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Murcko scaffold

Ring system with 4 rings and 29 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
4
With full pages
1
Scaffold SMILES

O=C1CCC(N2Cc3ccc(COC(=O)Nc4ccccc4)cc3C2=O)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(N2Cc3ccc(COC(=O)Nc4ccccc4)cc3C2=O)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

[2-(2,6-Dioxo-3-piperidyl)-3-oxoisoindolin-5-yl]methyl [2-Fluoro-4-(trifluoromethoxy)phenyl]carbamate chemical structure, C22H17F4N3O6, CAS 2803881-14-1
[2-(2,6-Dioxo-3-piperidyl)-3-oxoisoindolin-5-yl]methyl [2-Fluoro-4-(trifluoromethoxy)phenyl]carbamate
CAS 2803881-14-1C22H17F4N3O6
[2-(2,6-Dioxo-3-piperidyl)-3-oxo-isoindolin-5-yl]methyl N-[2-fluoro-4-methyl-5-(trifluoromethoxy)phenyl]carbamate chemical structure, C23H19F4N3O6, CAS 2803881-73-2
[2-(2,6-Dioxo-3-piperidyl)-3-oxo-isoindolin-5-yl]methyl N-[2-fluoro-4-methyl-5-(trifluoromethoxy)phenyl]carbamate
CAS 2803881-73-2C23H19F4N3O6
[2-(2,6-Dioxopiperidin-3-yl)-3-oxo-1H-isoindol-5-yl]methyl N-[2-fluoro-5-(trifluoromethoxy)phenyl]carbamate chemical structure, C22H17F4N3O6, CAS 2803881-11-8
[2-(2,6-Dioxopiperidin-3-yl)-3-oxo-1H-isoindol-5-yl]methyl N-[2-fluoro-5-(trifluoromethoxy)phenyl]carbamate
CAS 2803881-11-8C22H17F4N3O6
GSPT1 degrader-2 chemical structure, C22H20ClN3O5, CAS 2803879-60-7
GSPT1 degrader-2
CAS 2803879-60-7C22H20ClN3O5