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Murcko scaffold

(1H-Pyrazol-3-yl)(pyrrolidin-1-yl)methanone scaffold

75 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
75
With full pages
4
Scaffold SMILES

O=C(c1cc[nH]n1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (1H-Pyrazol-3-yl)(pyrrolidin-1-yl)methanone page
Murcko scaffold O=C(c1cc[nH]n1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 75 chemicals

(4-Chloro-1,5-dimethylpyrazol-3-yl)-pyrrolidin-1-ylmethanone chemical structure, C10H14ClN3O, CAS 515830-06-5
(4-Chloro-1,5-dimethylpyrazol-3-yl)-pyrrolidin-1-ylmethanone
CAS 515830-06-5C10H14ClN3O
(2,5-Dimethyl-4-nitropyrazol-3-yl)-pyrrolidin-1-ylmethanone chemical structure, C10H14N4O3, CAS 515832-76-5
(2,5-Dimethyl-4-nitropyrazol-3-yl)-pyrrolidin-1-ylmethanone
CAS 515832-76-5C10H14N4O3
4-Nitro-1,5-dimethyl-3-(1-pyrrolidinylcarbonyl)-1H-pyrazole chemical structure, C10H14N4O3, CAS 515832-60-7
4-Nitro-1,5-dimethyl-3-(1-pyrrolidinylcarbonyl)-1H-pyrazole
CAS 515832-60-7C10H14N4O3
1-Ethyl-4-nitro-3-(1-pyrrolidinylcarbonyl)-1H-pyrazole chemical structure, C10H14N4O3, CAS 515831-39-7
1-Ethyl-4-nitro-3-(1-pyrrolidinylcarbonyl)-1H-pyrazole
CAS 515831-39-7C10H14N4O3
(4-Bromo-2-methylpyrazol-3-yl)-pyrrolidin-1-ylmethanone chemical structure, C9H12BrN3O, CAS 512826-81-2
(4-Bromo-2-methylpyrazol-3-yl)-pyrrolidin-1-ylmethanone
CAS 512826-81-2C9H12BrN3O
(4-Bromo-1-methyl-1H-pyrazol-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C9H12BrN3O, CAS 514217-44-8
(4-Bromo-1-methyl-1H-pyrazol-3-yl)(pyrrolidin-1-yl)methanone
CAS 514217-44-8C9H12BrN3O
[4-Chloro-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-pyrrolidin-1-ylmethanone chemical structure, C10H11ClF3N3O, CAS 1005673-95-9
[4-Chloro-2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-pyrrolidin-1-ylmethanone
CAS 1005673-95-9C10H11ClF3N3O
1,3-Dimethyl-5-(pyrrolidine-1-carbonyl)-1H-pyrazole-4-sulfonamide chemical structure, C10H16N4O3S, CAS 88398-70-3
1,3-Dimethyl-5-(pyrrolidine-1-carbonyl)-1H-pyrazole-4-sulfonamide
CAS 88398-70-3C10H16N4O3S
(1H-Pyrazol-3-yl)(pyrrolidin-1-yl)methanone chemical structure, C8H11N3O, CAS 276865-59-9
(1H-Pyrazol-3-yl)(pyrrolidin-1-yl)methanone
CAS 276865-59-9C8H11N3O
[4-Bromo-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl](pyrrolidin-1-yl)methanone chemical structure, C10H11BrF3N3O, CAS 1005674-17-8
[4-Bromo-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl](pyrrolidin-1-yl)methanone
CAS 1005674-17-8C10H11BrF3N3O
1-Methyl-4-nitropyrazol-5-yl pyrrolidinyl ketone chemical structure, C9H12N4O3, CAS 1005558-16-6
