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Murcko scaffold

Ring system with 3 rings and 15 atoms

57 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
57
With full pages
9
Scaffold SMILES

c1ccc(-c2nc3cccnc3s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nc3cccnc3s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

4-(Thiazolo[5,4-b]pyridin-2-yl)aniline chemical structure, C12H9N3S, CAS 121717-35-9
4-(Thiazolo[5,4-b]pyridin-2-yl)aniline
CAS 121717-35-9C12H9N3S
2-Ethyl-N-(2-methyl-5-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide chemical structure, C19H21N3OS, CAS 863594-33-6
2-Ethyl-N-(2-methyl-5-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide
CAS 863594-33-6C19H21N3OS
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide chemical structure, C15H13N3OS, CAS 863593-87-7
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide
CAS 863593-87-7C15H13N3OS
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)propanamide chemical structure, C16H15N3OS, CAS 863593-88-8
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)propanamide
CAS 863593-88-8C16H15N3OS
2,2,2-Trifluoro-N-(2-methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide chemical structure, C15H10F3N3OS, CAS 863593-89-9
2,2,2-Trifluoro-N-(2-methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide
CAS 863593-89-9C15H10F3N3OS
2-Methyl-N-(2-methyl-5-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)propanamide chemical structure, C17H17N3OS, CAS 863593-90-2
2-Methyl-N-(2-methyl-5-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)propanamide
CAS 863593-90-2C17H17N3OS
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)pentanamide chemical structure, C18H19N3OS, CAS 863593-94-6
N-(2-Methyl-5-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)pentanamide
CAS 863593-94-6C18H19N3OS
2,2,2-Trifluoro-N-(3-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide chemical structure, C14H8F3N3OS, CAS 863589-16-6
2,2,2-Trifluoro-N-(3-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)acetamide
CAS 863589-16-6C14H8F3N3OS
2-Propyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)pentanamide chemical structure, C20H23N3OS, CAS 863588-80-1
2-Propyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)pentanamide
CAS 863588-80-1C20H23N3OS
N-(3-{[1,3]Thiazolo[5,4-B]pyridin-2-YL}phenyl)propanamide chemical structure, C15H13N3OS, CAS 863589-15-5
N-(3-{[1,3]Thiazolo[5,4-B]pyridin-2-YL}phenyl)propanamide
CAS 863589-15-5C15H13N3OS
N-(2-Methyl-3-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)-2-propylpentanamide chemical structure, C21H25N3OS, CAS 863593-58-2
N-(2-Methyl-3-{[1,3]thiazolo[5,4-B]pyridin-2-YL}phenyl)-2-propylpentanamide
CAS 863593-58-2C21H25N3OS
3-Methyl-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide chemical structure, C17H17N3OS, CAS 863592-53-4
3-Methyl-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide
CAS 863592-53-4C17H17N3OS
2-Ethyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide chemical structure, C18H19N3OS, CAS 863588-98-1
2-Ethyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide
CAS 863588-98-1C18H19N3OS
N-(2-Methyl-5-(thiazolo[5,4-b]pyridin-2-yl)phenyl)ethanesulfonamide chemical structure, C15H15N3O2S2, CAS 909862-23-3
N-(2-Methyl-5-(thiazolo[5,4-b]pyridin-2-yl)phenyl)ethanesulfonamide
CAS 909862-23-3C15H15N3O2S2
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)propionamide chemical structure, C15H13N3OS, CAS 863588-40-3
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)propionamide
CAS 863588-40-3C15H13N3OS
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)isobutyramide chemical structure, C16H15N3OS, CAS 863588-42-5
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)isobutyramide
CAS 863588-42-5C16H15N3OS
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)methanesulfonamide chemical structure, C13H11N3O2S2, CAS 863594-68-7
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)methanesulfonamide
CAS 863594-68-7C13H11N3O2S2
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)butyramide chemical structure, C16H15N3OS, CAS 863588-39-0
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)butyramide
CAS 863588-39-0C16H15N3OS
2,2,2-Trifluoro-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide chemical structure, C14H8F3N3OS, CAS 863588-41-4
2,2,2-Trifluoro-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide
CAS 863588-41-4C14H8F3N3OS
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)pentanamide chemical structure, C17H17N3OS, CAS 863588-45-8
N-(4-(Thiazolo[5,4-b]pyridin-2-yl)phenyl)pentanamide
CAS 863588-45-8C17H17N3OS
2-Methoxy-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide chemical structure, C15H13N3O2S, CAS 863588-92-5
2-Methoxy-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide
CAS 863588-92-5C15H13N3O2S
2-Ethoxy-N-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide chemical structure, C16H15N3O2S, CAS 863588-93-6
2-Ethoxy-N-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide
CAS 863588-93-6C16H15N3O2S
3-Methyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide chemical structure, C17H17N3OS, CAS 863589-01-9
3-Methyl-N-(4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)butanamide
CAS 863589-01-9C17H17N3OS
2-Methoxy-N-(2-methyl-4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide chemical structure, C16H15N3O2S, CAS 912621-73-9
2-Methoxy-N-(2-methyl-4-(thiazolo[5,4-b]pyridin-2-yl)phenyl)acetamide
CAS 912621-73-9C16H15N3O2S