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Murcko scaffold

Ring system with 4 rings and 24 atoms

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
22
With full pages
3
Scaffold SMILES

O=C(c1ccccc1)c1cnc2ccccc2c1N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cnc2ccccc2c1N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

Ethyl 1-(3-benzoyl-6-ethylquinolin-4-yl)piperidine-4-carboxylate chemical structure, C26H28N2O3, CAS 866845-01-4
Ethyl 1-(3-benzoyl-6-ethylquinolin-4-yl)piperidine-4-carboxylate
CAS 866845-01-4C26H28N2O3
Ethyl 1-[6-ethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxylate chemical structure, C27H30N2O4, CAS 866845-04-7
Ethyl 1-[6-ethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxylate
CAS 866845-04-7C27H30N2O4
Ethyl 1-(3-benzoylquinolin-4-yl)piperidine-3-carboxylate chemical structure, C24H24N2O3, CAS 866810-69-7
Ethyl 1-(3-benzoylquinolin-4-yl)piperidine-3-carboxylate
CAS 866810-69-7C24H24N2O3
Ethyl 1-[3-(4-ethoxybenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxylate chemical structure, C27H30N2O5, CAS 872206-71-8
Ethyl 1-[3-(4-ethoxybenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxylate
CAS 872206-71-8C27H30N2O5
Ethyl 1-(3-benzoyl-6-methoxyquinolin-4-yl)piperidine-3-carboxylate chemical structure, C25H26N2O4, CAS 872200-14-1
Ethyl 1-(3-benzoyl-6-methoxyquinolin-4-yl)piperidine-3-carboxylate
CAS 872200-14-1C25H26N2O4
3-Benzoyl-6-ethoxy-4-(piperidin-1-yl)quinoline chemical structure, C23H24N2O2, CAS 902942-60-3
3-Benzoyl-6-ethoxy-4-(piperidin-1-yl)quinoline
CAS 902942-60-3C23H24N2O2
1-(3-Benzoyl-6,7-dimethoxyquinolin-4-yl)piperidine-4-carboxamide chemical structure, C24H25N3O4, CAS 902942-70-5
1-(3-Benzoyl-6,7-dimethoxyquinolin-4-yl)piperidine-4-carboxamide
CAS 902942-70-5C24H25N3O4
1-(3-Benzoyl-6-ethoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride chemical structure, C24H26ClN3O3, CAS 2097888-61-2
1-(3-Benzoyl-6-ethoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride
CAS 2097888-61-2C24H26ClN3O3
Ethyl 1-(3-benzoyl-6-methoxyquinolin-4-yl)piperidine-4-carboxylate hydrochloride chemical structure, C25H27ClN2O4, CAS 2097922-13-7
Ethyl 1-(3-benzoyl-6-methoxyquinolin-4-yl)piperidine-4-carboxylate hydrochloride
CAS 2097922-13-7C25H27ClN2O4
Ethyl 1-[6-ethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxylate hydrochloride chemical structure, C27H31ClN2O4, CAS 2097867-05-3
Ethyl 1-[6-ethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxylate hydrochloride
CAS 2097867-05-3C27H31ClN2O4
1-[6,7-Dimethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxamide hydrochloride chemical structure, C25H28ClN3O4, CAS 2097861-25-9
1-[6,7-Dimethoxy-3-(4-methylbenzoyl)quinolin-4-yl]piperidine-4-carboxamide hydrochloride
CAS 2097861-25-9C25H28ClN3O4
1-[3-(4-Ethylbenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxamide hydrochloride chemical structure, C25H28ClN3O3, CAS 2097856-97-6
1-[3-(4-Ethylbenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxamide hydrochloride
CAS 2097856-97-6C25H28ClN3O3
6-Fluoro-3-(4-methoxybenzoyl)-4-(piperidin-1-yl)quinoline hydrochloride chemical structure, C22H22ClFN2O2, CAS 2097928-32-8
6-Fluoro-3-(4-methoxybenzoyl)-4-(piperidin-1-yl)quinoline hydrochloride
CAS 2097928-32-8C22H22ClFN2O2
Ethyl 1-[3-(4-ethoxybenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxylate hydrochloride chemical structure, C27H31ClN2O5, CAS 2097922-20-6
Ethyl 1-[3-(4-ethoxybenzoyl)-6-methoxyquinolin-4-yl]piperidine-4-carboxylate hydrochloride
CAS 2097922-20-6C27H31ClN2O5
1-[3-(4-Ethoxybenzoyl)-6-fluoroquinolin-4-yl]piperidine-4-carboxamide hydrochloride chemical structure, C24H25ClFN3O3, CAS 2097930-92-0
1-[3-(4-Ethoxybenzoyl)-6-fluoroquinolin-4-yl]piperidine-4-carboxamide hydrochloride
CAS 2097930-92-0C24H25ClFN3O3
1-(3-Benzoyl-6,7-dimethoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride chemical structure, C24H26ClN3O4, CAS 2097919-29-2
1-(3-Benzoyl-6,7-dimethoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride
CAS 2097919-29-2C24H26ClN3O4
3-Benzoyl-6-methoxy-4-(piperidin-1-yl)quinoline hydrochloride chemical structure, C22H23ClN2O2, CAS 2097902-46-8
3-Benzoyl-6-methoxy-4-(piperidin-1-yl)quinoline hydrochloride
CAS 2097902-46-8C22H23ClN2O2
1-(3-Benzoyl-6-methoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride chemical structure, C23H24ClN3O3, CAS 1216435-48-1
1-(3-Benzoyl-6-methoxyquinolin-4-yl)piperidine-4-carboxamide hydrochloride
CAS 1216435-48-1C23H24ClN3O3
Ethyl 1-(3-benzoyl-6-chloroquinolin-4-yl)piperidine-4-carboxylate hydrochloride chemical structure, C24H24Cl2N2O3, CAS 2097892-96-9
Ethyl 1-(3-benzoyl-6-chloroquinolin-4-yl)piperidine-4-carboxylate hydrochloride
CAS 2097892-96-9C24H24Cl2N2O3
Ethyl 1-[6-methoxy-3-(4-methoxybenzoyl)quinolin-4-yl]piperidine-4-carboxylate hydrochloride chemical structure, C26H29ClN2O5, CAS 2097922-16-0
Ethyl 1-[6-methoxy-3-(4-methoxybenzoyl)quinolin-4-yl]piperidine-4-carboxylate hydrochloride
CAS 2097922-16-0C26H29ClN2O5
6-Ethoxy-3-(4-methoxybenzoyl)-4-(piperidin-1-yl)quinoline hydrochloride chemical structure, C24H27ClN2O3, CAS 2097903-16-5
6-Ethoxy-3-(4-methoxybenzoyl)-4-(piperidin-1-yl)quinoline hydrochloride
CAS 2097903-16-5C24H27ClN2O3
1-[6-Fluoro-3-(4-methoxybenzoyl)quinolin-4-yl]piperidine-4-carboxamide hydrochloride chemical structure, C23H23ClFN3O3, CAS 2097899-43-7
1-[6-Fluoro-3-(4-methoxybenzoyl)quinolin-4-yl]piperidine-4-carboxamide hydrochloride
CAS 2097899-43-7C23H23ClFN3O3