Murcko scaffold
3-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)propanamide scaffold
230 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 23
- Chemicals
- 230
- With full pages
- 22
Scaffold SMILES
O=C(CCS(=O)(=O)c1ccccc1)Nc1nc2ccccc2s1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 230 chemicals
3-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)propanamide
CAS 878428-52-5C16H14N2O3S2
![N-(4-Methylbenzo[d]thiazol-2-yl)-3-tosylpropanamide chemical structure, C18H18N2O3S2, CAS 434920-94-2](/s/DGSMOAMAXNREPN-UHFFFAOYSA-N.svg)
N-(4-Methylbenzo[d]thiazol-2-yl)-3-tosylpropanamide
CAS 434920-94-2C18H18N2O3S2
3-(Benzenesulfonyl)-N-(4,6-dimethyl-1,3-benzothiazol-2-yl)propanamide
CAS 851456-70-7C18H18N2O3S2
3-(Benzenesulfonyl)-N-(4,7-dimethoxy-1,3-benzothiazol-2-yl)propanamide
CAS 868677-68-3C18H18N2O5S2
3-(Benzenesulfonyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)propanamide
CAS 868675-64-3C17H16N2O4S2
3-Benzenesulfonyl-N-(6-methanesulfonyl-benzothiazol-2-yl)-propionamide
CAS 868676-31-7C17H16N2O5S3
![(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide chemical structure, C17H15FN2O3S2, CAS 1321778-55-5](/s/XDBYVEISTJXBQN-UHFFFAOYSA-N.svg)
(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide
CAS 1321778-55-5C17H15FN2O3S2
![(E)-N-(6-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide chemical structure, C18H18N2O4S2, CAS 1321720-38-0](/s/FHGXDZJLTXLJTO-UHFFFAOYSA-N.svg)
(E)-N-(6-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide
CAS 1321720-38-0C18H18N2O4S2
3-(Benzenesulfonyl)-N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)propanamide
CAS 1321829-11-1C19H20N2O4S2
![(E)-N-(4-Ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide chemical structure, C20H22N2O4S2, CAS 1322255-23-1](/s/MRRXXRRDMOCGEQ-UHFFFAOYSA-N.svg)
(E)-N-(4-Ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-3-(phenylsulfonyl)propanamide
CAS 1322255-23-1C20H22N2O4S2
![3-(Benzenesulfonyl)-N-[3-(2-methoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]propanamide chemical structure, C20H22N2O4S2, CAS 1322016-26-1](/s/IWZYGFZYKJAQDV-UHFFFAOYSA-N.svg)
3-(Benzenesulfonyl)-N-[3-(2-methoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]propanamide
CAS 1322016-26-1C20H22N2O4S2
3-(Benzenesulfonyl)-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide
CAS 868675-65-4C17H16N2O4S2
3-(Benzenesulfonyl)-N-(6-methyl-1,3-benzothiazol-2-yl)propanamide
CAS 868675-66-5C17H16N2O3S2
3-(Benzenesulfonyl)-N-(4-methyl-1,3-benzothiazol-2-yl)propanamide
CAS 868675-75-6C17H16N2O3S2
![N-(6-Acetamidobenzo[d]thiazol-2-yl)-3-(phenylsulfonyl)propanamide chemical structure, C18H17N3O4S2, CAS 868675-77-8](/s/LXDUZAICBNMLFC-UHFFFAOYSA-N.svg)
N-(6-Acetamidobenzo[d]thiazol-2-yl)-3-(phenylsulfonyl)propanamide
CAS 868675-77-8C18H17N3O4S2
3-(Benzenesulfonyl)-N-(4-ethoxy-1,3-benzothiazol-2-yl)propanamide
CAS 868675-79-0C18H18N2O4S2
3-(Benzenesulfonyl)-N-(4,5-dimethyl-1,3-benzothiazol-2-yl)propanamide
CAS 868676-73-7C18H18N2O3S2
3-(Benzenesulfonyl)-N-(4-fluoro-1,3-benzothiazol-2-yl)propanamide
CAS 892843-91-3C16H13FN2O3S2
3-(Benzenesulfonyl)-N-(4,7-dimethyl-1,3-benzothiazol-2-yl)propanamide
CAS 868677-66-1C18H18N2O3S2
3-(Benzenesulfonyl)-N-(5,7-dimethyl-1,3-benzothiazol-2-yl)propanamide
CAS 892844-81-4C18H18N2O3S2
3-(Benzenesulfonyl)-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)propanamide
CAS 868677-96-7C18H18N2O4S2
3-(Benzenesulfonyl)-N-(4-chloro-1,3-benzothiazol-2-yl)propanamide
CAS 892847-61-9C16H13ClN2O3S2
3-(Benzenesulfonyl)-N-(6-fluoro-1,3-benzothiazol-2-yl)propanamide
CAS 892849-03-5C16H13FN2O3S2
