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Murcko scaffold

Ring system with 4 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
5
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc2oc(-c3ccncc3)nc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccc2oc(-c3ccncc3)nc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(2-Methylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide chemical structure, C21H17N3O3, CAS 313700-14-0
2-(2-Methylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
CAS 313700-14-0C21H17N3O3
2-(4-Methoxyphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide chemical structure, C21H17N3O4, CAS 292058-98-1
2-(4-Methoxyphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
CAS 292058-98-1C21H17N3O4
2-(4-Chlorophenoxy)-2-methyl-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]propanamide chemical structure, C22H18ClN3O3, CAS 833432-18-1
2-(4-Chlorophenoxy)-2-methyl-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]propanamide
CAS 833432-18-1C22H18ClN3O3
2-(4-Chloro-3,5-dimethylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide chemical structure, C22H18ClN3O3, CAS 313699-98-8
2-(4-Chloro-3,5-dimethylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
CAS 313699-98-8C22H18ClN3O3
2-(3-Methylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide chemical structure, C21H17N3O3, CAS 797806-93-0
2-(3-Methylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
CAS 797806-93-0C21H17N3O3
2-(2,4-Dichlorophenoxy)-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]propanamide chemical structure, C21H15Cl2N3O3, CAS 701248-69-3
2-(2,4-Dichlorophenoxy)-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]propanamide
CAS 701248-69-3C21H15Cl2N3O3
2-(4-Butan-2-ylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide chemical structure, C24H23N3O3, CAS 708219-92-5
2-(4-Butan-2-ylphenoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)acetamide
CAS 708219-92-5C24H23N3O3
2-[5-Methyl-2-(propan-2-yl)phenoxy]-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide chemical structure, C24H23N3O3, CAS 590394-01-7
2-[5-Methyl-2-(propan-2-yl)phenoxy]-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide
CAS 590394-01-7C24H23N3O3
2-(4-Bromophenoxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide chemical structure, C20H14BrN3O3, CAS 4508-17-2
2-(4-Bromophenoxy)-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]acetamide
CAS 4508-17-2C20H14BrN3O3
Impdh2-IN-2 chemical structure, C21H15Cl2N3O3, CAS 1434517-02-8
Impdh2-IN-2
CAS 1434517-02-8C21H15Cl2N3O3