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Murcko scaffold

5-Phenylisothiazole scaffold

147 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
147
With full pages
6
Scaffold SMILES

c1ccc(-c2ccns2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenylisothiazole page
Murcko scaffold c1ccc(-c2ccns2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 147 chemicals

5-Phenylisothiazole chemical structure, C9H7NS, CAS 1075-21-4
5-Phenylisothiazole
CAS 1075-21-4C9H7NS
5-(4-Methylphenyl)-1,2-thiazole chemical structure, C10H9NS, CAS 49602-75-7
5-(4-Methylphenyl)-1,2-thiazole
CAS 49602-75-7C10H9NS
5-(4-Methoxyphenyl)isothiazole chemical structure, C10H9NOS, CAS 10514-28-0
5-(4-Methoxyphenyl)isothiazole
CAS 10514-28-0C10H9NOS
4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide chemical structure, C10H8N4O3S, CAS 72632-83-8
4-Amino-5-(4-nitrophenyl)-1,2-thiazole-3-carboxamide
CAS 72632-83-8C10H8N4O3S
3-Methoxy-5-phenylisothiazole-4-carbonitrile chemical structure, C11H8N2OS, CAS 18174-82-8
3-Methoxy-5-phenylisothiazole-4-carbonitrile
CAS 18174-82-8C11H8N2OS
4-Isothiazolecarbonitrile, 3-(methylthio)-5-phenyl- chemical structure, C11H8N2S2, CAS 221006-20-8
4-Isothiazolecarbonitrile, 3-(methylthio)-5-phenyl-
CAS 221006-20-8C11H8N2S2
3-Methyl-5-phenyl-1,2-thiazole chemical structure, C10H9NS, CAS 1732-45-2
3-Methyl-5-phenyl-1,2-thiazole
CAS 1732-45-2C10H9NS
5-[4-(Bromomethyl)phenyl]-3-chloro-4-isothiazolecarbonitrile chemical structure, C11H6BrClN2S, CAS 959063-64-0
5-[4-(Bromomethyl)phenyl]-3-chloro-4-isothiazolecarbonitrile
CAS 959063-64-0C11H6BrClN2S
3-Chloro-5-phenylisothiazole-4-carboxylic acid chemical structure, C10H6ClNO2S, CAS 86125-06-6
3-Chloro-5-phenylisothiazole-4-carboxylic acid
CAS 86125-06-6C10H6ClNO2S
4-Bromo-3-methyl-5-phenylisothiazole chemical structure, C10H8BrNS, CAS 1732-51-0
4-Bromo-3-methyl-5-phenylisothiazole
CAS 1732-51-0C10H8BrNS
3-Chloro-5-phenylisothiazole-4-carboxamide chemical structure, C10H7ClN2OS, CAS 457960-33-7
3-Chloro-5-phenylisothiazole-4-carboxamide
CAS 457960-33-7C10H7ClN2OS
3-Chloro-5-phenylisothiazole-4-carbonitrile chemical structure, C10H5ClN2S, CAS 28989-23-3
3-Chloro-5-phenylisothiazole-4-carbonitrile
CAS 28989-23-3C10H5ClN2S
3-Chloro-5-(4-methylphenyl)isothiazole-4-carbonitrile chemical structure, C11H7ClN2S, CAS 662138-23-0
3-Chloro-5-(4-methylphenyl)isothiazole-4-carbonitrile
CAS 662138-23-0C11H7ClN2S
Methyl 2-{[4-(3-chloro-4-cyanoisothiazol-5-yl)benzyl]thio}acetate chemical structure, C14H11ClN2O2S2, CAS 662138-31-0
Methyl 2-{[4-(3-chloro-4-cyanoisothiazol-5-yl)benzyl]thio}acetate
CAS 662138-31-0C14H11ClN2O2S2
3-Chloro-5-(2-chlorophenyl)-1,2-thiazole-4-carbonitrile chemical structure, C10H4Cl2N2S, CAS 28989-25-5
3-Chloro-5-(2-chlorophenyl)-1,2-thiazole-4-carbonitrile
CAS 28989-25-5C10H4Cl2N2S
3-Chloro-5-(2-chlorophenyl)isothiazole-4-carboxamide chemical structure, C10H6Cl2N2OS, CAS 680212-80-0
3-Chloro-5-(2-chlorophenyl)isothiazole-4-carboxamide
CAS 680212-80-0C10H6Cl2N2OS
3-Chloro-5-(2-chlorophenyl)-1,2-thiazole-4-carboxylic acid chemical structure, C10H5Cl2NO2S, CAS 306935-52-4
3-Chloro-5-(2-chlorophenyl)-1,2-thiazole-4-carboxylic acid
CAS 306935-52-4C10H5Cl2NO2S
3-Chloro-5-[4-(trifluoromethyl)phenyl]isothiazole-4-carbonitrile chemical structure, C11H4ClF3N2S, CAS 256353-48-7
3-Chloro-5-[4-(trifluoromethyl)phenyl]isothiazole-4-carbonitrile
CAS 256353-48-7C11H4ClF3N2S
3-Chloro-5-(3-fluorophenyl)isothiazole-4-carbonitrile chemical structure, C10H4ClFN2S, CAS 256348-09-1
3-Chloro-5-(3-fluorophenyl)isothiazole-4-carbonitrile
CAS 256348-09-1C10H4ClFN2S
5-(4-Chlorophenyl)-1,2-thiazole chemical structure, C9H6ClNS, CAS 49602-89-3
5-(4-Chlorophenyl)-1,2-thiazole
CAS 49602-89-3C9H6ClNS
5-(4-Bromophenyl)isothiazole chemical structure, C9H6BrNS, CAS 49602-97-3
5-(4-Bromophenyl)isothiazole
CAS 49602-97-3C9H6BrNS
4-Bromo-5-phenylisothiazole chemical structure, C9H6BrNS, CAS 284680-72-4
4-Bromo-5-phenylisothiazole
CAS 284680-72-4C9H6BrNS
4-Isothiazolecarbonitrile, 3-chloro-5-(4-ethenylphenyl)- chemical structure, C12H7ClN2S, CAS 647016-64-6
4-Isothiazolecarbonitrile, 3-chloro-5-(4-ethenylphenyl)-
CAS 647016-64-6C12H7ClN2S
4-Isothiazolecarbonitrile, 3-chloro-5-(2-methoxyphenyl)- chemical structure, C11H7ClN2OS, CAS 647016-59-9
4-Isothiazolecarbonitrile, 3-chloro-5-(2-methoxyphenyl)-
CAS 647016-59-9C11H7ClN2OS