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Murcko scaffold

2-(Benzenesulfonyl)-N-(1,3-thiazol-2-yl)acetamide scaffold

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
18
With full pages
6
Scaffold SMILES

O=C(CS(=O)(=O)c1ccccc1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Benzenesulfonyl)-N-(1,3-thiazol-2-yl)acetamide page
Murcko scaffold O=C(CS(=O)(=O)c1ccccc1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

N-(4-Methyl-1,3-thiazol-2-yl)-2-(phenylsulfonyl)acetamide chemical structure, C12H12N2O3S2, CAS 824978-52-1
N-(4-Methyl-1,3-thiazol-2-yl)-2-(phenylsulfonyl)acetamide
CAS 824978-52-1C12H12N2O3S2
2-(Benzenesulfonyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H10N2O3S2, CAS 827622-00-4
2-(Benzenesulfonyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 827622-00-4C11H10N2O3S2
N-(Thiazol-2-yl)-2-tosylacetamide chemical structure, C12H12N2O3S2, CAS 881796-29-8
N-(Thiazol-2-yl)-2-tosylacetamide
CAS 881796-29-8C12H12N2O3S2
2-(Benzenesulfonyl)-N-(4-tert-butyl-1,3-thiazol-2-yl)acetamide chemical structure, C15H18N2O3S2, CAS 794551-21-6
2-(Benzenesulfonyl)-N-(4-tert-butyl-1,3-thiazol-2-yl)acetamide
CAS 794551-21-6C15H18N2O3S2
N-(4-(tert-Butyl)thiazol-2-yl)-2-tosylacetamide chemical structure, C16H20N2O3S2, CAS 825610-56-8
N-(4-(tert-Butyl)thiazol-2-yl)-2-tosylacetamide
CAS 825610-56-8C16H20N2O3S2
N-(5-Acetyl-4-methylthiazol-2-yl)-2-tosylacetamide chemical structure, C15H16N2O4S2, CAS 895445-92-8
N-(5-Acetyl-4-methylthiazol-2-yl)-2-tosylacetamide
CAS 895445-92-8C15H16N2O4S2
N-(4-(tert-Butyl)thiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)acetamide chemical structure, C15H17ClN2O3S2, CAS 895460-64-7
N-(4-(tert-Butyl)thiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)acetamide
CAS 895460-64-7C15H17ClN2O3S2
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)acetamide chemical structure, C14H13ClN2O4S2, CAS 895461-34-4
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-chlorophenyl)sulfonyl)acetamide
CAS 895461-34-4C14H13ClN2O4S2
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-(benzenesulfonyl)acetamide chemical structure, C14H14N2O4S2, CAS 895457-22-4
N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-(benzenesulfonyl)acetamide
CAS 895457-22-4C14H14N2O4S2
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide chemical structure, C14H13FN2O4S2, CAS 895472-37-4
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-fluorophenyl)sulfonyl)acetamide
CAS 895472-37-4C14H13FN2O4S2
2-((4-Fluorophenyl)sulfonyl)-N-(thiazol-2-yl)acetamide chemical structure, C11H9FN2O3S2, CAS 895478-89-4
2-((4-Fluorophenyl)sulfonyl)-N-(thiazol-2-yl)acetamide
CAS 895478-89-4C11H9FN2O3S2
Ethyl 2-({[(4-chlorophenyl)sulfonyl]acetyl}amino)-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C15H15ClN2O5S2, CAS 895461-13-9
Ethyl 2-({[(4-chlorophenyl)sulfonyl]acetyl}amino)-4-methyl-1,3-thiazole-5-carboxylate
CAS 895461-13-9C15H15ClN2O5S2
Ethyl 2-(2-((4-fluorophenyl)sulfonyl)acetamido)thiazole-4-carboxylate chemical structure, C14H13FN2O5S2, CAS 895472-45-4
Ethyl 2-(2-((4-fluorophenyl)sulfonyl)acetamido)thiazole-4-carboxylate
CAS 895472-45-4C14H13FN2O5S2
Ethyl 2-[2-(4-fluorophenyl)sulfonylacetyl]imino-3,4-dimethyl-1,3-thiazole-5-carboxylate chemical structure, C16H17FN2O5S2, CAS 895474-77-8
Ethyl 2-[2-(4-fluorophenyl)sulfonylacetyl]imino-3,4-dimethyl-1,3-thiazole-5-carboxylate
CAS 895474-77-8C16H17FN2O5S2
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide chemical structure, C15H16N2O5S2, CAS 941951-73-1
N-(5-Acetyl-4-methylthiazol-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide
CAS 941951-73-1C15H16N2O5S2
2-((4-Methoxyphenyl)sulfonyl)-N-(thiazol-2-yl)acetamide chemical structure, C12H12N2O4S2, CAS 941988-65-4
2-((4-Methoxyphenyl)sulfonyl)-N-(thiazol-2-yl)acetamide
CAS 941988-65-4C12H12N2O4S2
2-[(4-Chlorophenyl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H11ClN2O3S2, CAS 1049106-56-0
2-[(4-Chlorophenyl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 1049106-56-0C12H11ClN2O3S2
N-(4,5-Dimethylthiazol-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide chemical structure, C14H16N2O4S2, CAS 923404-12-0
N-(4,5-Dimethylthiazol-2-yl)-2-((4-methoxyphenyl)sulfonyl)acetamide
CAS 923404-12-0C14H16N2O4S2