CompoundList
Sign in
Murcko scaffold

3-Hydroxyisoquinoline scaffold

138 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
138
With full pages
14
Scaffold SMILES

O=c1cc2ccccc2c[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Hydroxyisoquinoline page
Murcko scaffold O=c1cc2ccccc2c[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 138 chemicals

1,3-Isoquinolinediol chemical structure, C9H7NO2, CAS 86-94-2
1,3-Isoquinolinediol
CAS 86-94-2C9H7NO2
2-Amino-6,7-dimethoxy-1-methyl-isoquinolin-3-one chemical structure, C12H14N2O3, CAS 37388-26-4
2-Amino-6,7-dimethoxy-1-methyl-isoquinolin-3-one
CAS 37388-26-4C12H14N2O3
Ethyl 2-(7-methyl-3-oxo-2H-isoquinolin-6-yl)acetate chemical structure, C14H15NO3, CAS 55329-69-6
Ethyl 2-(7-methyl-3-oxo-2H-isoquinolin-6-yl)acetate
CAS 55329-69-6C14H15NO3
1-Hydroxy-4-nitroso-2H-isoquinolin-3-one chemical structure, C9H6N2O3, CAS 56055-60-8
1-Hydroxy-4-nitroso-2H-isoquinolin-3-one
CAS 56055-60-8C9H6N2O3
3(2H)-Isoquinolinone, 6,7-dimethoxy-1-methyl- chemical structure, C12H13NO3, CAS 16535-98-1
3(2H)-Isoquinolinone, 6,7-dimethoxy-1-methyl-
CAS 16535-98-1C12H13NO3
6,7-Dimethoxy-1-propyl-3(2H)-isoquinolinone chemical structure, C14H17NO3, CAS 419541-58-5
6,7-Dimethoxy-1-propyl-3(2H)-isoquinolinone
CAS 419541-58-5C14H17NO3
2-Methyl-1,3,4(2H)-isoquinolinetrione 4-oxime chemical structure, C10H8N2O3, CAS 35419-27-3
2-Methyl-1,3,4(2H)-isoquinolinetrione 4-oxime
CAS 35419-27-3C10H8N2O3
6,7-Dimethoxy-1-methyl-4-nitroisoquinolin-3-ol chemical structure, C12H12N2O5, CAS 113982-73-3
6,7-Dimethoxy-1-methyl-4-nitroisoquinolin-3-ol
CAS 113982-73-3C12H12N2O5
3-Hydroxyisoquinoline chemical structure, C9H7NO, CAS 7651-81-2
3-Hydroxyisoquinoline
CAS 7651-81-2C9H7NO
1-Ethyl-6,7-dimethoxy-2H-isoquinolin-3-one chemical structure, C13H15NO3, CAS 331959-42-3
1-Ethyl-6,7-dimethoxy-2H-isoquinolin-3-one
CAS 331959-42-3C13H15NO3
1-Methylisoquinolin-3-ol chemical structure, C10H9NO, CAS 16535-89-0
1-Methylisoquinolin-3-ol
CAS 16535-89-0C10H9NO
2-Amino-1-methyl-2,3-dihydroisoquinolin-3-one chemical structure, C10H10N2O, CAS 75122-66-6
2-Amino-1-methyl-2,3-dihydroisoquinolin-3-one
CAS 75122-66-6C10H10N2O
4-Acetyl-2-hydroxyisoquinolin-3-one chemical structure, C11H9NO3, CAS 65417-65-4
4-Acetyl-2-hydroxyisoquinolin-3-one
CAS 65417-65-4C11H9NO3
6-Methoxy-1-methylisoquinolin-3(2H)-one chemical structure, C11H11NO2, CAS 114130-62-0
6-Methoxy-1-methylisoquinolin-3(2H)-one
CAS 114130-62-0C11H11NO2
7-Ethoxy-3-hydroxy-6-methoxy-1-methylisoquinoline chemical structure, C13H15NO3, CAS 114130-63-1
7-Ethoxy-3-hydroxy-6-methoxy-1-methylisoquinoline
CAS 114130-63-1C13H15NO3
7-Ethoxy-6-methoxy-1-methyl-4-nitro-3(2H)-isoquinolinone chemical structure, C13H14N2O5, CAS 113982-79-9
7-Ethoxy-6-methoxy-1-methyl-4-nitro-3(2H)-isoquinolinone
CAS 113982-79-9C13H14N2O5
1-(Methylsulfanyl)isoquinolin-3(2H)-one chemical structure, C10H9NOS, CAS 54778-99-3
1-(Methylsulfanyl)isoquinolin-3(2H)-one
CAS 54778-99-3C10H9NOS
7-Methoxy-1-(methylsulfanyl)isoquinolin-3(2H)-one chemical structure, C11H11NO2S, CAS 54779-03-2
7-Methoxy-1-(methylsulfanyl)isoquinolin-3(2H)-one
CAS 54779-03-2C11H11NO2S
6-Methoxy-1-(methylthio)isoquinolin-3(2H)-one chemical structure, C11H11NO2S, CAS 61576-29-2
6-Methoxy-1-(methylthio)isoquinolin-3(2H)-one
CAS 61576-29-2C11H11NO2S
6,7-Dimethoxy-1-methylsulfanyl-2H-isoquinolin-3-one chemical structure, C12H13NO3S, CAS 61576-30-5
6,7-Dimethoxy-1-methylsulfanyl-2H-isoquinolin-3-one
CAS 61576-30-5C12H13NO3S
7-Methyl-1-(methylthio)isoquinolin-3(2H)-one chemical structure, C11H11NOS, CAS 61576-31-6
7-Methyl-1-(methylthio)isoquinolin-3(2H)-one
CAS 61576-31-6C11H11NOS
6-Methyl-1-(methylthio)isoquinolin-3(2H)-one chemical structure, C11H11NOS, CAS 61576-32-7
6-Methyl-1-(methylthio)isoquinolin-3(2H)-one
CAS 61576-32-7C11H11NOS
5-Methyl-1-(methylthio)isoquinolin-3(2H)-one chemical structure, C11H11NOS, CAS 61576-33-8
5-Methyl-1-(methylthio)isoquinolin-3(2H)-one
CAS 61576-33-8C11H11NOS
4-Methyl-1-(methylthio)isoquinolin-3(2H)-one chemical structure, C11H11NOS, CAS 61576-34-9
4-Methyl-1-(methylthio)isoquinolin-3(2H)-one
CAS 61576-34-9C11H11NOS