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Murcko scaffold

Ring system with 4 rings and 25 atoms

60 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
60
With full pages
1
Scaffold SMILES

O=S(=O)(c1ccccc1)c1cnc2ccccc2c1N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1cnc2ccccc2c1N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 60 of 60 chemicals

3-((3,4-Dimethylphenyl)sulfonyl)-6-ethoxy-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C24H29N3O3S, CAS 887212-91-1
3-((3,4-Dimethylphenyl)sulfonyl)-6-ethoxy-4-(4-methylpiperazin-1-yl)quinoline
CAS 887212-91-1C24H29N3O3S
3-((3,4-Dimethylphenyl)sulfonyl)-6,7-dimethoxy-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C24H29N3O4S, CAS 887212-92-2
3-((3,4-Dimethylphenyl)sulfonyl)-6,7-dimethoxy-4-(4-methylpiperazin-1-yl)quinoline
CAS 887212-92-2C24H29N3O4S
6-Chloro-4-(4-ethylpiperazin-1-yl)-3-tosylquinoline chemical structure, C22H24ClN3O2S, CAS 887212-94-4
6-Chloro-4-(4-ethylpiperazin-1-yl)-3-tosylquinoline
CAS 887212-94-4C22H24ClN3O2S
3-(3,4-Dimethylbenzenesulfonyl)-6-ethoxy-4-(4-ethylpiperazin-1-yl)quinoline chemical structure, C25H31N3O3S, CAS 887212-96-6
3-(3,4-Dimethylbenzenesulfonyl)-6-ethoxy-4-(4-ethylpiperazin-1-yl)quinoline
CAS 887212-96-6C25H31N3O3S
3-(4-Chlorobenzenesulfonyl)-6-ethoxy-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C22H24ClN3O3S, CAS 887213-92-5
3-(4-Chlorobenzenesulfonyl)-6-ethoxy-4-(4-methylpiperazin-1-yl)quinoline
CAS 887213-92-5C22H24ClN3O3S
3-((4-Chlorophenyl)sulfonyl)-6-ethoxy-4-(4-ethylpiperazin-1-yl)quinoline chemical structure, C23H26ClN3O3S, CAS 887214-36-0
3-((4-Chlorophenyl)sulfonyl)-6-ethoxy-4-(4-ethylpiperazin-1-yl)quinoline
CAS 887214-36-0C23H26ClN3O3S
6,7-Dimethoxy-3-((4-methoxyphenyl)sulfonyl)-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C23H27N3O5S, CAS 887214-43-9
6,7-Dimethoxy-3-((4-methoxyphenyl)sulfonyl)-4-(4-methylpiperazin-1-yl)quinoline
CAS 887214-43-9C23H27N3O5S
3-(Benzenesulfonyl)-6,7-dimethoxy-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C22H25N3O4S, CAS 872200-26-5
3-(Benzenesulfonyl)-6,7-dimethoxy-4-(4-methylpiperazin-1-yl)quinoline
CAS 872200-26-5C22H25N3O4S
6-Methoxy-3-((4-methoxyphenyl)sulfonyl)-4-(4-methylpiperazin-1-yl)quinoline chemical structure, C22H25N3O4S, CAS 950337-16-3
6-Methoxy-3-((4-methoxyphenyl)sulfonyl)-4-(4-methylpiperazin-1-yl)quinoline
CAS 950337-16-3C22H25N3O4S
3-(Benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-6,7-dimethoxyquinoline chemical structure, C23H27N3O4S, CAS 872200-27-6
3-(Benzenesulfonyl)-4-(4-ethylpiperazin-1-yl)-6,7-dimethoxyquinoline
CAS 872200-27-6C23H27N3O4S
4-(4-Ethylpiperazin-1-yl)-6-methoxy-3-(4-methoxybenzenesulfonyl)quinoline chemical structure, C23H27N3O4S, CAS 866897-32-7
4-(4-Ethylpiperazin-1-yl)-6-methoxy-3-(4-methoxybenzenesulfonyl)quinoline
CAS 866897-32-7C23H27N3O4S
3-({7-Fluoro-4-[4-(methylsulfonyl)piperazin-1-yl]quinolin-3-yl}sulfonyl)benzonitrile chemical structure, C21H19FN4O4S2, CAS 1351792-50-1
3-({7-Fluoro-4-[4-(methylsulfonyl)piperazin-1-yl]quinolin-3-yl}sulfonyl)benzonitrile
CAS 1351792-50-1C21H19FN4O4S2