
2-(Pyridin-2-yl)-1,3-thiazole-4-carbaldehyde chemical structure, C9H6N2OS, CAS 173838-60-3
2-(Pyridin-2-yl)-1,3-thiazole-4-carbaldehyde
CAS 173838-60-3C9H6N2OS
Ethyl 4-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxylate chemical structure, C13H11F3N2O2S, CAS 175277-54-0
Ethyl 4-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxylate
CAS 175277-54-0C13H11F3N2O2S
Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazole-4-carboxylate chemical structure, C12H8ClF3N2O2S, CAS 257295-33-3
Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)thiazole-4-carboxylate
CAS 257295-33-3C12H8ClF3N2O2S
Ethyl 4-methyl-2-(pyridin-2-yl)thiazole-5-carboxylate chemical structure, C12H12N2O2S, CAS 383146-88-1
Ethyl 4-methyl-2-(pyridin-2-yl)thiazole-5-carboxylate
CAS 383146-88-1C12H12N2O2S
5-Methyl-2-(2-pyridinyl)-1,3-thiazol-4-ol chemical structure, C9H8N2OS, CAS 131786-47-5
5-Methyl-2-(2-pyridinyl)-1,3-thiazol-4-ol
CAS 131786-47-5C9H8N2OS
1-(2-(Pyridin-2-yl)thiazol-5-yl)ethanone chemical structure, C10H8N2OS, CAS 383147-02-2
1-(2-(Pyridin-2-yl)thiazol-5-yl)ethanone
CAS 383147-02-2C10H8N2OS
N-Allyl-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide chemical structure, C13H13N3OS, CAS 400079-05-2
N-Allyl-4-methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
CAS 400079-05-2C13H13N3OS
N,4-dimethyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide chemical structure, C11H11N3OS, CAS 400079-06-3
N,4-dimethyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
CAS 400079-06-3C11H11N3OS
4-Methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide chemical structure, C10H9N3OS, CAS 400079-07-4
4-Methyl-2-(2-pyridinyl)-1,3-thiazole-5-carboxamide
CAS 400079-07-4C10H9N3OS
(E)-3-(Dimethylamino)-1-[2-(2-pyridinyl)-1,3-thiazol-5-yl]-2-propen-1-one chemical structure, C13H13N3OS, CAS 383147-65-7
(E)-3-(Dimethylamino)-1-[2-(2-pyridinyl)-1,3-thiazol-5-yl]-2-propen-1-one
CAS 383147-65-7C13H13N3OS
Methyl 4-methyl-2-(pyridin-2-yl)thiazole-5-carboxylate chemical structure, C11H10N2O2S, CAS 640743-55-1
Methyl 4-methyl-2-(pyridin-2-yl)thiazole-5-carboxylate
CAS 640743-55-1C11H10N2O2S
Ethyl 2-pyridin-2-yl-1,3-thiazole-4-carboxylate chemical structure, C11H10N2O2S, CAS 161772-80-1
Ethyl 2-pyridin-2-yl-1,3-thiazole-4-carboxylate
CAS 161772-80-1C11H10N2O2S
[2-(Pyridin-2-yl)-1,3-thiazol-4-yl]methanol chemical structure, C9H8N2OS, CAS 173838-59-0
[2-(Pyridin-2-yl)-1,3-thiazol-4-yl]methanol
CAS 173838-59-0C9H8N2OS
6-(Thiazol-2-yl)pyridine-2-carboxaldehyde chemical structure, C9H6N2OS, CAS 208111-06-2
6-(Thiazol-2-yl)pyridine-2-carboxaldehyde
CAS 208111-06-2C9H6N2OS
4-Thiazolecarboxylic acid,5-chloro-2-(2-pyridinyl)-,ethyl ester chemical structure, C11H9ClN2O2S, CAS 425392-50-3
4-Thiazolecarboxylic acid,5-chloro-2-(2-pyridinyl)-,ethyl ester
CAS 425392-50-3C11H9ClN2O2S
2-(Pyridin-2-yl)-1,3-thiazol-4-amine chemical structure, C8H7N3S, CAS 93209-74-6
2-(Pyridin-2-yl)-1,3-thiazol-4-amine
CAS 93209-74-6C8H7N3S
2-(2-Thiazolyl)pyridine chemical structure, C8H6N2S, CAS 2433-17-2
2-(2-Thiazolyl)pyridine
CAS 2433-17-2C8H6N2S
2-(Pyridin-2-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C9H6N2O2S, CAS 115311-41-6
2-(Pyridin-2-yl)-1,3-thiazole-4-carboxylic acid
CAS 115311-41-6C9H6N2O2S
2-(6-Methylpyridin-2-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C10H8N2O2S, CAS 115311-42-7
2-(6-Methylpyridin-2-yl)-1,3-thiazole-4-carboxylic acid
CAS 115311-42-7C10H8N2O2S