![Methyl 2-[3-(benzenesulfonyl)propanoylamino]-1,3-benzothiazole-6-carboxylate chemical structure, C18H16N2O5S2, CAS 892855-84-4](/s/IMMWRWXVPJIGCK-UHFFFAOYSA-N.svg)
Methyl 2-[3-(benzenesulfonyl)propanoylamino]-1,3-benzothiazole-6-carboxylate
CAS 892855-84-4C18H16N2O5S2
- 3-(Benzenesulfonyl)-N-(3,4,5-trimethyl-1,3-benzothiazol-2-ylidene)propanamide1322011-04-0C19H20N2O3S2
- 3-(Benzenesulfonyl)-N-(5,6-dimethoxy-1,3-benzothiazol-2-yl)propanamide895443-90-0C18H18N2O5S2
- N-(3,4-Dimethyl-1,3-benzothiazol-2-ylidene)-3-(4-fluorophenyl)sulfonylpropanamide898427-36-6C18H17FN2O3S2
- N-(6-Methoxy-1,3-benzothiazol-2-yl)-3-(4-methylphenyl)sulfonylpropanamide898414-23-8C18H18N2O4S2
- N-(4-Methoxybenzo[d]thiazol-2-yl)-3-tosylpropanamide895472-29-4C18H18N2O4S2
- N-(6-Chlorobenzo[d]thiazol-2-yl)-3-tosylpropanamide895472-44-3C17H15ClN2O3S2
- N-(6-Methylbenzo[d]thiazol-2-yl)-3-tosylpropanamide895472-52-3C18H18N2O3S2
- N-(6-Nitrobenzo[d]thiazol-2-yl)-3-tosylpropanamide898436-77-6C17H15N3O5S2
- N-(4-Chlorobenzo[d]thiazol-2-yl)-3-tosylpropanamide898436-78-7C17H15ClN2O3S2
- 3-(4-Chlorophenyl)sulfonyl-N-(4-methoxy-1,3-benzothiazol-2-yl)propanamide895454-46-3C17H15ClN2O4S2
- 3-(4-Chlorobenzenesulfonyl)-N-(6-methyl-1,3-benzothiazol-2-yl)propanamide895454-67-8C17H15ClN2O3S2
- 3-((4-Chlorophenyl)sulfonyl)-N-(5,7-dimethylbenzo[d]thiazol-2-yl)propanamide895468-92-5C18H17ClN2O3S2
- 3-((4-Fluorophenyl)sulfonyl)-N-(6-methoxybenzo[d]thiazol-2-yl)propanamide895469-36-0C17H15FN2O4S2
- 3-((4-Fluorophenyl)sulfonyl)-N-(4-methoxybenzo[d]thiazol-2-yl)propanamide895469-43-9C17H15FN2O4S2
- N-(6-Chlorobenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide898414-65-8C16H12ClFN2O3S2
- 3-((4-Fluorophenyl)sulfonyl)-N-(6-methylbenzo[d]thiazol-2-yl)propanamide895469-64-4C17H15FN2O3S2
- 3-(4-Fluorobenzenesulfonyl)-N-(6-nitro-1,3-benzothiazol-2-yl)propanamide895469-78-0C16H12FN3O5S2
- N-(4-Chlorobenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide895470-07-2C16H12ClFN2O3S2
- 3-((4-Fluorophenyl)sulfonyl)-N-(4-methylbenzo[d]thiazol-2-yl)propanamide895470-70-9C17H15FN2O3S2
- N-(4,6-Dimethylbenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide895471-18-8C18H17FN2O3S2
- N-(4,5-Dimethylbenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide895449-00-0C18H17FN2O3S2
- N-(5-Chloro-4-methylbenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide895452-70-7C17H14ClFN2O3S2
- N-(7-Chloro-4-methyl-1,3-benzothiazol-2-yl)-3-(4-fluorophenyl)sulfonylpropanamide895452-81-0C17H14ClFN2O3S2
- N-(4,7-Dimethylbenzo[d]thiazol-2-yl)-3-((4-fluorophenyl)sulfonyl)propanamide898427-42-4C18H17FN2O3S2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CCS(=O)(=O)c1ccccc1)Nc1cc2c(s1)CNCC210 chemicals![Scaffold O=C(CSc1nc2ccccc2[nH]1)NCc1ccccc1](/scaffold/DLDUWMKXHKTLEW-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2ccccc2[nH]1)NCc1ccccc19 chemicals
O=C(CN1C(=O)c2ccccc2C1=O)OCC(=O)c1ccccc17 chemicals
O=C(COc1ccccc1)NNc1nc2ccccc2s16 chemicals
O=C(CN1C(=O)c2ccccc2S1(=O)=O)NCCc1ccccc16 chemicals
O=C(CCN1C(=O)c2ccccc2S1(=O)=O)NCc1ccccc15 chemicals
O=C(CN1C(=O)C2CC=CCC2C1=O)OCC(=O)c1ccccc14 chemicals
O=C(CCCN1C(=O)c2ccccc2C1=O)Nc1ccccc14 chemicals
O=C(CCN1C(=O)c2ccccc2C1=O)NCc1ccccc14 chemicals
O=C(CN1C(=O)c2ccccc2C1=O)NCCc1ccccc13 chemicals![Scaffold c1ccc(OCCCSc2nc3ccccc3[nH]2)cc1](/scaffold/IHHALNGWQIHMDL-UHFFFAOYSA-N/structure.svg)
c1ccc(OCCCSc2nc3ccccc3[nH]2)cc13 chemicals![Scaffold O=C(CSc1nc2[nH]c(=O)[nH]c(=O)c2[nH]1)OCc1ccccc1](/scaffold/KYKRBLQRSPSLBW-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2[nH]c(=O)[nH]c(=O)c2[nH]1)OCc1ccccc13 chemicals