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Murcko scaffold

Ring system with 2 rings and 16 atoms

48 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
48
With full pages
15
Scaffold SMILES

O=C(Cn1cccn1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1cccn1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

N-Benzyl-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide chemical structure, C14H14F3N3O, CAS 351520-70-2
N-Benzyl-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide
CAS 351520-70-2C14H14F3N3O
N-(4-Methoxybenzyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide chemical structure, C15H16F3N3O2, CAS 342615-28-5
N-(4-Methoxybenzyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide
CAS 342615-28-5C15H16F3N3O2
N-[(4-Chlorophenyl)methyl]-2-(5-methyl-3-nitropyrazol-1-yl)acetamide chemical structure, C13H13ClN4O3, CAS 353455-21-7
N-[(4-Chlorophenyl)methyl]-2-(5-methyl-3-nitropyrazol-1-yl)acetamide
CAS 353455-21-7C13H13ClN4O3
N-(4-Chloro-benzyl)-2-(4-chloro-5-methyl-3-nitro-pyrazol-1-yl)-acetamide chemical structure, C13H12Cl2N4O3, CAS 353455-65-9
N-(4-Chloro-benzyl)-2-(4-chloro-5-methyl-3-nitro-pyrazol-1-yl)-acetamide
CAS 353455-65-9C13H12Cl2N4O3
N-Benzyl-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide chemical structure, C14H16N4O3, CAS 345977-35-7
N-Benzyl-2-(3,5-dimethyl-4-nitro-1H-pyrazol-1-yl)acetamide
CAS 345977-35-7C14H16N4O3
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[(2-fluorophenyl)methyl]acetamide chemical structure, C14H15FN4O3, CAS 515177-93-2
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[(2-fluorophenyl)methyl]acetamide
CAS 515177-93-2C14H15FN4O3
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[(2-methoxyphenyl)methyl]acetamide chemical structure, C15H18N4O4, CAS 515177-34-1
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[(2-methoxyphenyl)methyl]acetamide
CAS 515177-34-1C15H18N4O4
N-[(2-Chlorophenyl)methyl]-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C12H11ClN4O3, CAS 515829-24-0
N-[(2-Chlorophenyl)methyl]-2-(4-nitropyrazol-1-yl)acetamide
CAS 515829-24-0C12H11ClN4O3
N-[(4-Methoxyphenyl)methyl]-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C13H14N4O4, CAS 957299-10-4
N-[(4-Methoxyphenyl)methyl]-2-(4-nitropyrazol-1-yl)acetamide
CAS 957299-10-4C13H14N4O4
N-Benzyl-2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide chemical structure, C14H13BrF3N3O, CAS 299405-81-5
N-Benzyl-2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetamide
CAS 299405-81-5C14H13BrF3N3O
N-Benzyl-2-(4-bromo-5-methyl-3-nitro-1H-pyrazol-1-yl)-N-methylacetamide chemical structure, C14H15BrN4O3, CAS 299405-90-6
N-Benzyl-2-(4-bromo-5-methyl-3-nitro-1H-pyrazol-1-yl)-N-methylacetamide
CAS 299405-90-6C14H15BrN4O3
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-chlorophenyl)methyl]acetamide chemical structure, C14H12BrClF3N3O, CAS 355416-47-6
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-chlorophenyl)methyl]acetamide
CAS 355416-47-6C14H12BrClF3N3O
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C15H15BrF3N3O2, CAS 355416-51-2
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-methoxyphenyl)methyl]acetamide
CAS 355416-51-2C15H15BrF3N3O2
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-chlorophenyl)methyl]acetamide chemical structure, C14H12Cl2F3N3O, CAS 351987-29-6
2-[4-Chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-chlorophenyl)methyl]acetamide
CAS 351987-29-6C14H12Cl2F3N3O
N-Benzyl-2-(4-iodo-1H-pyrazol-1-yl)acetamide chemical structure, C12H12IN3O, CAS 956691-13-7
N-Benzyl-2-(4-iodo-1H-pyrazol-1-yl)acetamide
CAS 956691-13-7C12H12IN3O
N-[(2-Chlorophenyl)methyl]-2-(4-nitropyrazol-1-yl)propanamide chemical structure, C13H13ClN4O3, CAS 957503-89-8
N-[(2-Chlorophenyl)methyl]-2-(4-nitropyrazol-1-yl)propanamide
CAS 957503-89-8C13H13ClN4O3
2-(4-Nitropyrazol-1-yl)-N-(1-phenylethyl)acetamide chemical structure, C13H14N4O3, CAS 491831-04-0
2-(4-Nitropyrazol-1-yl)-N-(1-phenylethyl)acetamide
CAS 491831-04-0C13H14N4O3
N-Benzyl-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C12H12N4O3, CAS 956202-74-7
N-Benzyl-2-(4-nitropyrazol-1-yl)acetamide
CAS 956202-74-7C12H12N4O3
N-Benzyl-2-(5-methyl-3,4-dinitro-1H-pyrazol-1-yl)acetamide chemical structure, C13H13N5O5, CAS 353455-14-8
N-Benzyl-2-(5-methyl-3,4-dinitro-1H-pyrazol-1-yl)acetamide
CAS 353455-14-8C13H13N5O5
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[1-(4-methylphenyl)ethyl]acetamide chemical structure, C16H20N4O3, CAS 515829-99-9
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[1-(4-methylphenyl)ethyl]acetamide
CAS 515829-99-9C16H20N4O3
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]acetamide chemical structure, C15H15F3N4O3, CAS 491829-12-0
2-(3,5-Dimethyl-4-nitropyrazol-1-yl)-N-[[3-(trifluoromethyl)phenyl]methyl]acetamide
CAS 491829-12-0C15H15F3N4O3
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(3,5-dimethoxyphenyl)methyl]acetamide chemical structure, C16H17BrF3N3O3, CAS 490014-98-7
2-[4-Bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(3,5-dimethoxyphenyl)methyl]acetamide
CAS 490014-98-7C16H17BrF3N3O3
N-[1-(4-tert-Butylphenyl)ethyl]-2-(4-nitropyrazol-1-yl)acetamide chemical structure, C17H22N4O3, CAS 512816-80-7
N-[1-(4-tert-Butylphenyl)ethyl]-2-(4-nitropyrazol-1-yl)acetamide
CAS 512816-80-7C17H22N4O3
N-[1-(2,5-Dimethoxyphenyl)ethyl]-2-(4-nitropyrazol-1-yl)propanamide chemical structure, C16H20N4O5, CAS 1005576-51-1
N-[1-(2,5-Dimethoxyphenyl)ethyl]-2-(4-nitropyrazol-1-yl)propanamide
CAS 1005576-51-1C16H20N4O5