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Murcko scaffold

N-(Pyridin-2-yl)thiazol-2-amine scaffold

112 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
112
With full pages
4
Scaffold SMILES

c1ccc(Nc2nccs2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(Pyridin-2-yl)thiazol-2-amine page
Murcko scaffold c1ccc(Nc2nccs2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 112 chemicals

Ethanone, 1-[4-methyl-2-(2-pyridinylamino)-5-thiazolyl]- chemical structure, C11H11N3OS, CAS 71047-52-4
Ethanone, 1-[4-methyl-2-(2-pyridinylamino)-5-thiazolyl]-
CAS 71047-52-4C11H11N3OS
N-(Pyridin-2-yl)thiazol-2-amine chemical structure, C8H7N3S, CAS 54670-80-3
N-(Pyridin-2-yl)thiazol-2-amine
CAS 54670-80-3C8H7N3S
N-[4-(tert-Butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine chemical structure, C13H13ClF3N3S, CAS 338409-42-0
N-[4-(tert-Butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine
CAS 338409-42-0C13H13ClF3N3S
Ethyl 2-[2-(pyridin-2-ylamino)-1,3-thiazol-4-yl]acetate chemical structure, C12H13N3O2S, CAS 839688-91-4
Ethyl 2-[2-(pyridin-2-ylamino)-1,3-thiazol-4-yl]acetate
CAS 839688-91-4C12H13N3O2S
Ethyl 4-methyl-2-(pyridin-2-ylamino)thiazole-5-carboxylate chemical structure, C12H13N3O2S, CAS 839691-36-0
Ethyl 4-methyl-2-(pyridin-2-ylamino)thiazole-5-carboxylate
CAS 839691-36-0C12H13N3O2S
Ethyl 2-(pyridin-2-ylamino)-1,3-thiazole-4-carboxylate chemical structure, C11H11N3O2S, CAS 232596-43-9
Ethyl 2-(pyridin-2-ylamino)-1,3-thiazole-4-carboxylate
CAS 232596-43-9C11H11N3O2S
N-(5-Methyl-1,3-thiazol-2-yl)pyridin-2-amine chemical structure, C9H9N3S, CAS 402719-18-0
N-(5-Methyl-1,3-thiazol-2-yl)pyridin-2-amine
CAS 402719-18-0C9H9N3S
5-Bromo-N-(pyridin-2-yl)thiazol-2-amine chemical structure, C8H6BrN3S, CAS 54670-78-9
5-Bromo-N-(pyridin-2-yl)thiazol-2-amine
CAS 54670-78-9C8H6BrN3S
Aminothiazole 20 chemical structure, C8H6ClN3S, CAS 329794-01-6
Aminothiazole 20
CAS 329794-01-6C8H6ClN3S
2-(Pyridin-2-ylamino)-thiazole-5-carbonitrile chemical structure, C9H6N4S, CAS 329793-30-8
2-(Pyridin-2-ylamino)-thiazole-5-carbonitrile
CAS 329793-30-8C9H6N4S
2-(4-Chloromethyl-pyridin-2-ylamino)-thiazole-5-carbonitrile chemical structure, C10H7ClN4S, CAS 329794-15-2
2-(4-Chloromethyl-pyridin-2-ylamino)-thiazole-5-carbonitrile
CAS 329794-15-2C10H7ClN4S
2-((4-(((tert-Butyldimethylsilyl)oxy)methyl)pyridin-2-yl)amino)thiazole-5-carbonitrile chemical structure, C16H22N4OSSi, CAS 329794-13-0
2-((4-(((tert-Butyldimethylsilyl)oxy)methyl)pyridin-2-yl)amino)thiazole-5-carbonitrile
CAS 329794-13-0C16H22N4OSSi
2-((4-(((tert-Butyldimethylsilyl)oxy)methyl)-3-methylpyridin-2-yl)amino)thiazole-5-carbonitrile chemical structure, C17H24N4OSSi, CAS 479612-65-2
2-((4-(((tert-Butyldimethylsilyl)oxy)methyl)-3-methylpyridin-2-yl)amino)thiazole-5-carbonitrile
CAS 479612-65-2C17H24N4OSSi
2-(4-Hydroxymethyl-pyridin-2-ylamino)-thiazole-5-carbonitrile chemical structure, C10H8N4OS, CAS 329794-14-1
2-(4-Hydroxymethyl-pyridin-2-ylamino)-thiazole-5-carbonitrile
CAS 329794-14-1C10H8N4OS
2-(4-Chloromethyl-3-methyl-pyridin-2-ylamino)thiazole-5-carbonitrile chemical structure, C11H9ClN4S, CAS 479612-71-0
2-(4-Chloromethyl-3-methyl-pyridin-2-ylamino)thiazole-5-carbonitrile
CAS 479612-71-0C11H9ClN4S
2-(4-Hydroxymethyl-3-methyl-pyridin-2-ylamino)-thiazole-5-carbonitrile chemical structure, C11H10N4OS, CAS 479612-68-5
2-(4-Hydroxymethyl-3-methyl-pyridin-2-ylamino)-thiazole-5-carbonitrile
CAS 479612-68-5C11H10N4OS
N-(5-Nitropyridin-2-yl)thiazol-2-amine chemical structure, C8H6N4O2S, CAS 69824-53-9
N-(5-Nitropyridin-2-yl)thiazol-2-amine
CAS 69824-53-9C8H6N4O2S
2-[(4-Formylpyridin-2-yl)amino]-1,3-thiazole-5-carbonitrile chemical structure, C10H6N4OS, CAS 652154-15-9
2-[(4-Formylpyridin-2-yl)amino]-1,3-thiazole-5-carbonitrile
CAS 652154-15-9C10H6N4OS
N-(5-Nitro-2-thiazolyl)-2-pyridinamine chemical structure, C8H6N4O2S, CAS 54670-79-0
N-(5-Nitro-2-thiazolyl)-2-pyridinamine
CAS 54670-79-0C8H6N4O2S
2-[(Pyridin-2-yl)amino]-1,3-thiazole-4-carboxylic acid chemical structure, C9H7N3O2S, CAS 232596-44-0
2-[(Pyridin-2-yl)amino]-1,3-thiazole-4-carboxylic acid
CAS 232596-44-0C9H7N3O2S
2-[(4-Methylpyridin-2-yl)amino]-1,3-thiazole-5-carbonitrile chemical structure, C10H8N4S, CAS 329793-31-9
2-[(4-Methylpyridin-2-yl)amino]-1,3-thiazole-5-carbonitrile
CAS 329793-31-9C10H8N4S
Ethyl 2-[(6-bromo-2-pyridinyl)amino]-5-thiazolecarboxylate chemical structure, C11H10BrN3O2S, CAS 302964-39-2
Ethyl 2-[(6-bromo-2-pyridinyl)amino]-5-thiazolecarboxylate
CAS 302964-39-2C11H10BrN3O2S
Ethyl 2-[(6-bromo-2-pyridinyl)amino]-4-methyl-5-thiazolecarboxylate chemical structure, C12H12BrN3O2S, CAS 302964-40-5
Ethyl 2-[(6-bromo-2-pyridinyl)amino]-4-methyl-5-thiazolecarboxylate
CAS 302964-40-5C12H12BrN3O2S
[2-(Pyridin-2-ylamino)thiazol-5-yl]methanol chemical structure, C9H9N3OS, CAS 639858-53-0
[2-(Pyridin-2-ylamino)thiazol-5-yl]methanol
CAS 639858-53-0C9H9N3OS