1-Methyl-4-nitropyrazol-5-yl pyrrolidinyl ketone
CAS 1005558-16-6C9H12N4O3
3-[3-(Pyrrolidin-1-ylcarbonyl)-1H-pyrazol-1-yl]propanoic acid chemical structure, C11H15N3O3, CAS 1006435-21-7
3-[3-(Pyrrolidin-1-ylcarbonyl)-1H-pyrazol-1-yl]propanoic acid
CAS 1006435-21-7C11H15N3O3
1-Methyl-5-(pyrrolidin-1-ylcarbonyl)-1H-pyrazole-4-carboxylic acid chemical structure, C10H13N3O3, CAS 1006455-16-8
1-Methyl-5-(pyrrolidin-1-ylcarbonyl)-1H-pyrazole-4-carboxylic acid
CAS 1006455-16-8C10H13N3O3
1-Methyl-3-(pyrrolidine-1-carbonyl)-1H-pyrazole chemical structure, C9H13N3O, CAS 1170798-18-1
1-Methyl-3-(pyrrolidine-1-carbonyl)-1H-pyrazole
CAS 1170798-18-1C9H13N3O
4-Bromo-5-methyl-3-(pyrrolidine-1-carbonyl)-1H-pyrazole chemical structure, C9H12BrN3O, CAS 1257844-81-7
4-Bromo-5-methyl-3-(pyrrolidine-1-carbonyl)-1H-pyrazole
CAS 1257844-81-7C9H12BrN3O
3-Amino-1-methylpyrazol-5-yl pyrrolidinyl ketone chemical structure, C9H14N4O, CAS 1174852-89-1
3-Amino-1-methylpyrazol-5-yl pyrrolidinyl ketone
CAS 1174852-89-1C9H14N4O
(1,3-Dimethyl-1H-pyrazol-5-yl)(pyrrolidin-1-yl)methanone chemical structure, C10H15N3O, CAS 88398-77-0
(1,3-Dimethyl-1H-pyrazol-5-yl)(pyrrolidin-1-yl)methanone
CAS 88398-77-0C10H15N3O
Methyl 1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidine-3-carboxylate chemical structure, C13H19N3O3, CAS 2099036-73-2
Methyl 1-(3-isopropyl-1H-pyrazole-5-carbonyl)pyrrolidine-3-carboxylate
CAS 2099036-73-2C13H19N3O3
1-Methyl-5-(pyrrolidine-1-carbonyl)-1H-pyrazole chemical structure, C9H13N3O, CAS 1327192-72-2
1-Methyl-5-(pyrrolidine-1-carbonyl)-1H-pyrazole
CAS 1327192-72-2C9H13N3O
(3-Amino-1H-pyrazol-5-yl)(pyrrolidin-1-yl)methanone chemical structure, C8H12N4O, CAS 1347231-42-8
(3-Amino-1H-pyrazol-5-yl)(pyrrolidin-1-yl)methanone
CAS 1347231-42-8C8H12N4O
(3-Aminopyrrolidin-1-yl)(1-methyl-1H-pyrazol-5-yl)methanone chemical structure, C9H14N4O, CAS 1248617-73-3
(3-Aminopyrrolidin-1-yl)(1-methyl-1H-pyrazol-5-yl)methanone
CAS 1248617-73-3C9H14N4O
1-(1H-Pyrazole-3-carbonyl)pyrrolidine-3-carboxylic acid chemical structure, C9H11N3O3, CAS 1343391-89-8
1-(1H-Pyrazole-3-carbonyl)pyrrolidine-3-carboxylic acid
CAS 1343391-89-8C9H11N3O3
1-(1-Methyl-1H-pyrazole-5-carbonyl)pyrrolidine-3-carboxylic acid chemical structure, C10H13N3O3, CAS 1341566-67-3
1-(1-Methyl-1H-pyrazole-5-carbonyl)pyrrolidine-3-carboxylic acid
CAS 1341566-67-3C10H13N3O3
(3-Aminopyrrolidin-1-yl)(1H-pyrazol-3-yl)methanone chemical structure, C8H12N4O, CAS 1342360-42-2
(3-Aminopyrrolidin-1-yl)(1H-pyrazol-3-yl)methanone
CAS 1342360-42-2C8H12N4O